Best TWAS P=2.46e-12 · Best GWAS P=2.04e-12 conditioned to 0.199
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | RABGAP1 | 0.09 | 0.07 | enet | 20 | 0.08 | 3.8e-10 | 6.3 | -6.1 | 1.1e-09 | -0.84 | 0.18 | 0.82 | FALSE |
2 | GTEx | Esophagus Muscularis | RABGAP1 | 0.10 | 0.01 | lasso | 5 | 0.03 | 3.7e-03 | 6.3 | -5.3 | 9.8e-08 | -0.78 | 0.11 | 0.74 | FALSE |
3 | GTEx | Skin Sun Exposed Lower leg | RABGAP1 | 0.05 | 0.01 | lasso | 4 | 0.02 | 4.1e-03 | 3.4 | 6.1 | 9.0e-10 | 0.80 | 0.08 | 0.78 | FALSE |
4 | GTEx | Testis | RABGAP1 | 0.13 | 0.04 | enet | 20 | 0.03 | 1.9e-02 | 7.0 | 5.3 | 1.1e-07 | 0.78 | 0.06 | 0.88 | FALSE |
5 | METSIM | Adipose | RABGAP1 | 0.04 | 0.03 | lasso | 9 | 0.05 | 1.2e-08 | 6.6 | -5.6 | 2.7e-08 | -0.80 | 0.08 | 0.92 | FALSE |
6 | YFS | Blood | RC3H2 | 0.02 | 0.01 | bslmm | 426 | 0.01 | 1.3e-04 | 3.6 | -5.4 | 7.8e-08 | -0.79 | 0.24 | 0.76 | FALSE |
7 | The Cancer Genome Atlas | Glioblastoma Multiforme | RABGAP1 | 0.17 | 0.17 | lasso | 7 | 0.21 | 5.6e-07 | 6.3 | 6.9 | 3.7e-12 | 0.90 | 0.03 | 0.96 | FALSE |
8 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RABGAP1 | 0.02 | 0.01 | blup | 56 | 0.01 | 7.4e-03 | 6.6 | 6.7 | 1.9e-11 | 0.92 | 0.05 | 0.67 | FALSE |
9 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | RABGAP1 | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.9e-03 | 6.7 | 6.9 | 5.8e-12 | 0.96 | 0.02 | 0.70 | FALSE |
10 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | RABGAP1 | 0.12 | 0.05 | blup | 58 | 0.06 | 4.2e-03 | 6.7 | 7.0 | 2.5e-12 | 0.94 | 0.04 | 0.92 | TRUE |