Hub : Genes

CHST10

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0520 0.0190 7.0e-05 0.023 0.040 0.035 NA 0.017 6.7e-04 0.00001 3.8e-05 NA 2.9e-03
2 GTEx Adrenal Gland 0.1824 0.0752 8.7e-04 0.040 NA 0.022 NA 0.053 1.4e-02 NA 5.3e-02 NA 5.6e-03
3 GTEx Cells EBV-transformed lymphocytes 0.2490 0.0950 2.3e-03 0.148 NA 0.079 NA 0.122 1.6e-05 NA 1.5e-03 NA 9.0e-05
4 GTEx Heart Left Ventricle 0.1746 0.0575 5.1e-05 0.012 NA 0.035 NA 0.042 6.8e-02 NA 5.8e-03 NA 2.8e-03
5 GTEx Muscle Skeletal 0.0645 0.0258 1.9e-03 0.015 NA 0.014 NA 0.015 1.2e-02 NA 1.4e-02 NA 1.2e-02
6 GTEx Testis 0.2520 0.0760 3.6e-04 0.116 NA 0.128 NA 0.186 7.8e-06 NA 2.7e-06 NA 1.1e-08
7 GTEx Thyroid 0.0530 0.0230 2.0e-03 0.050 NA 0.022 NA 0.029 1.1e-04 NA 8.2e-03 NA 2.6e-03
8 TCGA Brain Lower Grade Glioma 0.0421 0.0238 5.9e-04 0.033 0.022 0.018 NA 0.007 1.1e-04 0.00150 3.2e-03 NA 4.4e-02
9 TCGA Thyroid Carcinoma 0.0410 0.0210 5.3e-04 0.038 0.027 0.014 NA 0.034 1.1e-04 0.00100 1.6e-02 NA 2.6e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.4 0.6 1.5 -0.7 0.7 -0.7 0.7 1.2 -0.2 -0.5 -0.9 -0.7
Bipolar Disorder or Schizophrenia 0.5 1.3 2.2 -1.0 1.2 -1.5 0.6 0.9 -0.8 -1.3 -1.2 -1.3
Depressed Affect (Nagel 2018) 2.4 5.1 10.2 -2.4 2.3 -2.7 2.1 1.5 -1.1 -3.2 -1.2 -2.9
Depression (Nagel 2018) 0.6 0.9 4.1 -1.0 0.3 -1.2 -0.4 -0.4 -2.0 -0.8 -0.4 -0.4
Intelligence (Savage-Jansen 2018) 11.2 34.4 58.2 5.0 -7.6 7.2 -5.4 -2.0 0.5 7.5 6.0 6.9
Neuroticism (Nagel 2018) 0.6 1.4 4.0 -1.3 0.6 -1.0 1.4 0.7 0.4 -2.0 -0.6 -1.7
Schizophrenia (2018) 0.4 0.8 1.6 -0.7 1.0 -1.3 0.4 0.1 -0.6 -1.3 -0.8 -1.1
Schizophrenia vs Biploar Disorder 0.2 0.3 0.9 0.8 -0.3 -0.2 -0.1 -0.2 -0.9 -0.6 -0.1 -0.7
Worry (Nagel 2018) 0.6 1.2 3.1 1.5 -1.7 1.8 -0.3 0.1 1.0 0.6 0.8 0.6
Alzheimer’s Disease (in mother) 0.4 0.5 1.6 0.6 -1.3 0.0 -0.4 -0.7 -0.2 0.9 -0.9 0.4
Alzheimer’s Disease (in father) 0.8 0.9 1.8 0.5 -0.7 1.0 -0.9 -0.3 -0.8 1.4 1.4 1.1
Alzheimer’s Disease (including proxy) 0.5 0.7 1.4 1.1 -1.1 0.2 -0.8 -0.3 -0.7 1.2 0.3 0.9
Crohns Disease (2017) 0.6 1.3 2.6 1.4 -1.0 1.2 -0.8 -0.5 -0.1 1.2 1.5 1.6
Irritable Bowel Disease (IBD) 0.1 0.3 1.5 0.0 1.2 -0.3 0.7 0.2 -0.3 -0.4 0.5 -0.1
Ulcerative Colitis (UC) 1.2 2.2 6.7 -1.1 2.6 -1.4 1.6 0.4 -0.8 -1.5 -1.2 -1.7
Major Depression (MDD) 1.4 1.7 4.4 -0.8 2.1 -2.0 0.5 0.3 -1.1 -1.6 -1.2 -0.9
Reaction Time 0.2 0.3 1.3 1.2 -0.5 0.6 -0.5 0.4 -0.6 0.2 0.5 0.2
Verbal and Numeric Reasoning (VNR) 9.0 21.5 37.7 3.9 -6.1 6.0 -4.0 -1.0 1.7 5.7 4.9 5.3
Breast Cancer 0.1 0.3 2.0 -0.4 0.3 -0.3 -0.1 -1.4 -0.1 -0.3 -0.5 -0.4
Ovarian Cancer 0.5 0.6 4.5 0.4 -0.2 0.3 0.4 -0.6 2.1 -0.0 -0.1 0.5
Prostate Cancer 0.5 0.8 2.9 0.4 1.7 -0.7 1.0 0.7 0.6 -1.0 -0.6 -0.6
Age at First Birth 5.5 8.0 24.5 2.5 -5.0 3.1 -2.2 -1.4 -0.1 3.3 2.4 2.8
Bipolar Disorder (2011) 1.1 1.1 4.5 -0.7 0.6 -0.8 1.6 2.1 0.6 -0.7 0.1 -0.8
Body Mass Index (BMI) (2010) 0.4 0.6 1.3 -0.7 0.7 -1.1 0.2 0.7 -0.3 -1.0 -0.7 -0.6
Coronary Artery Disease (CAD) 0.5 0.6 1.5 0.3 0.9 -0.1 1.2 1.2 -0.3 -0.5 0.0 -1.1
Crohns Disease (2012) 0.4 0.6 1.6 1.2 -0.4 0.2 -0.8 -0.0 -0.4 0.9 0.7 1.3
Mean Putamen Volume 1.2 1.4 3.1 -1.8 1.2 -1.5 0.2 1.2 -0.6 -1.5 -0.9 -0.9
Fasting Glucose 0.7 0.9 2.2 -0.4 1.2 -1.5 0.7 0.8 0.1 -1.1 -0.8 -1.1
HbA1C 2.4 2.7 5.3 1.8 -1.6 1.2 -2.3 -1.2 -1.2 1.7 1.2 2.1
HDL Cholesterol 1.2 1.9 4.2 1.4 -2.1 1.4 -0.9 1.3 -0.1 1.8 1.2 1.3
LDL Cholesterol 0.2 0.3 0.7 -0.1 0.3 -0.5 0.8 -0.2 0.0 -0.5 -0.7 -0.8
Lupus 0.3 0.4 1.8 -0.5 0.4 0.2 -0.3 1.4 -1.2 0.1 -0.2 0.0
Neuroticism (2016) 0.4 0.5 1.8 -0.7 -0.3 -0.8 0.0 0.2 -0.9 -0.7 -1.4 -0.8
Primary Biliary Cirrhosis 0.2 0.3 1.6 -0.5 1.3 -0.7 0.0 0.8 -0.2 -0.4 -0.2 0.0
Rheumatoid Arthritis 2.0 2.7 13.5 -1.8 3.7 -0.8 0.6 -0.8 -1.4 -0.8 -1.1 -1.4
