TWAS hub - MGAT3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0380	0.018	7.2e-03	-0.002	0.002	-0.002	0	-0.002	8.5e-01	1.9e-01	6.1e-01	0.33	7.1e-01
2	GTEx	Adipose Subcutaneous	0.0790	0.035	3.0e-03	0.041	NA	0.037	NA	0.038	2.8e-04	NA	4.8e-04	NA	4.3e-04
3	GTEx	Breast Mammary Tissue	0.1460	0.059	2.2e-03	0.005	NA	-0.006	NA	0.003	1.7e-01	NA	9.9e-01	NA	2.3e-01
4	GTEx	Breast Mammary Tissue (Female)	0.2549	0.093	9.4e-04	-0.008	NA	0.021	NA	-0.009	6.9e-01	NA	7.9e-02	NA	7.7e-01
5	GTEx	Esophagus Muscularis	0.0910	0.036	1.6e-03	0.024	NA	0.024	NA	0.014	1.3e-02	NA	1.3e-02	NA	4.5e-02
6	GTEx	Heart Atrial Appendage	0.1360	0.055	1.1e-03	0.143	NA	0.091	NA	0.124	5.7e-07	NA	6.7e-05	NA	3.5e-06
7	GTEx	Skin Sun Exposed Lower leg	0.1330	0.049	4.3e-04	0.049	NA	0.010	NA	0.023	6.7e-05	NA	4.7e-02	NA	4.7e-03
8	GTEx	Testis	0.4720	0.085	2.9e-10	0.473	NA	0.437	NA	0.082	2.0e-23	NA	3.8e-21	NA	1.6e-04
9	TCGA	Cervical Squamous Cell Carcinoma	0.2870	0.112	6.7e-03	0.015	0.002	0.066	NA	0.062	6.1e-02	2.6e-01	3.5e-04	NA	5.6e-04
10	TCGA	Brain Lower Grade Glioma	0.0387	0.018	3.5e-05	0.013	0.040	0.036	NA	0.017	1.1e-02	2.3e-05	5.5e-05	NA	4.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Intelligence (Savage-Jansen 2018)	12.6	38.7	54.1	6.4	7.0	6.4	4.5	7.3	7.2	7.0	-4.8	1.7	7.4
Verbal and Numeric Reasoning (VNR)	11.8	28.2	45.1	5.6	5.7	5.2	3.0	6.7	5.7	5.6	-4.5	3.1	6.6
Fluid intelligence score	11.3	23.5	30.4	4.8	5.5	5.2	3.5	5.3	5.5	5.3	-4.3	3.5	5.1
Schizophrenia (2014)	7.0	15.5	40.3	-3.9	-3.3	-2.7	-3.3	-6.4	-3.1	-3.1	5.2	-1.6	-4.6
Schizophrenia (2018)	6.6	13.6	32.7	-3.8	-3.3	-2.8	-3.3	-5.7	-3.1	-3.1	4.5	-0.5	-4.4
Qualifications: College or University degree	5.8	18.3	26.3	4.3	4.8	4.3	2.8	5.1	4.9	4.9	-4.1	3.2	3.6
Prospective memory result	5.6	6.8	13.2	-1.9	-2.4	-2.3	-1.2	-3.3	-2.5	-2.5	3.6	-1.6	-3.5
Worry too long after embarrassment	5.5	9.3	21.6	4.3	2.6	2.5	2.1	3.6	2.2	2.3	-3.2	1.3	4.7
Average weekly beer plus cider intake	5.4	7.9	14.6	-3.0	-2.7	-2.5	-0.5	-3.8	-2.7	-2.7	3.3	-1.9	-3.4
Chest pain or discomfort	4.6	6.6	11.3	2.2	3.2	3.0	2.2	1.4	3.3	3.4	-2.5	1.0	2.5
Bipolar Disorder or Schizophrenia	4.5	11.1	33.6	-2.8	-2.7	-2.3	-3.9	-5.8	-2.5	-2.5	3.6	-0.6	-3.9
Noisy workplace	4.5	5.5	12.0	-3.5	-2.3	-2.7	-1.4	-1.4	-2.6	-2.6	2.2	-1.4	-2.5
Qualifications: A levels/AS levels or equivalent	4.4	9.8	17.7	3.5	2.5	2.3	3.6	4.2	2.5	2.6	-3.5	2.2	3.7
Medication: Paracetamol	4.0	6.6	13.8	-3.7	-3.1	-2.6	-2.8	-1.6	-2.9	-2.8	1.7	-0.9	-2.3
Medication for pain relief, constipation, heartburn	4.0	6.8	14.5	3.8	3.3	3.1	2.5	1.6	2.9	2.7	-2.2	0.6	1.7
Guilty feelings	3.9	5.9	21.0	3.2	0.5	0.5	2.8	2.4	0.1	0.0	-3.4	1.6	4.6
Trunk fat-free mass	3.8	21.9	35.5	4.9	5.6	4.9	2.0	5.2	6.0	5.9	-3.3	1.3	5.1
Trunk predicted mass	3.8	22.0	35.9	4.9	5.6	4.9	1.9	5.2	6.0	5.9	-3.3	1.3	5.1
Qualifications: O levels/GCSEs or equivalent	3.8	6.1	15.0	2.5	1.8	1.5	3.0	3.9	1.9	1.8	-2.8	0.9	3.1
Waist Hip Ratio (WHR)	3.7	16.8	27.9	-3.0	-4.8	-3.9	-2.0	-4.5	-5.3	-5.3	3.9	-3.5	-3.6
Medication: Lansoprazole	3.6	4.1	8.3	-1.6	-1.9	-2.0	-2.9	-2.1	-1.6	-1.5	2.4	-1.3	-2.5
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.5	8.4	-2.9	-2.3	-2.5	-1.2	-1.9	-2.0	-2.1	1.9	-0.2	-2.8
Whole body fat-free mass	3.5	20.0	34.5	4.6	5.5	4.6	1.5	5.0	5.9	5.9	-3.0	1.2	4.6
Friendships satisfaction	3.5	4.3	7.4	1.8	2.6	2.0	2.1	1.0	2.7	2.6	-1.4	1.9	1.9
Whole body water mass	3.5	19.8	34.4	4.6	5.5	4.6	1.6	4.9	5.9	5.8	-3.0	1.2	4.5
Arm fat-free mass (left)	3.5	17.5	32.0	3.8	5.4	4.7	1.0	4.4	5.7	5.7	-2.4	1.0	4.4
Arm predicted mass (left)	3.4	17.5	31.0	3.9	5.3	4.8	1.0	4.5	5.6	5.6	-2.4	1.0	4.5
Qualifications: None of the above	3.3	7.1	13.8	-3.3	-2.6	-2.5	-1.2	-3.3	-2.5	-2.5	3.7	-2.1	-2.0
Leg predicted mass (right)	3.3	17.5	32.4	4.4	5.3	4.2	1.3	4.5	5.6	5.7	-2.7	1.4	3.8
Basal metabolic rate	3.3	18.1	33.4	4.1	5.4	4.5	0.8	4.6	5.8	5.8	-2.7	1.0	4.2
Ulcerative Colitis	3.2	4.6	8.2	2.1	2.1	2.5	-1.0	2.9	1.8	1.8	-2.4	1.8	2.7
