Best TWAS P=1.08e-07 · Best GWAS P=3.22e-08 conditioned to 0.052
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | RP11-73O6.3 | 0.29 | 0.08 | lasso | 5 | 0.10 | 5.7e-04 | 5.1 | 5.3 | 1.1e-07 | 0.84 | 0.02 | 0.94 | TRUE |
| 2 | GTEx | Colon Transverse | L3MBTL3 | 0.27 | 0.13 | lasso | 8 | 0.20 | 8.0e-10 | 4.4 | 5.3 | 1.2e-07 | 0.83 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Spleen | L3MBTL3 | 0.64 | 0.34 | enet | 14 | 0.48 | 6.4e-14 | 5.1 | 5.3 | 1.4e-07 | 0.82 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Spleen | RP11-73O6.3 | 0.45 | 0.43 | enet | 21 | 0.42 | 7.7e-12 | 5.1 | 5.2 | 2.6e-07 | 0.82 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | L3MBTL3 | 0.26 | 0.12 | lasso | 4 | 0.12 | 4.0e-07 | 4.8 | 5.1 | 2.8e-07 | 0.87 | 0.05 | 0.94 | FALSE |
| 6 | GTEx | Thyroid | L3MBTL3 | 0.40 | 0.39 | enet | 9 | 0.43 | 2.8e-35 | 4.4 | 5.1 | 3.0e-07 | 0.77 | 0.19 | 0.78 | FALSE |