Schizophrenia (2014) 0.3 0.7 1.4 -0.5 1.0 -1.1 0.6 0.6 -0.3 -1.2 -0.6 -1.1
Triglycerides 0.6 0.9 1.7 -1.0 0.9 -0.9 0.8 -0.3 -0.4 -1.3 -1.1 -1.3
Type 2 Diabetes (T2D) (2012) 1.1 1.2 2.6 -1.3 0.7 -1.6 0.2 1.2 -0.9 -1.4 -1.1 -1.0
Ulcerative Colitis 0.7 1.0 4.4 -0.4 2.1 -1.1 0.7 -0.9 -0.4 -0.6 -0.4 -0.9
Blood Eosinophil Count 0.2 1.8 6.5 2.5 0.4 0.9 -0.8 0.8 -1.8 0.7 1.6 0.8
Blood Platelet Count 0.1 0.7 1.2 0.3 -1.0 -0.2 0.9 1.1 -0.8 -0.5 -0.8 -1.1
Blood Red Count 0.7 7.0 36.6 -1.9 6.0 -2.3 2.2 1.2 -0.9 -2.1 -0.4 -2.4
Blood White Count 0.4 2.9 5.4 -1.5 1.7 -1.7 1.7 2.3 -0.8 -1.9 -1.3 -2.0
Heel T-Score 0.6 4.8 14.7 2.2 -3.8 2.4 -1.9 1.9 -0.6 1.9 1.7 2.1
BMI 4.5 26.2 56.0 -6.0 5.8 -5.1 4.7 2.0 1.1 -7.5 -4.7 -6.0
Height 0.1 2.3 7.1 -2.1 -1.8 0.1 -1.4 -2.7 0.7 -0.2 -1.9 0.5
Waist Hip Ratio (WHR) 1.3 5.9 12.8 -3.6 3.2 -2.3 1.5 -0.0 -0.8 -2.9 -2.5 -2.8
Systolic Blood Pressure 0.4 1.8 6.6 -0.4 2.1 -0.9 1.2 2.6 -0.2 -0.8 -0.5 -1.1
Smoking Status 4.8 11.5 20.7 -4.5 3.3 -3.8 2.3 1.8 -0.9 -4.0 -4.4 -3.7
Allergy or Eczema 0.2 0.5 3.6 0.7 0.1 -0.0 0.2 -1.9 0.4 -0.5 -0.4 -0.3
Cardiovascular Disease 0.2 0.6 1.9 -0.5 0.9 -0.0 0.4 -0.0 -0.2 -1.1 -1.4 -1.1
Hypothyroidism (self reported) 2.1 4.8 12.0 -2.4 3.5 -2.3 1.7 1.6 -0.5 -3.0 -1.0 -2.2
Respiratory disease 0.4 0.9 3.2 0.6 1.8 0.1 1.0 -0.7 0.7 -0.9 -0.2 -1.2
Type 2 Diabetes (T2D) (2018) 0.6 1.0 2.4 -1.1 1.3 -1.3 0.3 0.2 -0.5 -1.6 -1.0 -1.0
Lung FEV1/FVC ratio 0.5 2.4 6.0 -2.3 2.4 -0.9 1.7 1.9 0.5 -1.2 -0.7 -1.2
Lung FVC 0.3 1.4 4.1 -2.0 1.6 0.2 0.1 -1.1 1.7 0.3 -1.2 -0.2
Neuroticism 0.1 0.3 1.1 -0.6 -0.1 -0.4 0.6 0.1 0.6 -1.0 -0.5 -0.7
Chronotype (morning person) 1.9 4.5 8.2 2.8 -2.9 1.3 -2.2 -0.9 -1.0 2.1 2.5 2.3
Hair Pigment 0.1 2.7 4.9 -1.6 1.7 -2.2 0.5 0.7 -1.0 -2.2 -2.2 -1.8
Tanning 0.1 1.4 2.1 -1.2 1.5 -1.2 1.3 -0.8 1.1 -1.0 -1.1 -1.3
Hand grip strength (left) 1.2 3.3 5.7 1.6 -2.4 2.2 -1.8 -0.4 1.1 2.1 1.4 2.3
Number of treatments/medications taken 1.3 2.3 6.6 -1.0 1.4 -1.6 0.8 -0.0 -0.9 -1.7 -2.6 -1.9
Average weekly spirits intake 0.3 0.4 1.8 -0.7 -0.6 -0.4 -0.1 1.3 -0.5 -0.6 0.1 -0.5
Sensitivity / hurt feelings 0.3 0.4 1.0 0.6 -0.8 0.4 -0.2 0.5 1.0 0.5 1.0 0.5
Frequency of depressed mood in last 2 weeks 0.5 0.6 1.7 -0.9 0.7 -1.3 -0.3 -0.8 -0.8 -0.9 -0.8 -0.3
Hearing difficulty/problems: Yes 0.1 0.2 0.6 0.0 0.2 0.0 0.6 0.7 0.3 -0.5 0.0 -0.5
Relative age of first facial hair 0.8 1.7 3.9 -2.0 1.8 -1.4 0.6 0.6 -0.5 -1.3 -1.3 -1.5
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 4.2 0.7 -2.1 1.0 -0.7 -0.8 0.4 1.2 1.2 1.3
Ever used hormone-replacement therapy (HRT) 0.2 0.3 0.9 0.0 -0.2 -0.7 -0.2 -0.0 -0.7 -0.6 -0.9 -0.4
Ever had hysterectomy (womb removed) 0.4 0.4 1.7 -0.7 0.8 -0.8 -0.3 0.0 -1.3 -0.6 -0.1 -0.3
Systolic blood pressure, automated reading 0.4 1.2 6.5 0.4 1.3 -0.2 0.8 2.6 -0.6 -0.6 0.9 -0.4
Eye problems/disorders: Diabetes related eye disease 0.2 0.3 0.6 0.1 0.3 -0.4 0.7 0.2 -0.7 -0.4 -0.4 -0.8
Angina 2.4 3.1 6.9 -1.7 2.6 -1.7 1.6 0.6 0.2 -2.2 -1.8 -2.0
Medication for hormone replacement therapy 1.2 1.4 4.2 0.4 -1.9 0.3 -2.0 -0.6 -1.3 0.8 -0.4 1.1
Vitamin and mineral supplements 0.7 0.9 1.7 -1.1 1.3 -0.7 1.0 0.9 0.1 -1.0 -0.4 -1.2
Supplements: Zinc 3.8 4.1 6.6 1.6 -2.1 2.4 -2.6 0.0 -1.0 2.2 2.4 2.5
Medication: Co-codamol 1.1 1.2 2.2 -1.0 1.5 -1.4 1.1 -1.2 1.0 -1.1 -0.5 -0.9
Medication: Metformin 0.8 1.2 3.0 -0.5 1.1 -1.5 0.2 0.4 -1.7 -1.3 -1.0 -1.0
Diabetes (father) 0.3 0.4 1.6 0.3 0.1 -0.3 0.6 0.8 -0.2 -1.3 -0.1 -0.8
Diabetes (mother) 0.4 0.5 1.9 -1.4 0.1 0.3 0.3 0.9 -0.1 -0.9 -0.4 -0.6
Severe depression (siblings) 0.2 0.2 0.6 0.1 -0.8 0.3 -0.7 0.2 -0.5 -0.3 -0.0 0.2
