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chr11:46,911,704-48,559,571

Best TWAS P=5.74e-09 · Best GWAS P=6.48e-08 conditioned to 0.765

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM180B	0.07	0.08	lasso	3	0.08	9.1e-10	-4.9	-5.1	3.0e-07	0.90	0.04	0.96	FALSE
2	GTEx	Brain Cortex	MTCH2	0.21	0.19	lasso	6	0.16	4.0e-05	-5.4	-5.6	2.6e-08	0.97	0.02	0.96	FALSE
3	GTEx	Colon Transverse	C1QTNF4	0.07	0.02	lasso	6	0.03	2.0e-02	-4.7	5.2	2.2e-07	-0.93	0.03	0.90	FALSE
4	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	-4.9	5.4	7.9e-08	-0.83	0.03	0.94	FALSE
5	GTEx	Lung	C1QTNF4	0.18	0.15	lasso	6	0.13	3.2e-10	-4.8	5.2	2.2e-07	-0.92	0.03	0.97	FALSE
6	GTEx	Muscle Skeletal	MTCH2	0.05	0.03	enet	15	0.04	1.5e-04	-5.3	-5.7	1.3e-08	0.92	0.02	0.98	FALSE
7	GTEx	Muscle Skeletal	C1QTNF4	0.09	0.14	lasso	3	0.13	9.9e-13	-4.9	5.2	2.5e-07	-0.92	0.08	0.92	FALSE
8	GTEx	Nerve Tibial	C1QTNF4	0.20	0.23	enet	12	0.23	1.7e-16	-4.9	5.3	1.4e-07	-0.88	0.17	0.82	FALSE
9	GTEx	Whole Blood	C1QTNF4	0.09	0.05	lasso	3	0.03	1.4e-03	-5.4	5.4	7.4e-08	-0.99	0.02	0.97	FALSE
10	METSIM	Adipose	C1QTNF4	0.24	0.31	lasso	7	0.31	1.2e-46	-5.3	5.4	6.8e-08	-0.96	0.02	0.98	FALSE
11	NTR	Blood	MTCH2	0.02	0.04	lasso	1	0.04	1.3e-11	-5.3	5.3	9.1e-08	-0.96	0.02	0.98	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	MTCH2	0.35	0.40	enet	9	0.40	4.7e-56	-5.3	-5.3	1.0e-07	0.96	0.02	0.98	FALSE
13	YFS	Blood	NUP160	0.02	0.01	blup	290	0.01	1.7e-04	-5.2	-5.4	7.1e-08	0.80	0.02	0.96	FALSE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1QTNF4	0.06	0.07	lasso	2	0.06	4.9e-06	-5.3	5.3	1.2e-07	-0.96	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	NUP160	0.03	0.01	blup	44	0.01	1.9e-03	-5.3	-5.6	2.1e-08	0.85	0.01	0.65	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C1QTNF4	0.06	0.08	lasso	3	0.08	7.5e-09	-5.3	5.3	9.2e-08	-0.97	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NUP160	0.08	0.03	blup	42	0.04	6.7e-05	-5.4	-5.8	5.7e-09	0.91	0.01	0.97	TRUE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1QTNF4	0.12	0.14	enet	4	0.16	6.5e-18	-5.3	5.3	1.1e-07	-0.95	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1QTNF4	0.13	0.16	lasso	1	0.16	3.1e-09	-5.3	5.3	1.0e-07	-0.96	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTCH2	0.11	0.11	lasso	2	0.10	6.4e-12	-5.3	-5.3	9.7e-08	0.97	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1QTNF4	0.19	0.19	lasso	3	0.19	3.2e-09	-5.3	5.3	9.7e-08	-0.97	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PSMC3	0.09	0.07	blup	39	0.06	8.7e-04	-4.9	-5.2	1.6e-07	0.85	0.01	0.98	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	C1QTNF4	0.03	0.02	blup	15	0.02	1.3e-03	-4.9	5.2	2.3e-07	-0.89	0.00	0.96	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	MYBPC3	0.04	0.02	enet	10	0.04	2.9e-05	-4.8	5.3	1.0e-07	-0.69	0.01	0.97	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUP160	0.03	0.02	enet	7	0.02	6.3e-03	-5.3	-5.3	1.1e-07	0.95	0.01	0.90	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	C1QTNF4	0.06	0.04	lasso	4	0.03	4.3e-03	-5.3	5.3	1.0e-07	-0.96	0.00	0.93	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	C1QTNF4	0.04	0.01	blup	15	0.03	7.9e-04	-4.9	5.4	5.2e-08	-0.79	0.01	0.85	FALSE