Best TWAS P=3.54e-08 · Best GWAS P=1.13e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MGAT3 | 0.08 | 0.04 | lasso | 4 | 0.04 | 4.3e-04 | -5.4 | 5.5 | 3.5e-08 | -0.96 | 0.03 | 0.96 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | MGAT3 | 0.15 | 0.01 | lasso | 4 | 0.00 | 2.3e-01 | -5.3 | 5.2 | 2.0e-07 | -0.87 | 0.04 | 0.58 | FALSE |
| 3 | GTEx | Esophagus Muscularis | MGAT3 | 0.09 | 0.02 | enet | 15 | 0.02 | 1.3e-02 | -4.2 | 5.3 | 1.4e-07 | -0.46 | 0.10 | 0.55 | TRUE |
| 4 | GTEx | Heart Atrial Appendage | MGAT3 | 0.14 | 0.14 | lasso | 2 | 0.12 | 3.5e-06 | -5.5 | 5.5 | 4.5e-08 | -0.97 | 0.02 | 0.98 | FALSE |
| 5 | GTEx | Nerve Tibial | TAB1 | 0.15 | 0.13 | lasso | 5 | 0.15 | 1.0e-10 | -5.2 | -5.2 | 1.8e-07 | 0.85 | 0.07 | 0.93 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | MGAT3 | 0.13 | 0.05 | lasso | 3 | 0.02 | 4.7e-03 | -5.5 | 5.3 | 9.8e-08 | -0.96 | 0.02 | 0.96 | FALSE |