Pack years adult smoking proportion 0.2 0.3 0.7 0.6 0.4 -0.2 0.8 0.5 0.2 -0.6 0.6 -0.4
Impedance of leg (right) 0.1 0.5 1.5 -1.2 0.7 -0.4 0.3 1.0 -0.7 0.2 -0.6 -0.4
Leg fat-free mass (left) 0.6 3.0 9.0 -2.4 1.5 -1.7 1.0 0.3 1.0 -3.0 -1.5 -1.7
Trunk fat percentage 4.8 19.3 35.6 -5.3 4.7 -4.9 3.5 2.4 -0.2 -6.0 -4.5 -5.0
Hand grip strength (right) 1.0 2.7 5.1 1.7 -2.3 2.0 -1.7 -0.2 0.9 1.9 1.2 1.9
Townsend deprivation index at recruitment 2.3 3.3 6.7 -1.9 1.9 -2.5 0.4 -0.2 -1.5 -2.0 -2.6 -1.8
Current tobacco smoking 1.9 3.1 6.1 -1.6 2.1 -1.9 0.7 0.7 -2.5 -1.9 -2.0 -1.9
Average weekly fortified wine intake 0.2 0.2 1.1 -0.2 -0.2 0.5 -0.6 1.1 -0.6 -0.3 -0.1 -0.0
Maternal smoking around birth 1.5 2.1 10.6 -1.7 1.2 -0.6 -1.1 0.4 -3.2 -0.8 -1.3 -0.5
Fed-up feelings 4.7 8.6 15.3 -3.6 3.5 -3.8 1.7 1.1 -1.7 -3.9 -2.4 -3.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 7.3 -0.1 0.2 -0.9 -1.4 -1.3 -2.7 -0.1 -0.0 0.6
Relative age voice broke 0.6 0.9 2.7 -1.6 1.1 -0.9 0.1 -0.0 -0.1 -0.7 -1.4 -1.0
Taking other prescription medications 2.6 3.9 7.0 -2.0 2.6 -2.0 0.2 -0.3 -2.5 -2.0 -2.6 -1.9
Age when periods started (menarche) 3.3 7.8 16.1 -4.0 2.5 -2.7 2.7 3.0 0.6 -2.7 -2.7 -3.1
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.4 0.1 0.2 0.1 0.3 0.6 0.4 -0.3 0.5 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 3.3 1.6 -1.8 1.1 -1.0 1.2 -1.4 0.9 0.2 0.8
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 4.1 0.5 -0.6 -0.0 -1.1 2.0 -1.7 -0.2 0.7 0.6
Qualifications: CSEs or equivalent 1.3 1.7 5.7 -1.6 2.4 -1.2 0.9 -0.1 0.1 -1.4 -1.1 -1.3
Serious illness, injury or assault to yourself 2.6 3.2 6.4 -2.5 2.3 -1.5 1.9 0.9 0.8 -1.7 -1.6 -2.0
High blood pressure 0.3 0.9 2.8 1.1 -0.8 0.9 -1.4 -0.0 -1.7 0.4 -0.1 0.5
Hayfever, allergic rhinitis or eczema 0.4 1.0 3.7 -0.1 1.0 -0.4 0.8 -1.9 1.2 -0.9 -0.7 -0.8
Multivitamins +/- minerals 2.2 2.8 5.6 2.4 -2.3 1.4 -1.5 -0.8 -0.0 1.9 1.3 2.0
Stomach or abdominal pain in last month 0.3 0.3 1.8 0.5 0.2 0.2 -0.6 1.4 -0.6 0.2 0.5 0.0
Supplements: Glucosamine 0.1 0.1 0.4 -0.4 -0.0 -0.3 -0.1 -0.4 0.6 0.4 -0.5 0.2
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.4 0.1 0.0 -0.7 0.3 1.6 -0.7 -1.1 -0.9 -0.7
Medication: Atenolol 1.1 1.4 2.4 -0.6 1.5 -1.1 1.0 1.1 -1.0 -1.1 -1.2 -1.6
Medication: Levothyroxine sodium 1.1 1.9 4.5 -1.3 2.0 -0.8 0.5 2.1 -0.9 -1.9 -0.1 -1.1
Sitting height 0.7 4.9 10.6 2.0 -3.2 2.3 -2.3 -2.3 0.8 1.9 1.7 2.5
Chronic bronchitis/emphysema (father) 0.4 0.5 1.8 0.5 -1.2 -0.3 0.9 0.4 1.3 0.3 0.2 -0.1
High blood pressure (mother) 1.4 2.0 3.6 1.5 -1.8 1.0 -1.9 -1.8 -1.2 0.9 0.6 1.2
Body mass index (BMI) 3.8 16.0 34.6 -4.5 4.9 -4.4 3.2 1.5 0.1 -5.9 -3.6 -4.5
Impedance of leg (left) 0.1 0.4 0.9 -0.9 0.6 -0.7 0.4 0.5 -0.5 0.2 -1.0 -0.6
Leg predicted mass (left) 0.6 3.1 8.9 -2.4 1.5 -1.7 1.1 0.3 1.1 -3.0 -1.5 -1.7
Trunk fat mass 4.1 17.5 34.1 -5.3 4.5 -4.6 3.3 1.9 0.1 -5.8 -4.2 -4.7
Waist circumference 4.5 16.5 35.4 -5.0 4.7 -4.6 2.8 0.5 -0.1 -6.0 -4.1 -4.5
Number of incorrect matches in round 0.8 1.3 3.1 0.3 -1.0 0.6 -1.5 -1.8 -1.3 1.2 0.0 1.2
Past tobacco smoking 1.2 2.3 4.9 2.2 -1.1 2.0 -1.1 -0.7 -1.2 1.6 1.9 1.2
Alcohol usually taken with meals 7.9 12.8 25.3 4.5 -5.0 3.5 -3.2 -1.2 0.5 3.8 3.7 4.2
Nervous feelings 0.6 1.2 2.2 1.4 -1.5 1.2 -0.6 -1.1 1.0 1.0 0.6 1.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.2 -0.1 -0.4 -0.4 -0.0 0.5 0.1 -0.5 -0.5 -0.1
Hearing difficulty/problems with background noise 0.0 0.1 0.2 0.4 -0.2 -0.0 -0.4 0.0 -0.3 0.3 0.4 0.0
Hair/balding pattern: Pattern 2 1.3 1.7 4.6 -2.2 1.5 -1.0 -0.1 1.8 -1.0 -1.2 -1.1 -0.5
Had menopause 0.6 0.7 3.9 0.8 0.5 -0.6 -0.6 0.6 -2.0 0.3 -0.6 0.1
Had other major operations 0.4 0.5 1.7 -0.5 1.3 -0.9 0.5 -1.3 0.2 -0.1 0.1 -0.4