Leg predicted mass (left)	3.2	16.8	31.7	4.0	5.2	4.1	0.9	4.6	5.6	5.6	-2.7	1.3	3.8
Medication: Ibuprofen	3.2	3.8	8.1	-2.7	-1.7	-1.9	-1.9	-1.8	-1.5	-1.5	2.2	0.0	-2.8
Leg fat-free mass (right)	3.2	17.1	31.8	4.3	5.2	4.2	1.3	4.5	5.6	5.6	-2.6	1.4	3.8
Medication for hormone replacement therapy	3.1	3.4	6.7	-1.2	-2.3	-2.6	-0.9	-2.1	-2.3	-2.4	0.6	-1.0	-1.7
Leg fat-free mass (left)	3.1	16.3	30.9	3.9	5.1	4.1	0.8	4.4	5.5	5.6	-2.6	1.2	3.8
Commuting to job workplace: Walk	3.1	3.4	7.8	2.8	1.8	1.6	1.2	1.6	1.9	1.8	-1.8	1.1	2.2
Lupus	2.9	4.4	11.5	-1.6	-1.1	-0.5	-0.7	-2.3	-1.7	-1.7	3.4	-3.2	-2.6
Arm fat-free mass (right)	2.9	15.0	25.6	3.6	4.9	4.2	1.5	4.3	5.1	5.1	-2.3	0.8	4.2
Arm predicted mass (right)	2.9	15.0	25.4	3.7	4.9	4.3	1.4	4.5	5.0	5.0	-2.2	0.7	4.1
Schizophrenia vs Biploar Disorder	2.8	3.7	10.4	-2.0	-1.1	-0.8	-1.1	-2.5	-1.0	-1.0	3.2	-2.4	-2.3
Primary Biliary Cirrhosis	2.8	3.9	13.2	-0.3	0.1	0.3	-3.1	-2.4	0.1	0.2	3.6	-1.3	-3.0
Medication for cholesterol	2.8	4.3	7.8	2.3	2.5	2.8	1.5	1.4	2.6	2.5	-1.6	-0.4	1.9
Reaction Time	2.7	5.2	13.2	-2.7	-1.2	-0.8	-2.3	-2.9	-1.7	-1.7	3.6	-2.3	-2.1
Rheumatoid Arthritis	2.7	3.7	13.9	-0.5	-2.0	-1.8	-3.7	-2.1	-1.8	-1.9	1.0	-1.3	-1.0
Blood White Count	2.7	19.7	44.0	-5.5	-4.0	-3.6	-6.6	-5.4	-3.1	-3.1	4.3	-2.4	-4.5
Irritable Bowel Disease (IBD)	2.6	6.2	15.4	2.4	3.0	3.9	-3.5	2.0	2.2	2.2	-0.8	1.6	1.5
Hearing aid user	2.5	2.8	6.0	0.1	1.8	1.3	1.3	2.5	1.5	1.4	-2.5	1.4	1.6
Commuting to job workplace: Public transport	2.5	3.0	8.0	1.1	0.5	0.5	2.8	2.7	0.5	0.5	-2.0	1.0	2.7
Alcohol drinker status: Previous	2.5	2.9	11.4	2.5	0.5	0.7	1.2	2.3	0.6	0.6	-1.6	0.7	3.4
Alzheimer’s Disease (in father)	2.4	2.6	4.5	-2.1	-1.9	-1.4	-1.2	-1.7	-1.9	-1.9	1.5	0.0	-1.3
Illness, injury, bereavement, stress in last 2 years	2.4	2.9	5.1	1.1	2.2	2.3	1.9	1.4	2.2	2.1	-0.4	0.7	1.6
Mouth/teeth dental problems: Mouth ulcers	2.4	3.9	14.3	2.2	1.5	1.6	3.8	0.4	1.2	1.1	-2.4	1.7	1.8
Commuting to job workplace: Cycle	2.4	2.9	4.9	1.8	2.1	1.9	0.5	1.8	2.2	2.1	-1.6	1.0	1.3
Height	2.3	44.8	68.4	8.1	7.8	7.2	4.4	6.0	8.3	8.0	-5.3	3.2	6.7
Number of treatments/medications taken	2.3	4.2	11.3	-2.5	-2.3	-2.5	-3.4	-0.5	-2.2	-2.1	1.2	0.4	-1.2
Comparative body size at age 10	2.3	6.3	13.1	2.4	2.5	1.7	0.9	3.6	2.9	2.9	-2.3	2.0	2.8
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.4	5.3	-1.5	-2.0	-1.7	-2.3	-0.9	-1.7	-1.6	1.1	-0.5	-1.6
Risk taking	2.3	3.3	11.4	-2.1	-0.8	-0.2	-0.1	-2.0	-1.1	-1.1	2.1	-2.5	-3.4
HbA1C	2.2	2.4	7.7	-1.3	-1.3	-2.2	0.0	-0.9	-2.1	-2.8	1.3	-0.8	-1.0
Diabetes (mother)	2.2	2.8	5.9	-1.5	-1.5	-1.7	-0.2	-2.4	-1.5	-1.5	2.3	-1.8	-1.4
Had other major operations	2.2	2.7	4.5	-2.1	-1.7	-1.3	-1.1	-1.9	-1.7	-1.6	1.8	-0.8	-2.0
Hip circumference	2.2	9.5	19.4	2.3	3.7	3.0	-1.2	3.4	4.2	4.4	-2.3	0.9	3.2
Lung cancer (father)	2.2	2.6	6.6	2.4	1.6	1.6	-0.2	1.0	1.6	1.5	-1.4	0.6	2.6
Ulcerative Colitis (UC)	2.1	4.0	12.0	1.7	2.1	2.6	-3.5	2.3	1.6	1.6	-0.9	0.7	1.5
Financial difficulties in last 2 years	2.1	2.9	7.0	-1.0	-2.3	-2.6	-2.3	-1.2	-2.0	-1.9	-0.0	-1.1	-0.4
Medication: Paracetamol	2.1	3.3	8.6	-2.5	-2.2	-1.5	-2.9	-1.0	-2.0	-2.0	0.8	0.1	-1.2
Pain all over the body in last month	2.0	2.2	4.1	-1.6	-2.0	-1.5	-1.6	-0.3	-2.0	-1.9	0.9	-0.5	-1.1
Standing height	2.0	20.2	38.4	6.2	5.0	4.5	2.9	4.0	5.2	5.1	-4.0	0.9	4.9
Birth weight of first child	2.0	3.6	6.7	1.4	2.6	1.9	2.4	1.4	2.6	2.4	-0.7	0.6	1.7
Gout (self-reported)	2.0	2.8	4.3	-1.7	-1.8	-2.0	-1.0	-1.1	-1.9	-1.8	2.0	-0.5	-2.1
Stomach or abdominal pain in last month	1.9	2.3	5.1	1.1	0.8	1.3	1.6	2.0	0.8	0.8	-2.1	1.5	2.3
Impedance of leg (left)	1.9	9.3	16.2	-2.9	-3.6	-2.4	-1.7	-3.9	-4.0	-4.0	2.2	-2.5	-2.2
Weight	1.9	9.3	21.5	2.3	4.0	3.2	-1.5	3.0	4.5	4.6	-1.4	0.2	2.5
Illnesses of siblings: Diabetes	1.9	2.3	5.7	1.4	2.4	1.9	-0.4	1.0	2.2	2.1	0.3	0.8	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	4.0	-1.5	-1.2	-1.0	-1.3	-1.9	-1.2	-1.2	1.9	-1.3	-2.0
