Best TWAS P=1.36e-08 · Best GWAS P=1.14e-07 conditioned to 0.125
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | AFF3 | 0.31 | 0.24 | enet | 32 | 0.25 | 9.2e-31 | 4.8 | 5.3 | 9.9e-08 | 0.32 | 0.13 | 0.86 | TRUE |
2 | GTEx | Adrenal Gland | CHST10 | 0.18 | 0.04 | lasso | 4 | 0.05 | 5.6e-03 | 4.7 | -5.7 | 1.4e-08 | -0.82 | 0.16 | 0.56 | TRUE |
3 | GTEx | Artery Tibial | AFF3 | 0.06 | 0.04 | enet | 6 | 0.04 | 4.3e-04 | -4.7 | 5.3 | 1.2e-07 | 0.41 | 0.10 | 0.86 | FALSE |