TWAS
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Usage
Models
Genes
Traits
Hub
:
Genes
TAB1
Models
#
panel
tissue
h2
h2 se
h2 P
eQTL R2
BLUP R2
ENET R2
BSLMM R2
LASSO R2
eQTL P
BLUP P
ENET P
BSLMM P
LASSO P
1
GTEx
Nerve Tibial
0.151
0.0442
1.2e-06
0.127
NA
0.124
NA
0.149
2.7e-09
NA
4.6e-09
NA
1e-10
Trait associations
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Trait
Avg chi2 ratio
Avg chi2
Max chi2
1
Fluid intelligence score
13.1
27.3
27.3
-5.2
Intelligence (Savage-Jansen 2018)
12.8
39.3
39.3
-6.3
Verbal and Numeric Reasoning (VNR)
10.9
26.2
26.2
-5.1
Chest pain or discomfort
7.8
11.2
11.2
-3.3
Medication for pain relief, constipation, heartburn
7.3
12.5
12.5
-3.5
Crohns Disease (2012)
6.7
10.8
10.8
-3.3
Irritable Bowel Disease (IBD)
6.3
15.1
15.1
-3.9
Noisy workplace
6.1
7.5
7.5
2.7
Qualifications: College or University degree
5.6
17.6
17.6
-4.2
Crohns Disease (2017)
5.3
11.6
11.6
-3.4
Medication for hormone replacement therapy
5.3
6.0
6.0
2.4
Financial difficulties in last 2 years
5.2
7.0
7.0
2.6
Medication: Ibuprofen (e.g. Nurofen)
5.2
6.6
6.6
2.6
Medication: Paracetamol
5.1
8.4
8.4
2.9
Illness, injury, bereavement, stress in last 2 years
5.1
6.2
6.2
-2.5
HbA1C
4.5
5.0
5.0
2.2
Tinnitus: Yes, but not now, but have in the past
4.5
4.8
4.8
2.2
Average weekly beer plus cider intake
4.3
6.2
6.2
2.5
Arm predicted mass (left)
4.1
20.9
20.9
-4.6
Medication for cholesterol
4.0
6.1
6.1
-2.5
Arm fat-free mass (left)
4.0
20.5
20.5
-4.5
Ulcerative Colitis
3.8
5.5
5.5
-2.3
Trunk predicted mass
3.8
21.6
21.6
-4.6
Trunk fat-free mass
3.7
21.4
21.4
-4.6
Schizophrenia (2018)
3.6
7.5
7.5
2.7
Ulcerative Colitis (UC)
3.6
6.8
6.8
-2.6
Loneliness, isolation
3.6
4.9
4.9
2.2
Ever had stillbirth, spontaneous miscarriage or termination
3.6
3.9
3.9
2.0
Heart disease (siblings)
3.6
4.4
4.4
2.1
Waist Hip Ratio (WHR)
3.4
15.4
15.4
3.9
Number of treatments/medications taken
3.4
6.0
6.0
2.5
Medication: Ibuprofen
3.4
4.1
4.1
2.0
Rheumatoid Arthritis
3.3
4.6
4.6
2.1
Medication: Lansoprazole
3.3
3.7
3.7
1.9
Arm predicted mass (right)
3.3
16.7
16.7
-4.1
Whole body fat-free mass
3.3
19.1
19.1
-4.4
Whole body water mass
3.3
19.1
19.1
-4.4
Basal metabolic rate
3.3
18.2
18.2
-4.3
Arm fat-free mass (right)
3.2
16.5
16.5
-4.1
Hand grip strength (left)
3.1
8.1
8.1
-2.8
Frequency of depressed mood in last 2 weeks
3.1
4.3
4.3
2.1
Commuting to job workplace: Walk
3.1
3.4
3.4
-1.8
Leg predicted mass (right)
3.1
16.4
16.4
-4.1
Alzheimer’s Disease (in father)
3.0
3.3
3.3
1.8
Neuroticism (2016)
3.0
4.3
4.3
2.1
Prospective memory result
3.0
3.7
3.7
1.9
Worry too long after embarrassment
3.0
5.1
5.1
-2.3
Leg fat-free mass (right)
3.0
16.0
16.0
-4.0
Schizophrenia (2014)
2.9
6.5
6.5
2.5
Leg fat-free mass (left)