Crohns Disease (2012)	1.8	3.0	11.2	1.6	2.5	3.3	-0.9	0.5	1.9	1.9	0.1	0.2	1.0
Impedance of leg (right)	1.8	8.7	15.3	-3.0	-3.6	-2.5	-1.9	-3.6	-3.9	-3.9	1.7	-2.3	-1.9
Medication: Ramipril	1.8	2.4	6.9	-1.0	-1.4	-1.0	-0.3	-1.0	-1.8	-1.7	2.6	-1.9	-1.4
Alzheimer’s Disease (in mother)	1.7	1.9	7.0	2.6	1.3	1.3	0.1	1.5	1.2	1.2	-1.3	0.3	1.4
Qualifications: CSEs or equivalent	1.7	2.3	6.0	-1.8	-0.3	-0.5	-0.6	-2.4	-0.5	-0.4	1.6	-2.4	-2.1
Father’s age at death	1.7	2.3	4.6	1.5	1.7	1.4	-0.3	1.4	2.1	2.1	-1.5	0.4	1.6
Wears glasses or contact lenses	1.7	1.9	4.3	1.1	1.0	1.5	0.8	1.4	1.0	1.0	-2.0	2.1	1.5
Relative age voice broke	1.6	2.4	6.9	1.1	1.4	2.0	2.6	-0.5	1.6	1.5	-1.3	1.3	1.1
Heart disease (siblings)	1.6	1.9	4.0	-1.2	-1.8	-2.0	0.8	-1.8	-1.6	-1.8	0.9	-0.3	-0.5
Impedance of whole body	1.6	8.0	14.3	-2.6	-3.3	-2.6	-1.5	-3.8	-3.5	-3.4	1.8	-1.9	-3.0
Ovarian Cancer	1.5	2.0	5.0	1.4	1.9	1.3	0.2	0.4	2.2	2.2	-0.6	1.1	1.4
Hand grip strength (left)	1.5	3.9	8.1	2.2	2.8	2.8	-0.3	0.6	2.8	2.7	-0.5	-0.3	1.4
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.4	-0.8	-1.5	-2.1	-0.5	-1.1	-1.0	-1.0	1.2	-1.6	-1.0
Sitting height	1.5	10.7	19.3	3.8	3.3	3.3	2.5	4.4	3.4	3.3	-2.7	1.1	3.8
Number of incorrect matches in round	1.5	2.4	4.7	-1.2	-2.0	-2.2	-1.0	-1.9	-1.9	-2.0	0.6	-0.6	-0.9
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	7.0	-0.4	0.8	1.3	-1.9	-1.4	0.5	0.5	2.0	-2.6	-0.3
Forced expiratory volume in 1-second (FEV1)	1.5	5.0	8.8	2.0	3.0	2.8	1.8	1.4	2.9	2.8	-2.1	0.7	1.8
Medication: Omeprazole	1.5	1.8	6.2	1.3	0.1	0.1	-0.1	2.1	0.4	0.5	-1.5	2.5	1.7
Commuting to job workplace: Car/motor vehicle	1.5	1.7	6.8	-1.0	-0.3	-0.3	-2.5	-1.5	-0.3	-0.4	0.7	0.6	-2.6
Basal cell carcinoma (self-reported)	1.5	1.8	6.2	1.2	0.2	0.5	1.2	2.2	0.2	0.2	-2.5	1.4	1.4
Crohns Disease (2017)	1.4	3.0	11.4	1.7	2.4	3.4	-1.8	0.7	1.6	1.6	0.6	0.8	0.5
High blood pressure (mother)	1.4	2.0	5.1	-2.3	-1.7	-1.8	-0.6	-0.7	-1.7	-1.7	-0.4	0.6	-1.3
Forced vital capacity (FVC)	1.4	5.2	7.4	2.1	2.6	2.2	2.7	1.6	2.7	2.5	-2.6	0.8	2.3
Impedance of arm (right)	1.4	6.3	11.4	-2.1	-2.9	-2.7	-1.9	-3.4	-2.6	-2.6	1.3	-1.1	-3.3
Birth weight	1.4	3.0	6.9	1.9	2.5	2.1	1.0	1.1	2.6	2.6	-0.2	-0.0	0.5
Forced vital capacity (FVC), Best measure	1.4	5.2	9.3	2.1	2.5	2.1	3.1	1.4	2.6	2.4	-2.5	0.6	2.6
Loneliness, isolation	1.4	2.0	5.3	-1.2	-1.7	-2.3	0.2	-1.7	-1.7	-1.8	0.9	0.4	0.3
Average weekly champagne plus white wine intake	1.4	1.9	3.2	0.1	1.8	1.2	0.8	1.2	1.8	1.7	-1.7	1.5	1.0
Chronotype (morning person)	1.3	2.9	8.7	-0.4	1.6	2.0	-1.9	-2.9	1.4	1.5	2.2	0.6	-1.0
Hand grip strength (right)	1.3	3.5	7.5	2.2	2.7	2.7	-0.5	0.2	2.5	2.3	-0.9	0.1	1.7
Mean time to correctly identify matches	1.3	2.5	9.1	-1.5	-0.3	-0.4	-1.4	-2.5	-0.7	-0.8	3.0	-1.7	-1.1
Comparative height size at age 10	1.3	7.1	18.1	4.3	3.0	2.9	0.8	2.4	3.1	3.0	-1.9	0.1	2.5
Age started oral contraceptive pill	1.3	1.6	3.1	0.2	1.4	1.1	0.8	1.3	1.7	1.5	-1.2	1.8	0.9
Neuroticism (2016)	1.2	1.7	3.6	-0.0	-1.5	-1.9	-0.9	-0.3	-1.4	-1.3	-1.7	1.1	1.7
Average weekly fortified wine intake	1.2	1.4	3.8	2.0	0.8	0.8	1.1	1.2	0.6	0.6	-1.3	1.0	1.7
Fed-up feelings	1.2	2.3	3.9	-2.0	-1.8	-1.8	-1.1	-1.7	-2.0	-1.8	0.9	-0.5	0.6
Serious illness, injury or assault to yourself	1.2	1.4	5.3	-0.7	-0.5	-0.5	-2.3	-1.5	-0.4	-0.4	1.1	-0.9	-1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.8	6.3	1.9	2.5	2.3	2.0	1.0	2.5	2.3	-1.8	0.6	1.8
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.9	-0.3	1.1	1.5	-1.7	-0.0	0.9	0.9	1.2	-1.6	-1.4
High blood pressure (siblings)	1.2	1.8	5.9	0.2	1.0	-0.2	1.0	2.1	1.1	1.2	-2.4	0.9	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.1	-1.0	-1.0	-1.1	-1.1	-1.8	-0.7	-0.7	0.8	-1.6	-1.7
Ever had bowel cancer screening	1.2	1.4	2.5	1.6	1.0	1.5	-0.8	1.6	1.2	1.1	-0.8	0.2	1.3
Medication: Aspirin	1.2	1.5	3.3	-1.8	-1.5	-1.7	-1.6	0.1	-1.4	-1.3	0.9	-0.3	0.1
Illnesses of siblings	1.1	1.5	3.6	-0.9	-1.2	-0.2	-1.5	-1.2	-1.2	-1.2	1.5	-0.8	-1.9