Forced vital capacity (FVC) 0.5 1.9 7.5 -2.7 0.6 0.2 -0.2 -1.9 1.5 0.1 -1.7 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.1 4.8 1.4 -2.2 1.4 -1.5 1.3 -1.9 1.0 0.4 1.0
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 2.3 -1.2 1.5 -1.1 0.6 -0.2 -0.1 -0.9 -0.6 -0.7
Qualifications: None of the above 9.9 21.2 33.6 -4.7 5.8 -5.4 3.5 3.4 -3.1 -5.5 -4.1 -5.1
Financial difficulties in last 2 years 7.5 10.0 15.7 -3.9 3.2 -3.4 2.8 -0.7 -0.0 -4.0 -3.9 -3.7
Mouth/teeth dental problems 0.6 1.0 1.8 0.8 -1.4 1.1 -1.0 -0.6 -0.5 1.2 0.7 1.2
Heart attack 4.7 6.0 9.6 -2.5 3.1 -2.8 2.5 0.3 0.9 -3.1 -2.4 -2.8
Allergy 0.3 0.7 2.4 -0.8 -1.2 -0.2 -0.5 1.5 -0.8 0.5 0.0 0.5
Pain all over the body in last month 0.6 0.7 1.7 -0.2 1.1 -0.8 0.3 0.4 -1.3 -1.1 -0.6 -0.8
Diabetes (self-reported) 0.8 1.3 2.7 -0.6 1.7 -1.5 1.2 -0.2 0.7 -1.5 -0.7 -1.2
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 1.6 -0.5 1.3 -1.3 1.3 -1.2 1.1 -1.1 -0.9 -1.1
Medication: Ramipril 0.6 0.7 2.4 1.5 -0.7 0.9 -0.8 -0.3 -0.2 0.7 0.8 0.8
Medication: Simvastatin 1.4 2.0 5.1 -1.5 1.4 -1.6 0.7 -1.1 -0.6 -1.4 -2.2 -1.4
Fluid intelligence score 7.5 15.7 32.3 3.2 -5.7 5.1 -3.8 -0.8 0.5 4.9 3.7 4.5
Illnesses of siblings 0.5 0.6 1.4 0.6 -1.0 0.4 -0.1 -1.1 1.2 0.7 0.9 0.6
Neuroticism score 0.1 0.1 0.5 0.3 -0.7 -0.0 -0.2 0.4 -0.0 -0.3 0.3 0.0
Weight 2.3 11.2 26.3 -4.4 3.7 -3.6 2.3 0.8 0.6 -5.1 -3.2 -3.5
Impedance of arm (right) 0.4 2.0 5.7 1.3 -2.4 1.6 -0.8 0.8 0.3 2.1 0.6 1.3
Arm fat percentage (right) 3.6 14.1 29.4 -4.2 4.3 -4.1 3.2 2.4 0.1 -5.4 -3.3 -4.3
Trunk fat-free mass 0.2 1.2 3.9 -2.0 0.9 -0.9 0.2 -0.3 1.0 -1.9 -0.4 -0.6
Hip circumference 2.8 12.1 27.8 -4.0 3.7 -3.9 2.9 0.6 1.6 -5.3 -3.2 -3.8
Time employed in main current job 0.4 0.5 2.0 0.6 -0.9 1.4 -0.1 0.0 -0.4 0.8 0.6 0.4
Alcohol intake versus 10 years previously 1.0 1.5 2.3 -1.4 1.4 -1.5 0.4 1.5 -0.3 -1.5 -1.2 -1.4
Father’s age at death 2.6 3.5 5.7 2.0 -2.4 1.9 -0.3 -0.6 2.0 2.3 2.1 2.1
Worrier / anxious feelings 1.5 2.9 7.3 2.7 -2.1 1.7 -1.3 -0.5 1.0 1.3 1.8 1.9
Frequency of tiredness / lethargy in last 2 weeks 2.2 3.6 7.1 -2.3 2.7 -2.5 1.6 0.2 0.5 -2.4 -1.6 -1.7
Falls in the last year 1.4 1.9 8.9 1.3 -0.2 0.3 -1.9 0.2 -3.0 1.2 0.6 1.0
Hair/balding pattern: Pattern 3 5.0 7.4 14.1 3.3 -3.8 3.0 -2.6 -1.1 -0.6 3.0 2.5 3.0
Number of live births 0.6 0.8 1.2 1.1 -1.0 0.3 -1.1 -0.8 -0.9 0.9 0.8 0.9
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 6.9 -2.6 1.0 0.4 -0.0 -1.7 1.8 0.4 -1.2 0.1
Pulse rate 0.2 0.3 1.4 -0.0 0.1 0.0 0.3 1.2 -0.5 -0.3 0.7 -0.3
Happiness 1.3 1.6 6.0 1.0 -0.8 0.5 -1.4 -2.5 -0.8 1.1 0.7 1.4
Noisy workplace 2.5 3.1 6.3 -1.3 1.6 -2.5 1.5 0.1 0.2 -2.4 -2.2 -2.1
Qualifications: A levels/AS levels or equivalent 10.0 22.2 37.0 5.4 -5.1 6.1 -3.3 -3.3 2.9 5.6 4.3 5.2
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.2 0.5 -0.5 -0.7 -0.1 0.2 -0.7 0.2 -0.3 0.2 -0.1
Mouth/teeth dental problems: Dentures 0.3 0.5 2.2 1.5 -0.8 0.1 -0.2 1.2 -0.2 -0.3 0.4 -0.2
Asthma 0.4 0.9 3.9 0.9 2.0 0.0 -0.1 -0.8 -0.9 -0.7 -0.5 -1.0
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 6.4 -0.6 -0.1 -0.3 1.6 1.5 2.5 -0.6 0.7 -0.2
Medication: Cholesterol lowering 1.1 1.7 3.2 -1.3 1.8 -1.2 1.1 -0.9 0.3 -1.3 -1.7 -1.4
Depression (self-reported) 0.7 0.8 2.6 -1.0 0.6 -0.9 -0.6 0.1 -1.0 -0.9 -1.6 -0.4
Medication: Lansoprazole 0.5 0.6 1.5 1.2 -0.2 0.4 -1.0 0.1 -1.1 0.7 0.6 0.8
Prospective memory result 0.5 0.7 1.2 -0.6 0.5 -0.9 0.8 0.9 -0.6 -1.1 -0.7 -1.1
Lung cancer (father) 0.4 0.4 1.3 0.1 1.0 -0.6 1.0 -0.3 1.2 -0.0 -0.1 -0.2
Illnesses of mother 0.3 0.4 0.9 -0.4 1.0 -0.8 0.7 0.8 0.5 -0.1 0.5 -0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 4.9 -2.2 0.7 0.8 -0.3 -1.0 1.9 0.6 -0.6 0.4
