[Hub]/) : Traits : Birth weight :

chr17:25,295,032-26,338,912

Best TWAS P=1.4e-10 · Best GWAS P=2.13e-11 conditioned to 0.00611

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-173M1.8 0.58 0.18 enet 19 0.39 1.5e-22 2.2 5.2 2.3e-07 0.66 0.87 0.13 FALSE
2 GTEx Artery Coronary RP11-173M1.8 0.34 0.08 enet 17 0.21 1.1e-07 6.7 6.4 1.6e-10 0.73 0.01 0.98 FALSE
3 GTEx Cells Transformed fibroblasts RP11-173M1.8 0.33 0.10 lasso 6 0.26 1.6e-19 2.2 5.5 3.5e-08 0.71 0.08 0.92 FALSE
4 GTEx Esophagus Gastroesophageal Junction RP11-173M1.8 0.68 0.40 enet 8 0.43 6.6e-17 2.2 5.7 1.2e-08 0.66 0.98 0.02 FALSE
5 GTEx Esophagus Mucosa RP11-173M1.8 0.35 0.07 enet 17 0.19 7.8e-13 2.2 5.2 2.3e-07 0.67 0.07 0.92 FALSE
6 GTEx Esophagus Muscularis RP11-173M1.8 0.41 0.12 lasso 6 0.28 4.0e-17 2.2 5.9 3.5e-09 0.74 0.03 0.97 FALSE
7 GTEx Nerve Tibial RP11-173M1.8 0.45 0.11 enet 10 0.25 4.7e-18 2.2 5.3 9.3e-08 0.72 0.01 0.99 FALSE
8 GTEx Prostate RP11-173M1.8 0.27 0.23 enet 14 0.19 1.6e-05 6.3 6.4 1.4e-10 0.77 0.03 0.93 TRUE
9 GTEx Stomach RP11-173M1.8 0.32 0.09 enet 12 0.25 4.0e-12 6.7 5.8 7.4e-09 0.81 0.01 0.99 FALSE
10 GTEx Thyroid WSB1 0.07 0.00 enet 14 0.00 3.2e-01 6.3 -5.3 9.2e-08 -0.70 0.02 0.79 FALSE
11 NTR Blood WSB1 0.06 0.01 lasso 5 0.03 6.1e-11 -1.9 -5.5 4.7e-08 -0.67 0.14 0.86 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma WSB1 0.05 0.05 enet 4 0.04 8.9e-05 6.5 6.2 5.7e-10 0.81 0.03 0.96 FALSE