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chr6:108,612,536-110,710,018

Best TWAS P=1.73e-15 · Best GWAS P=1.19e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Prostate Adenocarcinoma	SESN1	0.02	0.04	lasso	4	0.04	1.1e-04	8.0	8.0	1.7e-15	1.00	0.02	0.97	TRUE
1	GTEx	Thyroid	RP11-425D10.10	0.20	0.05	enet	26	0.11	5.9e-09	-2.9	-5.3	1.1e-07	0.07	1.00	0.00	TRUE
2	NTR	Blood	SESN1	0.03	0.04	lasso	3	0.03	5.4e-11	7.9	7.9	2.0e-15	1.00	0.01	0.99	FALSE
5	YFS	Blood	SESN1	0.10	0.12	lasso	15	0.12	1.4e-36	7.9	7.9	3.1e-15	0.99	0.01	0.99	FALSE
6	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ARMC2	0.04	0.05	lasso	1	0.04	3.4e-04	7.2	-7.2	8.3e-13	-0.91	0.02	0.89	FALSE
7	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SESN1	0.17	0.01	blup	45	0.02	5.5e-02	8.0	-7.0	1.8e-12	-0.81	0.01	0.50	FALSE
9	The Cancer Genome Atlas	Rectum Adenocarcinoma	ARMC2	0.38	0.00	blup	88	0.08	7.2e-03	3.2	-6.5	6.3e-11	-0.67	0.01	0.21	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	CCDC162P	0.10	0.04	bslmm	398	0.07	1.1e-09	0.3	-6.0	1.5e-09	-0.52	0.89	0.07	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	AK9	0.08	0.06	bslmm	456	0.06	5.3e-08	-3.9	5.2	2.2e-07	0.04	1.00	0.00	FALSE