Pulse wave Arterial Stiffness index 0.7 0.8 4.3 1.0 -0.5 0.5 -1.3 -0.4 -2.1 0.3 0.1 0.3
Impedance of arm (left) 0.6 2.7 6.5 1.6 -2.5 2.0 -1.1 0.8 0.2 2.3 1.0 1.7
Arm fat mass (right) 3.7 15.4 34.1 -4.6 4.4 -4.3 3.3 2.0 0.7 -5.8 -3.4 -4.4
Trunk predicted mass 0.2 1.2 3.8 -2.0 0.9 -0.8 0.2 -0.2 1.1 -1.9 -0.4 -0.6
Standing height 0.1 1.1 3.0 -0.9 -1.7 0.7 -1.5 -1.0 0.9 0.4 -0.0 1.2
Length of working week for main job 1.3 1.5 3.1 1.3 -1.8 0.7 -1.4 -0.8 -0.2 1.1 1.1 1.7
Exposure to tobacco smoke at home 0.6 0.7 1.3 -0.9 0.7 -0.7 0.8 0.9 -0.2 -0.7 -1.0 -1.1
Breastfed as a baby 0.5 0.6 1.8 0.2 -0.5 -0.9 -0.3 -1.3 -0.9 0.3 -1.1 0.0
Tense / ‘highly strung’ 0.2 0.4 0.8 -0.7 -0.1 -0.4 0.3 -0.8 0.6 -0.7 -0.9 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 3.8 -1.5 0.5 -1.4 0.4 1.9 -1.0 -1.5 -1.1 -1.4
Hair/balding pattern: Pattern 4 0.2 0.4 1.6 -0.5 -0.4 0.2 0.8 0.6 1.3 0.2 -0.2 -0.5
Birth weight of first child 0.1 0.2 0.5 0.6 -0.5 -0.3 0.1 -0.7 -0.1 0.4 0.7 0.2
Peak expiratory flow (PEF) 0.4 0.9 3.7 -0.7 0.4 1.0 -0.6 -1.9 0.9 0.8 -0.5 0.4
Pulse wave reflection index 0.7 0.8 3.2 0.7 -0.3 -0.1 -0.6 -1.4 -1.8 0.4 -1.1 -0.1
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.3 -1.1 0.6 -0.8 0.4 0.7 -1.0 -1.1 -0.5 -1.0
Loud music exposure frequency 1.3 1.4 4.0 0.6 -0.9 0.8 -1.9 0.3 -2.0 0.7 1.2 1.0
Qualifications: O levels/GCSEs or equivalent 3.6 5.8 9.8 3.1 -1.9 2.3 -2.2 -3.1 0.5 2.7 2.1 2.6
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 3.0 -1.3 1.2 -1.0 1.5 0.0 0.9 -1.7 -0.6 -1.4
Blood clot in the leg (DVT) 2.3 3.0 7.5 1.6 -1.1 2.7 -0.6 -0.7 1.0 1.8 2.6 1.9
Medication: Paracetamol 0.7 1.1 2.4 -0.5 1.0 -1.4 1.0 0.3 0.6 -1.6 -1.3 -1.2
Headache pain in last month 0.1 0.2 1.7 -0.0 1.3 -0.1 -0.1 -0.4 0.3 0.3 0.1 -0.1
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 3.1 1.0 -1.2 0.6 -0.3 0.2 0.8 1.0 1.8 1.1
Glaucoma (self-reported) 0.6 0.7 2.4 -0.7 0.5 -0.5 -0.3 -0.7 -1.6 -0.3 -1.2 -0.8
Gout (self-reported) 1.4 1.9 3.1 1.4 -1.7 1.4 -1.0 1.1 0.5 1.5 1.8 1.6
Hypothyroidism/myxoedema (self-reported) 2.2 4.2 10.5 -2.3 3.2 -1.4 1.1 2.1 -1.4 -2.7 -1.2 -2.0
Medication: Amlodipine 0.1 0.1 0.4 0.0 -0.3 -0.2 0.7 -0.1 0.7 0.2 0.4 -0.1
Medication: Ventolin 100micrograms inhaler 0.6 0.8 3.9 0.2 2.0 -0.7 -0.1 -0.8 -0.7 -0.7 -0.7 -0.9
Birth weight 0.7 1.5 5.0 -2.2 0.7 -1.2 1.0 -0.2 0.2 -1.3 -1.5 -1.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.7 -0.6 0.4 -0.7 -0.6 1.4 -1.6 -0.7 -0.3 -0.5
High blood pressure (siblings) 0.7 1.0 1.8 1.2 -0.9 1.0 -1.3 0.5 -1.3 1.1 0.3 1.0
Forced vital capacity (FVC), Best measure 0.4 1.3 4.2 -2.0 0.3 0.7 -0.3 -1.4 1.9 0.5 -1.0 0.3
Body fat percentage 5.1 20.1 37.7 -5.3 5.0 -5.0 3.6 2.3 -0.2 -6.1 -4.4 -5.1
Leg fat percentage (right) 5.5 19.8 36.7 -5.2 5.6 -5.1 3.6 1.5 -0.3 -6.1 -4.1 -4.9
Arm fat-free mass (right) 0.9 4.8 12.1 -3.2 2.4 -2.4 1.1 0.1 0.2 -3.5 -1.8 -2.1
Exposure to tobacco smoke outside home 0.6 0.8 1.7 1.3 -1.0 0.8 0.3 0.9 1.1 0.7 1.1 0.4
Comparative body size at age 10 1.6 4.4 9.2 1.5 -2.5 3.0 -2.1 -0.5 1.1 2.1 2.2 2.7
Number of full brothers 3.0 3.7 6.6 -2.1 2.1 -2.6 0.4 0.8 -2.2 -2.3 -2.0 -1.8
Worry too long after embarrassment 0.5 0.8 3.7 -0.1 -1.0 -0.2 -0.6 -1.9 1.0 0.5 0.3 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.6 1.7 0.4 -0.4 0.3 -1.3 -0.6 -0.5 0.8 0.8 1.0
Wheeze or whistling in the chest in last year 2.0 3.5 12.0 -1.5 3.5 -2.1 1.4 0.0 -0.5 -2.0 -1.3 -2.3
Number of children fathered 0.1 0.1 0.2 -0.0 0.3 -0.0 -0.1 -0.2 -0.2 0.4 0.4 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.6 0.1 -0.7 0.5 -0.1 0.6 -0.4 0.5 -0.7 -0.3