Smoking status: Current	1.1	1.8	4.0	-0.8	-1.7	-2.0	-0.7	-1.1	-1.4	-1.5	1.1	-1.4	-0.9
Depressed Affect (Nagel 2018)	1.0	2.1	6.2	-1.2	-1.1	-1.3	-2.4	-2.5	-1.1	-1.0	1.4	-0.1	-0.6
Type 2 Diabetes (T2D) (2012)	1.0	1.1	1.8	-1.0	1.2	1.3	-1.2	-0.8	1.1	1.1	1.0	-1.1	0.1
Maternal smoking around birth	1.0	1.4	3.6	-0.4	-1.4	-1.1	-0.4	0.4	-1.8	-1.9	0.9	-1.0	-1.4
Age when periods started (menarche)	1.0	2.5	4.6	-1.4	-2.1	-2.1	-1.4	-1.3	-1.9	-2.0	0.8	-0.6	-1.3
Medication: Atenolol	1.0	1.2	3.8	-1.7	-0.6	-0.7	-0.6	-1.2	-0.6	-0.5	1.4	-2.0	-0.7
Impedance of arm (left)	1.0	4.7	8.2	-1.5	-2.6	-2.5	-1.2	-2.8	-2.4	-2.4	1.1	-1.2	-2.9
Arm fat mass (right)	1.0	3.9	10.3	0.4	2.5	1.9	-2.6	1.5	3.0	3.2	-0.0	-0.5	0.9
Length of working week for main job	1.0	1.1	2.0	0.2	1.3	0.9	-1.4	0.5	1.4	1.4	-0.1	-1.4	0.3
Peak expiratory flow (PEF)	1.0	2.3	5.7	1.3	2.2	2.4	0.6	0.8	2.1	2.0	-0.9	-0.2	0.6
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	10.6	-0.1	0.0	-0.7	-3.3	-0.9	0.2	0.4	1.6	-1.4	-1.5
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.7	1.7	1.0	1.5	-0.3	0.0	1.1	1.2	-0.6	1.4	1.3
Number of full brothers	1.0	1.2	2.4	0.4	1.4	1.1	-0.7	0.4	1.5	1.6	-0.9	1.5	0.8
Medication: Allopurinol	1.0	1.3	3.1	-1.1	-0.9	-1.6	-1.1	-0.6	-0.8	-0.6	1.8	-0.5	-1.7
Overall health rating	1.0	2.2	5.2	-2.3	-1.7	-2.2	-1.0	-1.1	-1.5	-1.4	1.4	-0.2	-1.1
Family relationship satisfaction	1.0	1.3	8.7	-0.1	-0.2	-0.4	0.3	-0.5	0.1	0.0	-1.8	3.0	0.3
Knee pain experienced in last month	1.0	1.5	3.5	-1.1	-1.0	-0.9	-1.5	-0.6	-0.9	-1.0	1.9	-1.6	-1.2
Illnesses of father: Heart disease	1.0	1.3	7.0	0.2	-0.3	0.4	-0.1	1.6	-0.5	-0.6	-1.5	2.6	1.0
Mother’s age at death	1.0	1.2	4.1	0.3	1.0	1.2	1.3	2.0	1.2	1.2	0.1	-0.1	1.0
Financial situation satisfaction	1.0	1.2	2.5	-1.3	-1.1	-1.4	-1.6	-1.0	-1.1	-1.2	0.4	-0.3	-0.7
Supplements: Calcium	1.0	1.1	4.4	0.1	0.0	-0.4	1.4	0.7	0.1	0.2	-2.1	1.4	1.3
Frequency of depressed mood in last 2 weeks	0.9	1.3	3.4	-0.8	-1.6	-1.8	-1.2	-0.5	-1.4	-1.4	0.3	0.6	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	4.1	-1.1	-1.5	-1.5	-2.0	-1.6	-1.3	-1.4	1.2	0.2	-1.7
Heart attack	0.9	1.1	5.8	-1.0	-0.3	0.1	-0.4	-0.4	-0.5	-0.4	2.4	-1.3	-1.4
Medication: Simvastatin	0.9	1.3	5.6	-1.4	-0.5	0.1	0.2	-0.2	-1.2	-1.3	2.4	-1.4	0.3
Pulse rate	0.9	1.5	4.3	-0.6	-1.4	-1.7	0.2	0.1	-1.5	-1.5	0.8	-2.1	0.1
Mouth/teeth dental problems: Dentures	0.9	1.5	5.7	0.5	1.1	1.2	-2.4	-0.5	1.7	1.6	0.5	0.2	0.6
Illnesses of mother	0.9	1.2	2.6	1.6	1.1	1.4	-0.2	0.9	1.2	1.2	0.9	-0.8	0.7
Exposure to tobacco smoke at home	0.9	1.0	2.3	0.1	1.4	1.2	-0.7	-0.6	1.5	1.5	0.9	-0.5	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	5.6	1.5	1.0	1.4	-0.9	-0.1	0.9	0.8	-0.8	0.6	2.4
Blood clot in the leg (DVT)	0.9	1.2	3.2	-0.5	-0.6	-0.6	1.8	-1.3	-1.1	-1.1	1.1	-0.8	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.4	-0.0	-1.6	-1.5	-0.1	1.1	-1.5	-1.3	-0.7	0.1	0.2
Medication: Aspirin	0.9	1.2	3.1	-1.8	-1.4	-1.5	-1.3	-0.3	-1.2	-1.2	0.6	0.3	0.0
Handedness (chirality/laterality): Left-handed	0.9	1.0	7.8	0.4	0.2	0.4	0.4	0.6	0.1	0.1	1.3	-2.8	0.2
Mood swings	0.9	1.6	5.0	-2.2	-1.3	-1.1	-1.4	-2.0	-1.2	-1.0	0.1	0.2	0.4
Pain experienced in last month	0.9	1.5	4.7	1.9	0.6	0.4	2.2	0.5	0.5	0.5	-2.0	0.9	0.9
Fasting Glucose	0.8	0.9	5.1	-0.2	0.2	0.3	-0.5	-1.4	-0.1	0.1	2.3	-0.7	-1.1
Heel T-Score	0.8	6.5	13.2	-0.8	-3.6	-3.0	-2.2	-1.1	-3.5	-3.5	2.3	-0.5	-2.4
Hypothyroidism (self reported)	0.8	1.9	9.8	0.8	0.6	-0.1	-3.1	-0.7	0.6	0.9	1.6	-1.6	-1.2
Supplements: Glucosamine	0.8	1.0	2.9	0.2	-1.2	-0.9	0.5	0.3	-1.4	-1.4	-0.4	1.0	-1.7
Alcohol usually taken with meals	0.8	1.4	6.1	0.5	0.3	-0.1	1.9	2.5	0.5	0.4	-1.6	0.9	0.2
Had menopause	0.8	1.0	2.2	0.6	1.1	1.4	0.7	0.8	1.2	1.2	-0.3	0.7	1.5
Ever highly irritable/argumentative for 2 days	0.8	1.0	5.5	-0.5	0.3	0.5	-0.8	-2.3	0.1	0.1	1.7	-0.3	-0.1
Medication: Blood pressure	0.8	1.4	3.5	-1.9	-0.9	-1.0	-1.7	1.1	-1.2	-1.1	0.7	-0.9	0.4