2.9
15.2
15.2
-3.9
Leg predicted mass (left)
2.9
15.5
15.5
-3.9
Friendships satisfaction
2.8
3.5
3.5
-1.9
Smoking status: Current
2.7
4.2
4.2
2.1
Height
2.6
49.6
49.6
-7.0
Hand grip strength (right)
2.6
7.0
7.0
-2.7
Qualifications: None of the above
2.6
5.7
5.7
2.4
Gout (self-reported)
2.6
3.6
3.6
1.9
Bipolar Disorder or Schizophrenia
2.4
5.9
5.9
2.4
Blood White Count
2.4
17.6
17.6
4.2
Pain all over the body in last month
2.4
2.6
2.6
1.6
Qualifications: A levels/AS levels or equivalent
2.4
5.3
5.3
-2.3
Illnesses of siblings: Diabetes
2.4
2.9
2.9
-1.7
Number of incorrect matches in round
2.3
3.8
3.8
2.0
Birth weight of first child
2.3
4.2
4.2
-2.0
Peak expiratory flow (PEF)
2.3
5.4
5.4
-2.3
Mouth/teeth dental problems: Mouth ulcers
2.3
3.7
3.7
-1.9
Chronic bronchitis/emphysema (mother)
2.2
2.6
2.6
-1.6
Medication: Aspirin
2.2
2.8
2.8
1.7
Financial situation satisfaction
2.2
2.7
2.7
1.6
Medication: Paracetamol
2.2
3.4
3.4
1.8
Commuting to job workplace: Cycle
2.2
2.7
2.7
-1.6
Relative age voice broke
2.1
3.1
3.1
-1.8
Pulse wave Arterial Stiffness index
2.1
2.4
2.4
-1.6
High blood pressure (mother)
2.0
2.8
2.8
1.7
Had menopause
2.0
2.6
2.6
-1.6
Forced expiratory volume in 1-second (FEV1)
2.0
6.9
6.9
-2.6
Breast cancer (self-reported)
2.0
2.4
2.4
-1.5
Type 2 Diabetes (T2D) (2012)
1.9
2.2
2.2
-1.5
Fed-up feelings
1.9
3.5
3.5
1.9
Hip circumference
1.9
8.2
8.2
-2.9
Birth weight
1.9
4.0
4.0
-2.0
Overall health rating
1.9
4.1
4.1
2.0
Medication: Aspirin
1.9
2.5
2.5
1.6
Weight
1.8
8.8
8.8
-3.0
Standing height
1.8
18.3
18.3
-4.3
Diabetes (mother)
1.7
2.2
2.2
1.5
Frequency of tiredness / lethargy in last 2 weeks
1.7
2.7
2.7
1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria
1.7
2.0
2.0
1.4
Wears glasses or contact lenses
1.7
2.0
2.0
-1.4
Hearing aid user
1.7
2.0
2.0
-1.4
Chronotype (morning person)
1.6
3.6
3.6
-1.9
Impedance of arm (right)
1.6
7.5
7.5
2.7
Average weekly champagne plus white wine intake
1.6
2.1
2.1
-1.5
Heel T-Score
1.5
11.9
11.9
3.5
Current tobacco smoking
1.5
2.5
2.5
1.6
Age when periods started (menarche)
1.5
3.7
3.7
1.9
Had other major operations
1.5
1.8
1.8
1.3
Hayfever/allergic rhinitis (self-reported)
1.5
1.9
1.9
-1.4
Pulse rate
1.5
2.5
2.5
1.6
Exposure to tobacco smoke at home
1.5
1.6
1.6
-1.3
Age started oral contraceptive pill
1.5
1.9
1.9
-1.4
Depression (Nagel 2018)
1.4
2.2
2.2
1.5
Mean Putamen Volume
1.4
1.6
1.6
1.3
Heel bone mineral density (BMD) T-score, automated (left)
1.4
3.1
3.1
1.8
Forced expiratory volume in 1-second (FEV1), Best measure
1.4
4.6
4.6
-2.1
Medication: Ventolin 100micrograms inhaler
1.4
1.7
1.7
-1.3
Medication: Allopurinol
1.4
1.8
1.8
1.4
Ovarian Cancer
1.3
1.7
1.7
-1.3
Lung cancer (father)
1.3
1.5
1.5
-1.2
