Best TWAS P=4.03e-10 · Best GWAS P=5.68e-09 conditioned to 0.8
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RBL2 | 0.22 | 0.24 | enet | 15 | 0.26 | 1.8e-31 | 4.3 | -5.2 | 1.8e-07 | -0.87 | 0.73 | 0.26 | FALSE |
| 2 | GTEx | Artery Tibial | RBL2 | 0.16 | 0.17 | enet | 11 | 0.20 | 2.1e-15 | 4.4 | -5.2 | 1.8e-07 | -0.84 | 0.53 | 0.47 | FALSE |
| 3 | GTEx | Brain Cortex | RBL2 | 0.51 | 0.45 | enet | 12 | 0.46 | 3.5e-14 | 4.1 | -5.4 | 7.6e-08 | -0.80 | 0.18 | 0.81 | FALSE |
| 4 | GTEx | Muscle Skeletal | RBL2 | 0.11 | 0.00 | lasso | 5 | 0.00 | 2.9e-01 | 5.8 | -5.3 | 1.4e-07 | -0.87 | 0.01 | 0.98 | FALSE |
| 5 | YFS | Blood | AKTIP | 0.19 | 0.27 | lasso | 13 | 0.30 | 3.3e-99 | 5.8 | 5.9 | 4.6e-09 | 0.94 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Esophageal Carcinoma | RBL2 | 0.08 | 0.04 | lasso | 3 | 0.03 | 4.4e-02 | 5.8 | 5.2 | 2.4e-07 | 0.86 | 0.01 | 0.78 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | RBL2 | 0.11 | 0.08 | blup | 44 | 0.06 | 1.5e-03 | 5.8 | -6.2 | 4.0e-10 | -0.92 | 0.00 | 0.85 | TRUE |