Heart disease (mother)	0.8	1.0	3.9	-0.6	0.3	0.2	1.2	0.5	0.6	0.5	-2.0	1.7	0.3
Supplements: Vitamin C	0.8	1.0	4.4	0.5	-0.1	0.1	-2.1	-1.5	0.1	0.1	1.2	0.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.1	0.9	1.4	1.1	1.8	0.7	1.5	1.6	-1.0	-0.5	1.6
Qualifications: nursing, teaching	0.8	1.2	3.6	1.7	0.6	0.0	0.5	1.4	1.0	0.8	-1.9	0.9	-0.2
Breast cancer (self-reported)	0.8	1.0	2.6	0.8	1.3	1.5	-0.0	-0.2	1.6	1.6	-0.2	0.5	-0.1
Arm fat mass (left)	0.8	3.4	9.0	0.2	2.3	1.7	-2.4	1.4	2.8	3.0	0.1	-0.6	0.7
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.2	-0.8	-1.2	-0.5	-1.0	-0.2	-1.5	-1.5	-0.3	1.2	-0.0
Cholesterol lowering medication	0.8	1.2	2.8	-0.9	-1.6	-1.3	-0.3	-0.5	-1.7	-1.7	1.0	0.2	0.1
Heart attack/myocardial infarction (self-reported)	0.8	1.0	5.3	-0.9	-0.2	0.3	-0.4	-0.4	-0.4	-0.2	2.3	-1.4	-1.2
Bipolar Disorder (2018)	0.7	1.1	5.7	0.3	-0.1	-0.2	-2.4	-2.1	-0.1	-0.1	0.3	-0.4	-0.7
Breast Cancer	0.7	1.6	5.9	-1.2	-1.6	-1.4	-2.4	-0.3	-1.4	-1.0	-0.2	0.3	-1.0
Bipolar Disorder (2011)	0.7	0.7	3.9	0.5	-0.6	-0.8	-2.0	-1.1	-0.2	-0.1	0.2	0.0	-0.5
Coronary Artery Disease (CAD)	0.7	0.8	1.4	-0.4	-1.0	-1.2	0.5	-0.7	-1.2	-1.1	0.9	-1.1	-0.5
Hearing difficulty/problems: Yes	0.7	1.1	5.3	-0.1	0.4	0.3	0.7	2.0	0.4	0.4	-0.3	-2.3	-0.1
Medication: Levothyroxine sodium	0.7	1.2	3.2	0.8	1.4	0.7	-1.8	0.0	1.4	1.7	0.5	-0.3	-0.5
Nervous feelings	0.7	1.2	2.8	-0.2	-1.6	-1.2	0.0	-1.5	-1.7	-1.7	0.4	0.5	0.1
Neuroticism score	0.7	1.5	11.2	0.4	-0.4	-0.4	0.7	-0.6	-0.7	-0.7	-1.0	0.5	3.3
Arm fat percentage (right)	0.7	2.6	14.5	-1.5	0.8	0.4	-3.8	-0.5	1.3	1.6	1.3	-1.0	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.4	-1.6	-1.5	-1.5	-0.3	-1.2	-1.2	-1.0	0.2	0.6	-0.5
Medication: Amlodipine	0.7	1.0	3.4	-1.8	-0.4	-0.4	-0.1	-0.3	-0.7	-0.6	1.8	-1.4	-0.2
Leg fat percentage (right)	0.7	2.5	16.2	-1.9	0.5	0.6	-4.0	-0.6	0.8	1.0	1.1	-1.3	0.1
Medication: Seretide 50 evohaler	0.7	0.8	3.3	0.4	0.1	-0.3	1.1	0.1	0.1	0.2	-1.8	0.5	1.6
Leg fat mass (right)	0.7	2.6	7.1	-0.3	1.8	1.5	-2.7	1.0	2.1	2.3	0.0	-0.8	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.6	0.9	-0.9	-1.1	1.1	1.1	-0.6	-0.6	-0.7	-0.5	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.6	1.0	-0.7	-1.0	1.3	1.1	-0.9	-0.8	-0.8	0.4	0.0
Medication: Blood pressure	0.7	1.3	5.3	-2.3	-0.9	-1.0	-1.5	-0.6	-0.8	-0.7	0.9	0.3	-1.3
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.7	0.6	-1.3	-1.1	0.0	-1.3	-1.0	-0.9	-0.5	0.7	-1.2
High cholesterol (Self-reported)	0.7	1.2	5.6	-2.4	-0.5	-0.5	1.3	0.4	-1.1	-1.1	0.8	-0.5	1.1
Leg fat percentage (left)	0.7	2.6	16.6	-1.7	0.6	0.7	-4.1	-0.7	0.8	1.0	1.3	-1.3	-0.0
Myopia	0.7	1.0	4.0	0.1	-0.4	-0.3	2.0	0.9	-0.3	-0.2	-1.9	1.1	-0.5
Leg fat mass (left)	0.7	2.7	7.2	-0.2	1.9	1.6	-2.7	0.8	2.2	2.3	0.2	-0.9	1.1
Prostate Cancer	0.6	0.9	3.0	-0.2	-0.5	-0.5	0.7	0.5	-0.2	-0.2	-1.6	1.7	1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.6	0.6	-0.0	0.2	-1.2	-1.1	-0.5	-0.4	1.9	-1.0	-1.9
Current tobacco smoking	0.6	1.0	2.5	-0.8	-1.2	-1.6	-0.7	-0.8	-0.9	-1.0	0.8	-1.1	-0.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.5	0.7	-0.8	-0.3	-0.5	1.2	-1.1	-1.1	-0.5	1.0	0.3
Chronic bronchitis/emphysema (father)	0.6	0.7	1.3	-0.7	-0.8	-1.1	0.8	-0.9	-0.8	-0.7	0.7	-1.0	-0.3
Body mass index (BMI)	0.6	2.6	7.9	-0.5	1.9	1.2	-2.8	1.3	2.3	2.4	0.5	-0.3	0.5
Trunk fat mass	0.6	2.8	8.3	0.3	1.9	1.4	-2.9	0.7	2.4	2.6	0.1	-0.8	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	9.4	-0.1	-0.6	-0.8	-3.1	-1.5	-0.3	-0.4	0.6	0.9	-0.7
Depression (self-reported)	0.6	0.7	5.9	-0.5	-0.2	0.1	-2.4	-1.0	-0.2	-0.2	-0.4	-0.2	0.2
Pulse wave Arterial Stiffness index	0.6	0.6	2.4	0.5	0.7	1.6	1.5	0.0	0.2	0.1	-0.1	-0.9	0.2
Body fat percentage	0.6	2.3	14.6	-1.2	0.8	0.4	-3.8	-0.4	1.2	1.5	0.9	-1.1	-0.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.8	-0.8	-0.9	-1.1	-0.8	1.7	-0.3	-0.3	0.0	0.7	-0.9
Whole body fat mass	0.6	2.7	7.5	-0.0	1.9	1.4	-2.7	1.0	2.3	2.5	0.0	-0.6	0.8
Had major operations	0.6	0.7	5.2	-0.0	0.2	-0.2	2.3	-0.9	0.4	0.4	0.2	0.7	0.2