Impedance of arm (left)
1.3
6.2
6.2
2.5
Qualifications: O levels/GCSEs or equivalent
1.3
2.1
2.1
-1.4
Impedance of whole body
1.3
6.7
6.7
2.6
Bipolar Disorder (2011)
1.2
1.2
1.2
1.1
Impedance of leg (right)
1.2
5.8
5.8
2.4
Sitting height
1.2
8.6
8.6
-2.9
Impedance of leg (left)
1.2
5.6
5.6
2.4
Father’s age at death
1.2
1.6
1.6
-1.3
Medication: Cholesterol lowering
1.2
1.8
1.8
-1.3
Comparative height size at age 10
1.2
6.4
6.4
-2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)
1.2
1.4
1.4
1.2
Ever had bowel cancer screening
1.2
1.4
1.4
-1.2
Osteoarthritis (self-reported)
1.2
1.5
1.5
1.2
Mother’s age at death
1.2
1.5
1.5
-1.2
Cholesterol lowering medication
1.2
1.7
1.7
1.3
Alzheimer’s Disease (in mother)
1.1
1.3
1.3
-1.1
Breast Cancer
1.1
2.6
2.6
1.6
Stomach or abdominal pain in last month
1.1
1.3
1.3
-1.2
Illnesses of mother
1.1
1.4
1.4
-1.2
Forced vital capacity (FVC), Best measure
1.1
3.9
3.9
-2.0
Number of full brothers
1.1
1.3
1.3
-1.2
Angina (self-reported)
1.1
1.4
1.4
-1.2
Supplements: Fish oil (including cod liver oil)
1.1
1.4
1.4
1.2
Diastolic blood pressure, automated reading
1.1
3.5
3.5
-1.9
Forced vital capacity (FVC)
1.0
3.8
3.8
-1.9
Mouth/teeth dental problems: Loose teeth
1.0
1.2
1.2
1.1
Coronary Artery Disease (CAD)
0.9
1.0
1.0
1.0
Lung FEV1/FVC ratio
0.9
4.7
4.7
-2.2
Angina
0.9
1.2
1.2
-1.1
Medication: Co-codamol
0.9
1.0
1.0
1.0
Townsend deprivation index at recruitment
0.9
1.3
1.3
1.1
Nervous feelings
0.9
1.8
1.8
1.3
Diabetes (self-reported)
0.9
1.4
1.4
-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression
0.9
1.3
1.3
-1.2
Pulse wave reflection index
0.9
1.2
1.2
-1.1
Pulse wave peak to peak time
0.9
1.1
1.1
1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)
0.9
1.0
1.0
1.0
Tinnitus: Yes, now most or all of the time
0.9
1.1
1.1
1.0
Comparative body size at age 10
0.8
2.2
2.2
-1.5
Qualifications: NVQ or HND or HNC or equivalent
0.8
0.9
0.9
1.0
Depressed Affect (Nagel 2018)
0.7
1.6
1.6
1.2
Maternal smoking around birth
0.7
1.1
1.1
1.0
Frequency of tenseness / restlessness in last 2 weeks
0.7
1.1
1.1
1.0
Arm fat mass (right)
0.7
2.9
2.9
-1.7
Forced expiratory volume in 1-second (FEV1), predicted
0.7
1.5
1.5
-1.2
Eye problems/disorders: Cataract
0.7
0.8
0.8
0.9
Osteoporosis (self-reported)
0.7
0.9
0.9
-1.0
Average weekly fortified wine intake
0.6
0.7
0.7
-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks
0.6
0.7
0.7
0.9
Medication: Ramipril
0.6
0.8
0.8
0.9
Alcohol intake versus 10 years previously
0.6
0.9
0.9
0.9
Length of working week for main job
0.6
0.7
0.7
-0.8
Mood swings
0.6
1.0
1.0
1.0
Arm fat mass (left)
0.6
2.5
2.5
-1.6
Miserableness
0.6
1.0
1.0
1.0
Leg fat mass (left)
0.6
2.2
2.2
-1.5
Major Depression (MDD)
0.5
0.7
0.7
0.8