Age at first live birth 2.5 4.5 8.5 2.9 -2.0 2.8 0.0 -1.1 2.2 2.5 2.0 1.8
Pulse wave peak to peak time 0.7 0.8 4.0 -1.0 0.4 -0.5 1.1 0.5 2.0 -0.4 -0.0 -0.2
Health satisfaction 0.4 0.5 1.5 -0.7 1.1 -0.4 0.0 -1.2 -0.0 -0.7 -0.6 -0.3
Shortness of breath walking on level ground 0.8 0.9 1.5 -0.4 1.1 -1.2 0.7 0.9 -1.0 -1.0 -0.8 -1.2
Qualifications: College or University degree 10.7 33.7 59.2 6.9 -7.7 7.1 -4.2 -2.6 1.7 6.9 5.4 6.4
Eye problems/disorders: None of the above 0.7 0.8 4.1 -0.8 1.2 -0.1 0.8 -0.3 2.0 -0.3 0.2 -0.0
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.9 -0.0 -0.4 0.9 -0.4 -0.3 0.1 1.0 0.1 0.2
Emphysema/chronic bronchitis 0.6 0.6 2.7 -0.6 1.0 0.2 0.9 1.6 0.0 -0.1 0.8 -0.5
Medication for pain relief, constipation, heartburn 0.9 1.5 2.7 0.5 -1.4 1.2 -1.7 -0.7 -0.6 1.5 1.3 1.5
Neck or shoulder pain in last month 0.6 0.9 2.2 0.6 1.0 -1.1 1.5 0.5 1.5 -0.1 -0.4 -0.8
Medication: Blood pressure 0.2 0.4 1.6 0.1 0.7 -0.1 -0.2 -0.3 -1.0 -0.2 -1.3 -0.4
Angina (self-reported) 1.9 2.5 5.2 -1.4 2.3 -1.6 1.3 0.5 -0.0 -2.0 -1.8 -1.9
Migraine (self-reported) 0.3 0.4 0.8 -0.2 0.9 -0.7 0.9 -0.8 0.1 -0.1 -0.4 -0.8
Medication: Ibuprofen 0.9 1.0 3.4 -0.5 -0.4 -0.1 1.2 1.9 1.8 -0.5 0.8 -0.1
Medication: Allopurinol 2.5 3.4 5.8 2.3 -2.0 2.1 -1.3 0.8 0.0 2.1 2.4 2.0
Medication: Omeprazole 0.8 1.0 3.6 -0.6 1.9 -0.9 1.0 1.1 -0.2 -0.5 -0.6 -1.1
Medication: Seretide 50 evohaler 0.2 0.3 1.2 0.2 1.1 0.4 0.2 -0.8 -0.5 -0.1 0.2 -0.2
Mean time to correctly identify matches 0.4 0.8 2.0 1.4 -1.0 0.4 -0.9 -0.3 -1.4 0.7 0.4 0.5
Heart disease (mother) 0.7 0.8 1.3 1.1 -1.1 1.0 -0.8 0.9 0.2 0.5 1.0 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.5 1.8 4.0 0.9 -1.5 2.0 -1.2 -0.4 0.3 1.7 1.5 1.4
Whole body fat mass 4.4 18.2 37.2 -5.3 4.6 -4.8 3.3 2.1 0.1 -6.1 -4.0 -4.8
Leg fat mass (right) 5.1 19.8 39.3 -5.4 5.3 -5.0 3.7 1.6 0.3 -6.3 -4.1 -5.0
Arm predicted mass (right) 1.0 5.1 12.4 -3.3 2.5 -2.4 1.4 -0.1 0.6 -3.5 -1.9 -2.2
Pulse rate, automated reading 0.2 0.5 1.1 -0.5 0.8 -1.0 0.6 0.6 -0.6 -1.1 0.2 -0.8
Alcohol intake frequency. 1.1 2.6 5.2 -1.4 2.1 -1.7 1.6 0.1 0.0 -2.3 -1.1 -2.2
Comparative height size at age 10 0.5 2.7 7.9 1.0 -1.9 1.3 -2.8 -0.4 -1.5 1.1 0.8 2.4
Number of full sisters 1.2 1.5 7.7 0.1 0.7 -0.7 -0.7 1.9 -2.8 -0.8 -0.0 -0.4
Suffer from ‘nerves’ 0.4 0.7 3.0 1.7 -1.0 0.7 -0.7 -0.4 0.2 0.6 0.6 0.6
Overall health rating 1.1 2.3 4.5 -1.2 2.1 -2.1 1.2 0.7 -0.9 -1.8 -1.0 -1.8
Chest pain or discomfort 0.4 0.6 1.8 -0.3 1.3 -0.4 0.9 0.5 -0.0 -1.0 -0.2 -1.1
Had major operations 0.5 0.6 2.4 0.1 -0.1 0.5 -1.2 0.0 -1.6 0.8 -0.3 0.7
Age at last live birth 6.0 8.8 14.7 3.8 -2.4 3.7 -1.0 -2.0 2.5 3.8 3.0 3.1
Family relationship satisfaction 0.9 1.1 3.0 1.1 -0.6 0.9 -0.2 -1.6 0.4 0.9 1.7 1.0
Leg pain on walking 3.0 3.8 6.1 -1.9 2.3 -2.5 1.0 -0.5 -2.1 -2.4 -1.8 -2.1
Qualifications: NVQ or HND or HNC or equivalent 1.7 2.0 6.9 -2.6 1.8 -1.2 0.7 1.3 -0.0 -1.5 -0.5 -1.3
Commuting to job workplace: Car/motor vehicle 8.6 9.9 15.8 -4.0 3.9 -2.8 3.6 0.8 1.2 -3.6 -2.9 -3.7
Illness, injury, bereavement, stress in last 2 years 2.5 3.1 5.9 2.4 -1.2 1.9 -1.6 -0.6 -0.3 2.2 2.2 2.0
Medication: Aspirin 0.3 0.4 0.9 -0.0 0.8 -0.1 0.7 -0.5 0.0 -0.8 -0.9 -0.7
Supplements: Vitamin C 0.6 0.7 1.4 0.6 -0.9 0.7 -0.9 -1.0 0.1 0.9 1.0 1.2
Knee pain experienced in last month 1.8 2.8 4.9 -2.2 1.9 -1.7 0.6 1.5 -1.4 -2.2 -1.1 -1.9
Hypertension (Self-reported) 0.3 0.7 2.1 1.0 -0.7 1.0 -1.3 -0.2 -1.5 0.4 -0.1 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.8 0.8 0.2 0.2 0.3 0.9 -0.6 0.4 0.5 -0.1
Illnesses of father: Heart disease 3.3 4.5 10.1 2.5 -1.4 3.2 -1.6 -0.9 -0.1 2.8 2.2 2.5
Illnesses of siblings: Diabetes 1.9 2.4 4.8 -1.7 2.0 -2.2 1.4 -0.3 -0.1 -1.6 -1.4 -1.7