Arm fat percentage (left)	0.6	2.3	12.6	-1.4	0.7	0.2	-3.6	-0.3	1.2	1.5	1.3	-1.1	-1.0
Osteoarthritis (self-reported)	0.6	0.8	2.3	-1.1	-1.0	-1.5	-0.3	-0.6	-0.7	-0.7	0.5	-0.4	-1.4
Alcohol drinker status: Never	0.6	0.7	2.0	1.4	0.7	0.8	0.4	1.3	0.9	1.0	-0.2	0.5	0.4
Diastolic blood pressure, automated reading	0.6	2.0	3.1	-0.5	1.7	1.6	0.0	1.8	1.5	1.4	-1.6	1.4	1.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	8.1	2.8	0.2	-0.1	1.9	-0.1	0.5	0.4	-1.7	0.5	0.3
Depression (Nagel 2018)	0.5	0.7	1.8	-0.2	-1.0	-1.3	-0.8	-1.3	-0.8	-0.7	-0.2	0.8	-0.0
Major Depression (MDD)	0.5	0.7	4.0	-0.3	-0.7	-0.5	-2.0	-1.0	-0.6	-0.5	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.5	0.7	3.4	-0.1	0.8	0.6	-1.8	0.2	0.9	1.0	-0.1	-1.1	-0.3
Neuroticism	0.5	1.1	8.6	0.8	0.3	0.4	-0.4	-0.9	-0.1	0.1	-0.8	-0.5	2.9
Sensitivity / hurt feelings	0.5	0.9	3.1	1.1	-0.7	-0.3	0.3	-0.2	-1.2	-0.9	-1.3	-0.6	1.8
Diabetes (father)	0.5	0.7	1.7	-0.6	-0.5	0.3	-0.4	-1.2	-0.5	-0.5	1.1	-1.3	-1.0
Trunk fat percentage	0.5	2.1	13.5	-0.7	0.8	0.4	-3.7	-0.5	1.3	1.5	0.9	-1.1	-0.6
High blood pressure	0.5	1.4	8.6	-2.9	-0.4	-0.4	-1.8	0.5	-0.5	-0.4	1.1	0.0	-0.4
Hair/balding pattern: Pattern 2	0.5	0.6	2.8	0.3	0.2	-0.4	-0.6	-1.1	0.1	0.2	-1.0	1.7	0.2
Mouth/teeth dental problems	0.5	0.7	2.3	-0.9	-0.7	-0.7	-0.1	1.5	-1.1	-1.1	0.5	-0.6	-0.2
Alcohol intake versus 10 years previously	0.5	0.8	1.7	-1.3	-0.8	-1.1	0.7	-0.7	-0.6	-0.6	-0.2	-0.8	1.3
Number of live births	0.5	0.7	5.4	0.2	0.1	0.1	-0.9	-0.4	0.1	0.1	2.3	-0.6	-0.6
Medication: Cholesterol lowering	0.5	0.8	2.2	-0.8	0.7	1.0	0.3	1.3	-0.0	-0.1	0.8	-1.1	1.5
Pulse wave reflection index	0.5	0.6	2.6	0.4	0.5	1.1	-0.4	-1.6	0.2	0.1	0.7	-1.0	-0.7
Loud music exposure frequency	0.5	0.6	2.9	-0.2	-0.7	-0.8	-0.1	-0.0	-0.4	-0.2	-1.7	0.6	1.0
Headache pain in last month	0.5	0.9	3.2	-1.8	-0.9	-0.5	-1.8	-0.7	-0.8	-0.6	-0.1	-0.1	0.1
Glaucoma (self-reported)	0.5	0.6	1.3	-0.5	0.8	0.7	0.9	0.2	1.0	0.9	0.1	-1.2	0.5
Shortness of breath walking on level ground	0.5	0.5	1.0	0.8	0.7	0.6	0.7	0.3	1.0	1.0	-0.5	-0.6	0.9
Migraine (self-reported)	0.5	0.7	1.3	-0.5	-0.8	-0.7	-1.1	0.9	-0.9	-0.8	-0.7	0.3	1.0
Age at last live birth	0.5	0.8	2.5	1.0	-0.0	0.3	0.3	1.5	-0.1	-0.1	-0.6	1.6	1.1
Leg pain on walking	0.5	0.7	1.4	-0.9	-0.6	-0.7	0.9	-0.2	-0.8	-0.8	1.0	-1.2	-0.6
Hypertension (Self-reported)	0.5	1.5	8.9	-3.0	-0.5	-0.6	-1.8	0.2	-0.7	-0.6	1.1	0.5	-0.5
Smoking status: Previous	0.5	0.7	3.7	0.3	0.7	0.5	1.9	0.2	0.2	0.2	-1.0	-0.2	1.0
Back pain experienced in last month	0.5	0.7	2.2	0.8	0.8	0.6	0.3	1.0	0.6	0.7	-0.8	1.5	0.7
Mineral and other dietary supplements	0.5	0.6	2.7	-0.4	0.9	0.6	0.2	0.5	0.8	0.6	0.4	-0.9	1.6
Medication: Gliclazide	0.5	0.5	2.1	0.4	0.4	0.6	0.1	1.4	0.2	0.1	-0.1	1.3	0.9
Illnesses of father: None of the above (group 1)	0.5	0.7	1.2	0.7	1.1	0.9	-0.8	-0.8	1.1	1.1	-0.1	-0.3	-0.5
Number of self-reported non-cancer illnesses	0.5	0.9	6.0	-0.9	-0.3	-0.3	-2.4	0.7	-0.2	0.0	0.8	-0.8	0.3
Miserableness	0.5	0.8	4.1	-0.7	-0.7	-0.9	-2.0	-0.9	-0.6	-0.5	0.4	0.6	0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.1	-1.5	0.8	0.6	-0.8	-0.2	1.1	1.1	0.3	0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	2.4	-0.3	-0.3	-0.2	1.6	-1.0	-0.8	-0.8	0.8	-0.5	-0.8
Age at First Birth	0.4	0.6	1.5	-0.9	-0.9	-0.6	-0.1	0.8	-0.5	-0.5	0.6	-0.9	-1.2
Mean Putamen Volume	0.4	0.4	1.5	-0.3	-0.7	-1.0	-0.5	0.0	-0.6	-0.6	0.1	0.3	-1.2
LDL Cholesterol	0.4	0.7	2.1	0.1	-0.5	-0.5	1.2	-0.7	-0.9	-0.9	-0.7	1.4	-0.4
Triglycerides	0.4	0.6	2.5	0.7	-0.2	-0.2	-0.7	-0.7	-0.2	-0.1	1.6	-1.0	-1.0
BMI	0.4	2.5	7.5	-0.4	1.8	0.7	-2.7	1.2	2.5	2.5	0.2	-0.3	0.1
Allergy or Eczema	0.4	1.2	3.8	0.8	0.9	1.0	1.3	1.0	0.7	0.7	-0.9	-1.0	1.9
Cardiovascular Disease	0.4	1.4	7.2	-2.7	0.3	0.4	-1.7	-0.1	-0.2	0.0	1.7	-0.4	-0.4
Lung FEV1/FVC ratio	0.4	2.0	8.3	0.1	1.6	2.0	-2.9	-0.9	1.2	1.3	0.5	-0.1	-0.9