Medication: Metformin
0.5
0.8
0.8
-0.9
Supplements: Glucosamine
0.5
0.6
0.6
0.8
Heel bone mineral density (BMD) T-score, automated (right)
0.5
1.2
1.2
1.1
Happiness
0.5
0.6
0.6
0.8
Hypothyroidism/myxoedema (self-reported)
0.5
0.9
0.9
0.9
Medication: Blood pressure
0.5
0.9
0.9
1.0
Leg fat mass (right)
0.5
1.8
1.8
-1.3
Medication: Gliclazide
0.5
0.5
0.5
-0.7
Ever had prostate specific antigen (PSA) test
0.5
0.6
0.6
0.8
Reaction Time
0.4
0.8
0.8
0.9
Age at First Birth
0.4
0.6
0.6
0.8
Smoking Status
0.4
1.0
1.0
1.0
Eye problems/disorders: Diabetes related eye disease
0.4
0.4
0.4
-0.7
Taking other prescription medications
0.4
0.6
0.6
0.8
Mouth/teeth dental problems
0.4
0.6
0.6
0.8
Time employed in main current job
0.4
0.4
0.4
0.7
Mouth/teeth dental problems: Dentures
0.4
0.7
0.7
-0.9
Headache pain in last month
0.4
0.7
0.7
0.9
Exposure to tobacco smoke outside home
0.4
0.5
0.5
0.7
Age at first live birth
0.4
0.7
0.7
-0.8
Eye problems/disorders: None of the above
0.4
0.4
0.4
0.7
Migraine (self-reported)
0.4
0.5
0.5
0.7
Whole body fat mass
0.4
1.5
1.5
-1.2
Family relationship satisfaction
0.4
0.4
0.4
0.7
Knee pain experienced in last month
0.4
0.6
0.6
0.8
Illnesses of father: None of the above (group 1)
0.4
0.5
0.5
-0.7
Fractured/broken bones in last 5 years
0.4
0.5
0.5
-0.7
Alcohol drinker status: Previous
0.4
0.4
0.4
-0.6
Fasting Glucose
0.3
0.3
0.3
-0.6
Lupus
0.3
0.4
0.4
0.6
Allergy or Eczema
0.3
0.9
0.9
-0.9
Tanning
0.3
3.6
3.6
1.9
Serious illness, injury or assault to yourself
0.3
0.4
0.4
0.6
Diverticular disease/diverticulitis (self-reported)
0.3
0.4
0.4
0.6
Medication: Atenolol
0.3
0.4
0.4
0.6
Chronic bronchitis/emphysema (father)
0.3
0.4
0.4
0.6
Body mass index (BMI)
0.3
1.2
1.2
-1.1
Trunk fat mass
0.3
1.4
1.4
-1.2
Loud music exposure frequency
0.3
0.3
0.3
0.6
Emphysema/chronic bronchitis
0.3
0.4
0.4
0.6
Smoking status: Previous
0.3
0.4
0.4
-0.6
Long-standing illness, disability or infirmity
0.3
0.4
0.4
-0.7
Mineral and other dietary supplements
0.3
0.4
0.4
-0.6
Commuting to job workplace: Public transport
0.3
0.3
0.3
-0.6
Pain type(s) experienced in last month: Hip pain
0.3
0.4
0.4
-0.7
Alcohol drinker status: Never
0.3
0.4
0.4
-0.6
Number of operations (self-reported)
0.3
0.4
0.4
0.6
Ever depressed for a whole week
0.3
0.4
0.4
-0.6
Unable to work because of sickness or disability
0.3
0.4
0.4
-0.6
Schizophrenia vs Biploar Disorder
0.2
0.3
0.3
0.6
Body Mass Index (BMI) (2010)
0.2
0.3
0.3
-0.5
Type 2 Diabetes (T2D) (2018)
0.2
0.3
0.3
-0.6
Hair Pigment
0.2
5.2
5.2
2.3
Sensitivity / hurt feelings
0.2
0.3
0.3
0.6
Systolic blood pressure, automated reading
0.2
0.6
0.6
-0.8
Supplements: Zinc
0.2
0.2
0.2
-0.4
Medication: Levothyroxine sodium
0.2
0.4
0.4
-0.6