Smoking status: Previous 1.3 1.9 6.2 -2.5 0.7 -1.6 0.9 1.4 1.1 -1.3 -1.2 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.1 0.1 -0.3 1.1 0.0 0.1 1.0 0.3 0.0 0.3
Whole body fat-free mass 0.4 2.4 7.2 -2.4 1.4 -1.5 0.7 -0.1 1.0 -2.7 -1.2 -1.3
Leg fat-free mass (right) 0.4 2.1 6.7 -1.9 1.1 -1.4 0.8 -0.1 1.2 -2.6 -1.4 -1.4
Arm fat percentage (left) 3.6 14.4 30.5 -4.3 4.3 -4.2 3.2 2.3 0.2 -5.5 -3.3 -4.2
Average weekly red wine intake 4.8 7.1 12.8 3.0 -3.6 3.1 -2.1 -0.8 1.2 2.9 2.8 3.2
Handedness (chirality/laterality): Left-handed 0.3 0.4 0.6 -0.5 0.3 -0.5 0.6 -0.7 0.8 -0.8 -0.5 -0.6
Mood swings 0.6 1.1 2.8 -1.3 0.9 -1.2 0.5 0.7 -0.5 -1.7 -0.8 -1.1
Loneliness, isolation 1.0 1.4 3.3 -0.7 1.3 -1.6 0.9 1.8 -0.5 -1.5 -0.1 -1.2
Long-standing illness, disability or infirmity 0.7 1.1 2.5 -0.2 1.2 -0.6 -0.4 -1.4 -1.6 -0.9 -1.5 -0.4
Ever had bowel cancer screening 0.4 0.4 1.7 -0.2 -0.8 -0.1 0.7 -0.8 1.3 0.2 0.6 0.1
Diabetes diagnosed by doctor 0.6 1.0 2.2 -0.6 1.3 -1.5 1.0 0.4 0.2 -1.4 -0.8 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.6 5.9 1.6 -1.2 1.1 -2.3 -0.6 -0.4 1.9 1.7 2.4
Friendships satisfaction 3.8 4.7 6.6 2.0 -2.4 1.6 -2.6 -2.3 -1.3 2.2 2.2 2.5
Qualifications: nursing, teaching 4.3 6.7 9.6 2.6 -2.7 3.1 -0.9 -2.9 2.9 3.0 1.9 2.4
Commuting to job workplace: Walk 6.1 6.6 13.4 3.7 -2.7 2.7 -2.0 -1.6 -0.6 2.6 3.0 2.9
Eye problems/disorders: Cataract 4.6 5.3 9.7 -1.9 1.8 -3.0 2.4 1.2 -0.3 -2.9 -2.6 -3.1
Mouth/teeth dental problems: Mouth ulcers 1.6 2.6 8.8 -1.8 3.0 -1.8 0.6 -0.2 -1.3 -1.1 -1.8 -1.2
Medication for cholesterol 0.6 1.0 3.8 -0.7 1.0 -0.3 1.4 0.8 1.9 0.2 0.8 -0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.1 0.4 -0.3 0.1 0.4 -0.4 0.0 0.2 -0.1 -0.2
Back pain experienced in last month 1.0 1.4 3.7 -1.0 0.9 -1.3 0.9 -1.9 1.5 -1.1 -1.0 -0.5
Mineral and other dietary supplements 0.6 0.8 2.2 -0.0 0.4 -0.8 1.5 0.7 0.1 -1.3 -0.1 -1.4
Breast cancer (self-reported) 0.1 0.1 0.6 -0.4 -0.1 0.2 -0.2 0.1 -0.8 0.1 0.2 -0.2
Asthma (self-reported) 0.5 1.0 4.5 0.5 2.1 -0.3 0.1 -0.8 -0.8 -1.0 -0.8 -1.2
Osteoporosis (self-reported) 0.2 0.3 0.7 0.8 -0.2 -0.2 0.2 -0.8 0.9 0.2 0.6 0.4
Osteoarthritis (self-reported) 0.2 0.3 1.2 -0.3 -0.5 -0.1 -0.7 -0.0 -1.1 -0.6 0.2 0.2
Medication: Aspirin 0.8 1.0 1.9 -0.5 1.4 -0.7 1.0 -0.6 0.5 -1.4 -1.4 -1.1
Medication: Gliclazide 0.3 0.3 0.7 0.2 0.1 -0.6 0.7 0.8 0.1 -0.8 -0.1 -0.6
Illnesses of father: None of the above (group 1) 0.4 0.4 1.4 -0.6 -0.7 -0.5 -0.8 -1.2 -0.4 -0.1 -0.8 0.1
Smoking status: Current 1.7 2.8 4.9 -1.5 2.0 -1.8 0.8 0.7 -2.2 -1.7 -1.9 -1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.5 -1.6 -0.0 0.7 -0.5 -0.8 0.8 0.6 -1.1 0.1
Whole body water mass 0.4 2.5 7.3 -2.4 1.4 -1.5 0.8 0.0 1.1 -2.7 -1.2 -1.4
Leg predicted mass (right) 0.4 2.1 6.7 -1.9 1.0 -1.4 0.8 -0.1 1.2 -2.6 -1.3 -1.3
Arm fat mass (left) 3.9 16.0 35.3 -4.8 4.6 -4.4 3.2 2.0 0.5 -5.9 -3.5 -4.4
Number of self-reported non-cancer illnesses 0.5 0.9 2.9 -0.3 0.9 -0.5 -0.1 -0.7 -1.7 -1.2 -1.0 -0.8
Average weekly champagne plus white wine intake 1.1 1.5 3.7 1.2 -1.4 1.3 -1.0 0.1 -0.1 1.9 1.4 1.3
Miserableness 0.2 0.3 1.0 -0.4 1.0 -0.8 0.5 0.1 -0.0 -0.8 0.1 -0.7
Guilty feelings 5.4 8.2 13.7 3.4 -3.7 3.4 -2.6 1.0 -0.4 2.9 3.1 3.2
Wears glasses or contact lenses 0.9 1.1 3.6 -1.0 1.0 -1.2 0.4 -0.8 -0.6 -0.6 -1.9 -1.0
Ever taken oral contraceptive pill 0.4 0.5 0.8 -0.9 0.8 -0.5 0.8 0.6 0.6 -0.6 -0.6 -0.8
Hearing aid user 1.3 1.5 3.8 1.1 -1.8 1.0 -1.1 -1.9 0.3 1.3 -0.2 0.9
Mother’s age at death 1.6 2.0 4.2 1.4 -2.0 1.6 -0.6 1.6 1.1 1.2 1.6 1.1
Financial situation satisfaction 1.0 1.3 2.5 -1.2 1.2 -1.4 -0.2 0.0 -1.2 -1.6 -1.3 -0.9