Ever had hysterectomy (womb removed)	0.4	0.5	1.4	0.8	-0.3	-0.3	-1.2	0.8	-0.6	-0.5	0.4	-1.0	0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.8	0.6	0.4	0.6	0.4	-0.3	0.3	0.2	1.7	-0.2	-0.8
Vitamin and mineral supplements	0.4	0.5	2.8	-1.7	0.1	-0.1	1.0	0.3	0.0	0.0	0.8	0.2	0.7
Medication: Co-codamol	0.4	0.5	1.1	-0.9	-1.1	-1.0	-0.7	0.1	-0.6	-0.6	0.5	0.2	-0.4
Pack years adult smoking proportion	0.4	0.7	3.7	-1.2	0.1	0.2	-1.1	0.1	0.1	0.2	1.9	-0.2	-0.5
Townsend deprivation index at recruitment	0.4	0.6	3.3	-0.3	-0.5	-1.3	1.8	-0.5	0.1	-0.0	-0.3	0.4	0.5
Multivitamins +/- minerals	0.4	0.5	2.0	1.2	-0.4	-0.3	-0.9	0.1	-0.2	-0.0	-1.4	-0.4	-0.4
Hearing difficulty/problems with background noise	0.4	0.6	2.8	-0.1	0.1	0.2	0.2	-1.5	-0.0	-0.0	0.5	-0.7	-1.7
Allergy	0.4	0.8	4.7	-0.8	-0.1	-0.5	-2.2	-0.6	0.3	0.2	-0.0	1.3	-0.8
Time employed in main current job	0.4	0.4	1.7	-0.9	-0.0	-0.6	-1.3	0.0	0.2	0.2	0.4	0.7	-0.8
Worrier / anxious feelings	0.4	0.8	5.0	1.1	0.2	-0.0	0.7	-1.0	-0.2	-0.1	-0.1	-0.2	2.2
Hair/balding pattern: Pattern 3	0.4	0.5	2.2	-0.6	0.1	0.5	0.9	1.5	0.3	0.3	-0.8	-0.9	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.7	0.7	0.3	0.4	-0.7	-0.1	0.0	0.0	-0.7	0.1	1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.8	1.0	0.2	0.4	-0.7	-1.1	-0.2	-0.3	-0.2	-1.3	-0.1
Age at first live birth	0.4	0.7	1.5	0.6	0.7	0.8	1.0	1.2	0.4	0.4	-0.8	1.1	1.0
Pulse wave peak to peak time	0.4	0.5	1.3	0.0	-0.1	-1.1	-1.1	0.4	0.4	0.6	-0.4	1.1	0.4
Alcohol intake frequency.	0.4	0.8	3.9	-0.3	-0.2	0.0	-2.0	0.5	0.0	0.3	1.0	-0.6	1.6
Suffer from ‘nerves’	0.4	0.6	3.8	-0.1	-0.1	0.0	-0.4	-0.9	-0.2	-0.1	-0.1	0.9	2.0
Medication: Lisinopril	0.4	0.6	4.3	-0.8	0.0	-0.2	-2.1	0.2	-0.0	0.1	0.3	-0.0	0.8
Irritability	0.4	0.7	2.2	-0.0	0.7	0.4	-0.7	-0.4	0.5	0.6	-1.1	1.2	1.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.6	1.2	-0.1	-0.1	-0.2	1.3	0.3	0.3	-0.0	1.1	0.7
Pack years of smoking	0.4	0.6	3.1	-0.8	0.5	0.7	-1.0	0.3	0.4	0.5	1.8	-0.4	-0.1
Neuroticism (Nagel 2018)	0.3	0.6	2.5	1.3	0.2	0.4	-0.9	-0.5	0.0	0.4	-0.4	0.6	1.6
HDL Cholesterol	0.3	0.4	2.3	-1.5	-0.1	0.3	0.3	-0.7	-0.1	-0.2	-0.4	0.9	-0.4
Lung FVC	0.3	1.5	5.1	-0.2	0.7	-0.2	2.2	1.3	0.9	0.7	-1.9	0.8	1.6
Hair Pigment	0.3	7.2	15.0	-3.2	-3.4	-2.8	2.6	-1.8	-3.9	-3.8	0.2	0.4	-1.5
Tanning	0.3	3.7	5.9	-0.1	-2.0	-1.8	-2.4	-2.0	-1.7	-1.6	2.1	-2.4	-2.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	-0.1	-0.0	0.2	-1.2	1.2	0.2	0.2	-0.2	0.7	-0.1
Supplements: Zinc	0.3	0.3	1.0	1.0	0.3	0.4	-0.4	-0.6	0.7	0.8	-0.1	0.5	-0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.0	-0.0	-0.7	-0.6	-0.4	-0.8	-0.4	-0.3	0.1	-1.0	-0.7
Waist circumference	0.3	1.1	5.7	-0.6	0.4	0.0	-2.4	0.3	0.8	0.9	0.6	-1.6	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.7	0.7	-0.6	-0.9	-0.4	0.1	-0.5	-0.6	-0.9	1.3	0.8
Happiness	0.3	0.3	1.2	-0.3	0.1	-0.8	1.0	-0.7	0.1	0.0	0.2	1.1	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.8	-0.1	-0.4	-0.2	-0.7	0.8	-0.7	-0.9	-0.1	0.8	0.2
Tense / ‘highly strung’	0.3	0.4	1.7	-0.1	-0.2	-0.4	1.3	-1.0	-0.4	-0.4	0.2	0.0	1.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.2	1.1	0.1	-0.0	0.8	-0.9	0.7	0.6	-0.8	0.8	-1.0
Exposure to tobacco smoke outside home	0.3	0.4	1.9	-0.6	-0.2	-0.7	-0.1	-0.9	-0.2	-0.3	1.4	0.5	-0.2
Health satisfaction	0.3	0.4	2.1	0.3	0.1	-0.4	1.4	0.6	0.5	0.4	-0.4	-0.2	0.9
Eye problems/disorders: None of the above	0.3	0.4	1.0	0.6	-0.7	-0.6	-0.1	-0.5	-1.0	-0.8	-0.5	0.1	-0.3
Emphysema/chronic bronchitis	0.3	0.3	0.6	-0.0	-0.7	-0.7	-0.2	-0.2	-0.8	-0.8	0.5	-0.6	-0.6
Long-standing illness, disability or infirmity	0.3	0.5	1.2	-0.4	0.8	0.6	-0.0	1.0	1.0	1.1	0.2	-0.3	0.7
Diabetes diagnosed by doctor	0.3	0.5	1.9	0.2	-0.1	0.3	-0.4	-0.6	-0.5	-0.5	1.1	0.6	-1.4
Eye problems/disorders: Cataract	0.3	0.3	1.6	-0.3	-0.7	-0.7	0.2	1.3	-0.3	-0.4	-0.2	-0.2	-0.1
Eye problems/disorders: Glaucoma	0.3	0.4	2.4	-1.5	0.3	0.1	-0.0	-0.7	0.4	0.4	0.4	-0.8	0.1
Medication: Bendroflumethiazide	0.3	0.5	1.7	-0.6	-0.2	-0.7	-0.5	0.7	-0.3	-0.2	-0.5	1.3	0.9