Hair/balding pattern: Pattern 4
0.2
0.4
0.4
-0.7
Ever highly irritable/argumentative for 2 days
0.2
0.2
0.2
-0.4
Glaucoma (self-reported)
0.2
0.2
0.2
-0.4
Reason for reducing amount of alcohol drunk: Health precaution
0.2
0.2
0.2
-0.4
Health satisfaction
0.2
0.3
0.3
0.5
Shortness of breath walking on level ground
0.2
0.3
0.3
-0.5
Heart disease (mother)
0.2
0.2
0.2
-0.5
Leg pain on walking
0.2
0.2
0.2
0.5
Commuting to job workplace: Car/motor vehicle
0.2
0.2
0.2
0.4
Diabetes diagnosed by doctor
0.2
0.3
0.3
-0.6
Back pain experienced in last month
0.2
0.2
0.2
-0.5
Asthma (self-reported)
0.2
0.4
0.4
-0.6
Medication: Blood pressure
0.2
0.4
0.4
0.6
Illnesses of father: High blood pressure
0.2
0.3
0.3
0.5
Irritability
0.2
0.3
0.3
-0.6
Pain experienced in last month
0.2
0.4
0.4
-0.6
Heart attack/myocardial infarction (self-reported)
0.2
0.2
0.2
-0.5
Pack years of smoking
0.2
0.2
0.2
-0.5
Bipolar Disorder (2018)
0.1
0.2
0.2
0.5
Alzheimer’s Disease (including proxy)
0.1
0.1
0.1
0.3
Prostate Cancer
0.1
0.1
0.1
0.3
HDL Cholesterol
0.1
0.2
0.2
-0.4
LDL Cholesterol
0.1
0.1
0.1
0.3
Blood Eosinophil Count
0.1
0.7
0.7
0.8
BMI
0.1
0.3
0.3
-0.6
Cardiovascular Disease
0.1
0.3
0.3
-0.6
Hypothyroidism (self reported)
0.1
0.2
0.2
0.5
Hearing difficulty/problems: Yes
0.1
0.2
0.2
-0.4
Relative age of first facial hair
0.1
0.1
0.1
-0.3
Ever used hormone-replacement therapy (HRT)
0.1
0.2
0.2
-0.4
Bilateral oophorectomy (both ovaries removed)
0.1
0.1
0.1
0.4
Hayfever, allergic rhinitis or eczema
0.1
0.3
0.3
-0.5
Multivitamins +/- minerals
0.1
0.1
0.1
0.3
Hearing difficulty/problems with background noise
0.1
0.1
0.1
-0.3
Hair/balding pattern: Pattern 2
0.1
0.1
0.1
0.3
Ever unenthusiastic/disinterested for a whole week
0.1
0.2
0.2
0.4
Heart attack
0.1
0.1
0.1
-0.3
Allergy
0.1
0.3
0.3
0.5
Medication: Simvastatin
0.1
0.1
0.1
-0.3
Neuroticism score
0.1
0.3
0.3
0.5
Falls in the last year
0.1
0.1
0.1
0.3
Hair/balding pattern: Pattern 3
0.1
0.1
0.1
-0.4
Asthma
0.1
0.2
0.2
-0.5
Breastfed as a baby
0.1
0.2
0.2
0.4
Tense / ‘highly strung’
0.1
0.1
0.1
0.3
Blood clot in the leg (DVT)
0.1
0.1
0.1
0.3
Leg fat percentage (right)
0.1
0.2
0.2
-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression
0.1
0.1
0.1
-0.4
Number of children fathered
0.1
0.1
0.1
0.3
Neck or shoulder pain in last month
0.1
0.1
0.1
0.3
Mean time to correctly identify matches
0.1
0.2
0.2
0.4
Pulse rate, automated reading
0.1
0.3
0.3
0.6
Illnesses of father: Heart disease
0.1
0.1
0.1
-0.3
Handedness (chirality/laterality): Left-handed
0.1
0.1
0.1
-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage
0.1
0.1
0.1
-0.4
Number of self-reported non-cancer illnesses
0.1
0.2
0.2
0.4
Guilty feelings
0.1
0.1
0.1
-0.4
Ever taken oral contraceptive pill