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.3 -1.1 0.3 -0.8 0.9 -0.0 1.0 -0.7 -1.1 -1.0
Commuting to job workplace: Public transport 12.0 14.4 22.4 4.5 -4.6 3.9 -3.5 -0.6 -0.3 4.7 4.3 4.5
Eye problems/disorders: Glaucoma 1.0 1.2 8.3 0.2 -0.6 0.2 -1.4 0.0 -2.9 0.5 -0.5 -0.0
Medication: Blood pressure 0.3 0.6 3.6 0.3 -0.5 0.2 -0.5 -0.5 -1.9 -0.6 -0.7 -0.5
Pain type(s) experienced in last month: Hip pain 0.5 0.7 1.6 -0.6 0.7 -0.4 1.1 -0.6 0.2 -0.8 -1.3 -1.1
Supplements: Fish oil (including cod liver oil) 2.0 2.6 5.8 0.8 -1.5 1.5 -1.9 0.1 0.0 2.4 1.6 2.4
High cholesterol (Self-reported) 0.6 1.0 2.6 -1.2 1.1 -0.7 0.8 -0.2 0.1 -0.9 -1.6 -1.3
Medication: Bendroflumethiazide 0.2 0.3 0.9 -0.2 0.1 0.3 0.5 0.2 0.5 -0.4 -1.0 -0.9
Medication: Paracetamol 0.6 0.9 1.9 -0.2 1.1 -1.1 0.8 0.3 0.5 -1.4 -1.1 -1.1
Medication: Lisinopril 0.6 0.7 1.8 0.3 0.2 -0.2 0.0 1.0 -1.4 -1.3 -1.0 -1.0
Medication: Atorvastatin 0.5 0.6 1.1 0.4 0.8 -0.9 1.0 -0.4 0.4 -0.7 -0.8 -1.0
Illnesses of father: High blood pressure 0.8 1.0 2.0 -0.3 0.7 -0.1 1.4 0.6 1.3 -1.1 -1.3 -1.4
Alcohol drinker status: Never 1.8 2.2 4.5 -1.4 1.3 -1.5 1.7 0.7 -0.6 -1.4 -1.8 -2.1
Ever smoked 0.4 0.8 2.2 -1.1 0.4 -1.2 0.4 -0.0 0.7 -1.0 -1.5 -0.6
Basal metabolic rate 0.7 4.1 11.2 -2.9 2.0 -2.0 1.2 0.2 1.1 -3.3 -1.6 -1.9
Leg fat percentage (left) 5.5 19.7 36.4 -5.1 5.5 -5.3 3.6 1.2 -0.2 -6.0 -4.3 -5.0
Arm fat-free mass (left) 1.1 5.3 12.8 -3.4 2.6 -2.5 1.3 0.1 0.5 -3.6 -2.0 -2.3
Number of operations (self-reported) 0.4 0.6 1.8 -0.0 0.5 -0.9 -0.6 -1.3 -1.0 -0.3 -0.9 -0.2
Average weekly beer plus cider intake 1.4 2.0 5.2 -2.2 1.1 -1.0 0.0 2.3 -1.2 -1.4 -1.1 -1.1
Irritability 1.1 1.9 4.4 -2.1 1.1 -1.0 1.2 -0.8 0.1 -1.5 -1.9 -1.6
Risk taking 1.9 2.8 4.9 -1.2 0.3 -2.0 2.2 2.1 1.1 -1.8 -1.5 -1.9
Ever had prostate specific antigen (PSA) test 1.4 1.6 4.6 0.9 -1.6 1.4 -0.5 -2.1 1.0 0.9 1.1 1.1
Fractured/broken bones in last 5 years 0.8 1.0 2.6 -0.8 0.8 -1.6 0.6 -0.1 -0.5 -1.6 -1.0 -0.9
Age started oral contraceptive pill 3.0 3.7 9.4 2.6 -3.1 2.4 -0.7 0.1 0.0 2.2 2.0 1.5
Diastolic blood pressure, automated reading 0.5 1.4 5.8 1.6 -0.0 0.4 0.2 2.4 0.4 0.3 1.9 0.5
Ever depressed for a whole week 1.2 1.5 4.9 -1.5 2.2 -0.9 0.7 0.8 -0.8 -1.2 -0.8 -1.3
Unable to work because of sickness or disability 0.5 0.7 1.9 0.6 -0.3 0.1 -1.4 0.5 -1.3 0.9 0.1 1.1
Commuting to job workplace: Cycle 1.5 1.8 8.0 1.2 -1.5 0.4 -1.4 -2.8 0.2 0.6 -0.9 0.9
Myopia 0.8 1.2 4.8 0.5 -0.8 1.3 0.2 0.3 2.2 0.7 1.4 1.0
Vascular/heart problems diagnosed by doctor 0.3 0.7 3.7 0.0 -0.2 -0.1 1.0 0.3 1.9 0.5 1.1 0.2
Cholesterol lowering medication 1.3 1.9 3.9 -0.8 1.3 -1.6 1.2 -0.2 -0.8 -1.8 -2.0 -1.8
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 2.7 -0.0 1.6 -0.3 0.7 1.5 -0.1 0.2 0.0 -0.7
Pain experienced in last month 0.6 1.1 2.2 1.1 -1.5 1.0 -1.1 -1.2 -0.5 0.9 0.6 1.1
Supplements: Calcium 0.4 0.4 0.8 -0.7 0.6 0.5 -0.7 -0.9 0.2 0.5 0.7 0.7
Basal cell carcinoma (self-reported) 0.6 0.7 1.2 0.5 -1.0 0.9 -1.1 -0.5 -1.0 0.9 0.3 0.8
Heart attack/myocardial infarction (self-reported) 5.1 6.6 10.8 -2.6 3.3 -3.0 2.6 0.2 0.6 -3.2 -2.5 -2.9
Deep venous thrombosis (DVT) (self-reported) 2.3 3.0 7.6 1.5 -1.2 2.8 -0.7 -0.5 0.9 1.8 2.6 2.0
Heart disease (siblings) 0.4 0.5 1.1 -0.8 1.0 -0.5 0.5 0.7 -0.3 -0.9 -0.2 -0.9
Alcohol drinker status: Previous 0.6 0.7 1.7 -1.1 0.1 -0.4 -1.3 -1.0 -1.1 -0.5 -1.0 0.1
Pack years of smoking 0.1 0.1 0.5 0.7 0.1 -0.0 0.3 0.2 -0.3 -0.2 0.6 -0.1
Impedance of whole body 0.1 0.6 2.0 0.3 -1.1 0.7 -0.4 0.9 -0.5 1.4 0.0 0.5
Leg fat mass (left) 5.1 19.7 39.2 -5.2 5.2 -5.1 3.7 1.4 0.4 -6.3 -4.2 -5.0
Arm predicted mass (left) 1.1 5.5 13.1 -3.4 2.6 -2.5 1.4 0.3 0.4 -3.6 -2.0 -2.4