Best TWAS P=1.19e-15 · Best GWAS P=3.15e-15 conditioned to 0.00361
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP5-1085F17.3 | 0.14 | 0.04 | lasso | 5 | 0.06 | 1.1e-05 | -4.8 | 5.6 | 1.6e-08 | 0.33 | 0.65 | 0.04 | FALSE |
| 2 | GTEx | Muscle Skeletal | COMMD7 | 0.14 | 0.13 | lasso | 2 | 0.12 | 7.5e-12 | 7.7 | 7.7 | 1.3e-14 | 0.95 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Testis | COMMD7 | 0.11 | 0.01 | lasso | 4 | 0.01 | 1.3e-01 | 5.8 | 5.7 | 1.1e-08 | 0.73 | 0.06 | 0.62 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | COMMD7 | 0.04 | 0.01 | blup | 48 | 0.03 | 9.9e-04 | 5.8 | 5.4 | 6.8e-08 | 0.85 | 0.02 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | COMMD7 | 0.05 | 0.04 | blup | 48 | 0.03 | 5.2e-04 | -5.6 | -8.0 | 1.2e-15 | -0.74 | 0.02 | 0.77 | TRUE |