0.1
0.2
0.2
-0.4
Medication: Bendroflumethiazide
0.1
0.2
0.2
0.4
Medication: Lisinopril
0.1
0.1
0.1
0.3
Leg fat percentage (left)
0.1
0.3
0.3
-0.5
Myopia
0.1
0.1
0.1
0.3
Vascular/heart problems diagnosed by doctor
0.1
0.2
0.2
0.4
Supplements: Calcium
0.1
0.1
0.1
0.3
Basal cell carcinoma (self-reported)
0.1
0.1
0.1
-0.3
Neuroticism (Nagel 2018)
0.0
0.1
0.1
-0.3
Worry (Nagel 2018)
0.0
0.0
0.0
-0.1
Primary Biliary Cirrhosis
0.0
0.0
0.0
-0.1
Triglycerides
0.0
0.0
0.0
0.1
Blood Platelet Count
0.0
0.5
0.5
0.7
Blood Red Count
0.0
0.1
0.1
0.4
Systolic Blood Pressure
0.0
0.0
0.0
0.0
Respiratory disease
0.0
0.0
0.0
-0.2
Lung FVC
0.0
0.2
0.2
0.5
Neuroticism
0.0
0.0
0.0
-0.1
Average weekly spirits intake
0.0
0.0
0.0
-0.2
Other serious medical condition/disability diagnosed by doctor
0.0
0.1
0.1
-0.2
Ever had hysterectomy (womb removed)
0.0
0.0
0.0
-0.2
Vitamin and mineral supplements
0.0
0.0
0.0
0.1
Diabetes (father)
0.0
0.0
0.0
-0.2
Severe depression (siblings)
0.0
0.0
0.0
0.1
Pack years adult smoking proportion
0.0
0.0
0.0
-0.1
Trunk fat percentage
0.0
0.0
0.0
-0.2
Qualifications: CSEs or equivalent
0.0
0.0
0.0
0.2
High blood pressure
0.0
0.0
0.0
0.2
Waist circumference
0.0
0.0
0.0
0.1
Past tobacco smoking
0.0
0.0
0.0
0.1
Alcohol usually taken with meals
0.0
0.0
0.0
0.2
Illnesses of siblings
0.0
0.0
0.0
0.2
Arm fat percentage (right)
0.0
0.0
0.0
-0.2
Worrier / anxious feelings
0.0
0.0
0.0
0.0
Number of live births
0.0
0.0
0.0
-0.0
Serious illness, injury or assault of a close relative in last 2 years
0.0
0.0
0.0
0.1
Depression (self-reported)
0.0
0.0
0.0
0.1
Mouth/teeth dental problems: Bleeding gums
0.0
0.1
0.1
-0.3
Medication for cholesterol, blood pressure or diabetes
0.0
0.1
0.1
0.2
Medication: Amlodipine
0.0
0.0
0.0
0.1
High blood pressure (siblings)
0.0
0.0
0.0
-0.0
Body fat percentage
0.0
0.1
0.1
-0.2
Wheeze or whistling in the chest in last year
0.0
0.0
0.0
-0.1
Medication: Omeprazole
0.0
0.0
0.0
0.1
Medication: Seretide 50 evohaler
0.0
0.0
0.0
0.2
Alcohol intake frequency.
0.0
0.1
0.1
0.3
Number of full sisters
0.0
0.0
0.0
-0.0
Suffer from ‘nerves’
0.0
0.0
0.0
0.0
Had major operations
0.0
0.0
0.0
0.2
Age at last live birth
0.0
0.1
0.1
-0.3
Supplements: Vitamin C
0.0
0.0
0.0
-0.1
Hypertension (Self-reported)
0.0
0.1
0.1
0.3
Arm fat percentage (left)
0.0
0.0
0.0
-0.1
Average weekly red wine intake
0.0
0.1
0.1
0.3
Qualifications: nursing, teaching
0.0
0.0
0.0
-0.1
Eye problems/disorders: Glaucoma
0.0
0.0
0.0
0.1
High cholesterol (Self-reported)
0.0
0.0
0.0
0.1
Medication: Atorvastatin
0.0
0.1
0.1
-0.2
Ever smoked
0.0
0.0
0.0
-0.2
Risk taking
0.0
0.0
0.0
-0.1
Medication: Omeprazole (e.g. Zanprol)
0.0
0.1
0.1
0.2
Deep venous thrombosis (DVT) (self-reported)
0.0
0.0
0.0
-0.2