Medication: Atorvastatin	0.3	0.4	1.7	0.3	0.4	0.3	-0.1	-0.2	0.5	0.5	-1.1	0.2	1.3
Number of operations (self-reported)	0.3	0.5	1.6	-1.3	-0.4	-0.7	-0.3	-0.6	-0.5	-0.4	-0.6	0.7	-0.7
Fractured/broken bones in last 5 years	0.3	0.4	0.8	0.9	0.7	0.7	0.6	0.9	0.7	0.7	-0.3	0.1	0.2
Ever depressed for a whole week	0.3	0.3	1.3	0.9	0.4	0.6	-0.6	-0.4	0.0	0.0	1.2	-0.0	0.3
Systolic Blood Pressure	0.2	1.1	5.5	-2.4	-0.5	-0.2	-1.1	-0.6	-0.7	-0.8	0.2	0.0	-1.4
Smoking Status	0.2	0.4	1.0	0.5	-0.6	-1.0	0.5	-1.0	-0.6	-0.6	-0.5	-0.5	0.1
Respiratory disease	0.2	0.4	2.0	1.0	-0.1	0.2	-0.3	-0.4	0.1	0.2	0.5	-1.4	0.4
Average weekly spirits intake	0.2	0.2	0.6	-0.7	-0.2	-0.0	-0.6	-0.4	-0.3	-0.3	0.7	0.1	-0.7
Angina	0.2	0.2	0.8	0.1	0.2	0.8	-0.9	-0.1	0.2	0.2	0.5	-0.4	0.0
Medication: Metformin	0.2	0.3	1.9	1.4	0.3	0.7	-0.1	-0.1	-0.1	-0.1	0.1	0.8	0.1
Severe depression (siblings)	0.2	0.2	0.7	-0.2	-0.4	-0.1	-0.5	0.6	-0.5	-0.4	0.2	-0.4	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.0	-0.1	-0.7	-0.7	0.1	-1.0	-0.5	-0.5	0.0	-0.3	0.7
Taking other prescription medications	0.2	0.4	1.8	-0.4	-0.7	-0.6	-1.3	0.4	-0.3	-0.2	-0.5	-0.1	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	3.1	0.5	0.3	0.6	1.8	0.4	0.1	0.1	-0.2	-0.8	0.9
Past tobacco smoking	0.2	0.3	1.7	-0.2	-0.1	-0.1	-1.3	0.0	0.4	0.5	0.8	0.7	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.3	-0.3	-0.3	-0.2	-0.3	-1.1	-0.4	-0.3	0.7	0.3	0.1
Diabetes (self-reported)	0.2	0.3	0.8	0.9	0.6	0.7	0.8	0.6	0.2	0.1	0.4	0.7	-0.3
Asthma	0.2	0.4	1.7	1.3	0.0	0.5	-0.4	0.3	0.3	0.4	0.3	-0.3	1.0
Breastfed as a baby	0.2	0.3	1.4	-0.7	-0.3	-0.4	-0.1	-0.4	-0.2	-0.1	-1.2	0.3	-0.0
Hair/balding pattern: Pattern 4	0.2	0.4	1.1	0.7	0.9	0.5	1.0	0.0	0.7	0.6	0.7	0.1	-0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	0.7	-0.2	-0.0	0.4	-1.0	-0.2	-0.2	-0.8	0.5	0.2
Number of children fathered	0.2	0.2	1.3	0.7	-0.2	-0.3	-1.1	0.2	-0.2	-0.2	0.6	-0.4	0.0
Neck or shoulder pain in last month	0.2	0.2	0.7	0.3	0.3	0.2	-0.6	0.1	0.7	0.8	0.2	0.3	-0.6
Number of full sisters	0.2	0.2	1.1	0.4	-0.2	0.1	0.6	0.4	-0.2	-0.1	0.4	-1.1	0.4
Average weekly red wine intake	0.2	0.3	1.4	0.3	-0.5	-0.2	0.6	1.2	-0.4	-0.5	-0.0	-0.5	-0.4
Asthma (self-reported)	0.2	0.4	1.2	1.1	0.1	0.7	-0.7	-0.2	0.3	0.5	0.6	-0.2	0.8
Osteoporosis (self-reported)	0.2	0.2	0.8	-0.9	0.2	0.4	0.0	-0.3	-0.1	-0.1	0.3	-0.7	-0.8
Ever taken oral contraceptive pill	0.2	0.2	1.0	-0.3	0.3	0.6	0.0	0.3	0.2	0.1	-1.0	-0.2	0.4
Illnesses of father: High blood pressure	0.2	0.3	0.7	-0.8	-0.3	-0.7	0.7	-0.6	-0.0	-0.1	0.3	-0.5	-0.8
Unable to work because of sickness or disability	0.2	0.3	0.9	0.9	0.2	0.5	-0.6	0.2	-0.1	-0.0	0.9	-0.2	0.7
Worry (Nagel 2018)	0.1	0.3	1.5	0.2	0.2	0.1	-0.4	-1.1	-0.2	0.1	0.4	-0.0	1.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	0.3	-0.4	0.2	-0.6	0.3	-0.3	-0.2	-0.4	0.5	0.3
Blood Eosinophil Count	0.1	0.8	4.0	0.4	-0.2	-0.7	-2.0	-0.7	0.4	0.5	1.0	-1.2	-0.4
Blood Platelet Count	0.1	1.6	4.7	1.0	-0.2	-0.5	-1.4	-1.9	0.5	0.4	1.5	-1.5	-2.2
Blood Red Count	0.1	1.2	4.9	-1.7	-0.7	-0.4	-0.3	1.2	-0.7	-0.8	0.2	-0.6	2.2
Relative age of first facial hair	0.1	0.3	0.7	-0.3	0.3	0.5	0.9	-0.3	0.7	0.6	-0.4	-0.2	0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.8	0.2	0.3	0.2	-0.9	-0.7	0.2	0.2	0.0	0.4	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.3	-0.5	0.6	0.4	-0.4	0.5	0.5	0.4	-0.3	0.6	0.2
Falls in the last year	0.1	0.2	0.7	0.0	0.1	-0.3	0.3	0.5	0.3	0.3	-0.7	-0.1	0.8
Wheeze or whistling in the chest in last year	0.1	0.1	0.6	0.6	-0.2	-0.1	-0.2	-0.8	0.1	0.1	0.0	-0.0	0.0
Angina (self-reported)	0.1	0.2	0.9	0.2	0.2	0.9	-0.7	0.1	0.2	0.3	0.2	-0.2	0.2
Pulse rate, automated reading	0.1	0.4	1.0	-0.2	-0.7	-0.6	-0.6	1.0	-0.8	-0.9	0.1	-0.1	0.3
Ever smoked	0.1	0.2	0.8	0.0	0.1	0.1	0.2	-0.7	-0.2	-0.4	0.2	-0.9	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.2	0.4	0.2	0.3	0.5	-0.4	0.1	0.1	0.5	-0.1	-0.1

Hub : Genes

MGAT3

Models

Trait associations