Best TWAS P=1.49e-07 · Best GWAS P=4.56e-07 conditioned to 0.0559
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | OR7E14P | 0.11 | 0.05 | lasso | 6 | 0.08 | 4.3e-07 | 4.6 | -5.2 | 2.0e-07 | -0.46 | 0.02 | 0.97 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NUCB2 | 0.17 | 0.06 | blup | 66 | 0.06 | 2.8e-07 | 3.8 | 5.3 | 1.5e-07 | 0.70 | 0.26 | 0.63 | TRUE |