Best TWAS P=2.06e-09 · Best GWAS P=1.86e-07 conditioned to 0.101
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | RPS9 | 0.26 | 0.16 | enet | 17 | 0.18 | 7.3e-10 | -5.2 | 5.2 | 1.9e-07 | -0.87 | 0.00 | 1.00 | FALSE |
2 | GTEx | Artery Aorta | RPS9 | 0.39 | 0.27 | enet | 13 | 0.34 | 2.4e-19 | -5.2 | 5.5 | 4.7e-08 | -0.91 | 0.00 | 1.00 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | RPS9 | 0.25 | 0.12 | lasso | 8 | 0.17 | 1.4e-12 | 4.2 | 5.2 | 1.5e-07 | -0.82 | 0.04 | 0.95 | FALSE |
4 | GTEx | Colon Sigmoid | CTD-3093M3.1 | 0.28 | -0.01 | lasso | 8 | -0.01 | 6.8e-01 | -3.9 | -6.0 | 2.1e-09 | 0.10 | 0.03 | 0.30 | TRUE |
5 | GTEx | Esophagus Muscularis | RPS9 | 0.50 | 0.28 | lasso | 8 | 0.36 | 1.5e-22 | -5.2 | 5.5 | 3.3e-08 | -0.93 | 0.00 | 1.00 | TRUE |
6 | GTEx | Nerve Tibial | RPS9 | 0.37 | 0.19 | lasso | 12 | 0.23 | 2.8e-16 | -5.2 | 5.4 | 6.6e-08 | -0.93 | 0.00 | 1.00 | FALSE |