Best TWAS P=9.48e-12 · Best GWAS P=8.31e-13 conditioned to 0.0138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | EIF2S2P3 | 0.09 | 0.04 | lasso | 6 | 0.04 | 1.1e-03 | 7.1 | 6.4 | 1.6e-10 | 0.81 | 0.02 | 0.94 | FALSE |
| 2 | GTEx | Prostate | EIF2S2P3 | 0.21 | 0.05 | lasso | 4 | 0.11 | 1.1e-03 | 7.1 | 6.1 | 1.1e-09 | 0.78 | 0.02 | 0.68 | FALSE |
| 3 | GTEx | Spleen | EIF2S2P3 | 0.32 | 0.04 | enet | 15 | 0.11 | 1.2e-03 | 4.9 | 6.4 | 2.1e-10 | 0.82 | 0.02 | 0.75 | FALSE |
| 4 | GTEx | Testis | HHEX | 0.11 | 0.02 | enet | 8 | 0.00 | 4.2e-01 | 5.9 | 5.9 | 3.4e-09 | 0.70 | 0.08 | 0.30 | FALSE |
| 5 | GTEx | Thyroid | EIF2S2P3 | 0.15 | 0.14 | lasso | 2 | 0.14 | 6.2e-11 | 7.1 | 6.8 | 9.5e-12 | 0.88 | 0.01 | 0.99 | TRUE |
| 6 | NTR | Blood | KIF11 | 0.11 | 0.10 | lasso | 8 | 0.10 | 3.0e-29 | -5.3 | 5.6 | 2.1e-08 | 0.68 | 1.00 | 0.00 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | HHEX | 0.03 | 0.00 | blup | 28 | 0.02 | 1.4e-03 | 3.7 | 5.4 | 8.1e-08 | 0.66 | 0.01 | 0.32 | FALSE |