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chr3:52,242,902-53,860,103

Best TWAS P=1.45e-09 · Best GWAS P=4.09e-08 conditioned to 0.639

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
29	The Cancer Genome Atlas	Glioblastoma Multiforme	RFT1	0.20	0.14	enet	11	0.09	8.8e-04	5.5	6.0	1.4e-09	0.93	0.01	0.96	TRUE
18	GTEx	Prostate	RFT1	0.39	0.18	enet	17	0.24	1.1e-06	5.5	5.9	4.6e-09	0.87	0.01	0.99	FALSE
13	GTEx	Esophagus Mucosa	RFT1	0.24	0.24	enet	10	0.22	6.2e-15	5.4	5.8	7.1e-09	0.98	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RFT1	0.41	0.17	enet	12	0.16	2.4e-07	5.5	5.7	9.7e-09	0.93	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RFT1	0.23	0.09	blup	45	0.08	3.8e-04	4.9	5.7	1.1e-08	0.92	0.01	0.96	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	RFT1	0.22	0.28	enet	13	0.31	2.5e-36	5.5	5.7	1.4e-08	0.94	0.01	0.99	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RFT1	0.15	0.21	lasso	8	0.22	1.4e-24	5.4	5.7	1.5e-08	0.98	0.01	0.99	FALSE
11	GTEx	Colon Transverse	RFT1	0.30	0.27	enet	16	0.24	8.0e-12	5.5	5.7	1.6e-08	0.97	0.01	0.99	FALSE
16	GTEx	Nerve Tibial	RFT1	0.35	0.31	enet	17	0.27	1.9e-19	5.5	5.6	2.4e-08	0.99	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RFT1	0.14	0.10	lasso	4	0.12	8.4e-14	5.5	5.6	2.5e-08	0.93	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RFT1	0.21	0.22	lasso	3	0.22	5.7e-26	5.4	5.6	2.8e-08	0.99	0.01	0.99	FALSE
9	GTEx	Cells Transformed fibroblasts	RFT1	0.22	0.21	enet	16	0.22	2.8e-16	5.5	5.5	3.0e-08	0.97	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	RFT1	0.16	0.15	enet	12	0.10	1.0e-05	5.4	5.5	3.1e-08	0.97	0.01	0.99	FALSE
20	GTEx	Small Intestine Terminal Ileum	RFT1	0.20	0.20	enet	19	0.11	2.2e-03	5.5	5.5	3.7e-08	0.98	0.01	0.95	FALSE
6	GTEx	Artery Coronary	RFT1	0.38	0.33	lasso	5	0.34	2.6e-12	5.5	5.5	3.9e-08	1.00	0.01	0.99	FALSE
25	METSIM	Adipose	RFT1	0.13	0.19	lasso	7	0.18	7.8e-27	5.5	5.5	4.1e-08	1.00	0.01	0.99	FALSE
19	GTEx	Skin Sun Exposed Lower leg	RFT1	0.18	0.16	enet	7	0.13	1.1e-10	5.4	5.5	4.5e-08	1.00	0.01	0.99	FALSE
21	GTEx	Spleen	RFT1	0.23	0.22	enet	7	0.13	3.6e-04	5.4	5.5	4.5e-08	1.00	0.01	0.97	FALSE
4	GTEx	Adrenal Gland	RFT1	0.15	0.02	enet	11	0.03	4.0e-02	5.4	5.5	4.6e-08	0.94	0.02	0.92	FALSE
27	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RFT1	0.14	0.08	enet	12	0.15	5.5e-08	3.6	5.5	4.7e-08	0.83	0.02	0.98	FALSE
15	GTEx	Muscle Skeletal	RFT1	0.17	0.16	enet	17	0.15	3.0e-14	5.4	5.5	4.9e-08	0.96	0.01	0.99	FALSE
23	GTEx	Testis	RFT1	0.20	0.12	enet	8	0.10	2.9e-05	5.5	5.4	5.5e-08	0.98	0.01	0.99	FALSE
34	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFT1	0.21	0.10	lasso	6	0.23	1.9e-15	3.5	5.4	5.9e-08	0.81	0.02	0.98	FALSE
8	GTEx	Breast Mammary Tissue (Male)	RFT1	0.23	0.12	enet	8	0.13	5.5e-04	5.4	5.4	6.3e-08	0.99	0.01	0.88	FALSE
14	GTEx	Lung	RFT1	0.24	0.23	enet	12	0.23	2.7e-17	5.4	5.4	6.4e-08	0.98	0.01	0.99	FALSE
10	GTEx	Colon Sigmoid	RFT1	0.55	0.45	enet	15	0.43	1.0e-16	5.4	5.4	7.4e-08	0.99	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RFT1	0.24	0.12	lasso	5	0.20	1.3e-11	3.5	5.4	7.9e-08	0.80	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFT1	0.10	0.08	enet	11	0.15	2.3e-29	3.5	5.3	1.0e-07	0.82	0.01	0.98	FALSE
5	GTEx	Artery Aorta	RFT1	0.40	0.32	lasso	13	0.31	8.1e-18	5.5	-5.3	1.3e-07	-1.00	0.01	0.99	FALSE
17	GTEx	Nerve Tibial	SFMBT1	0.21	0.10	enet	11	0.07	1.4e-05	5.5	-5.3	1.3e-07	-1.00	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Stomach Adenocarcinoma	RFT1	0.13	0.05	blup	45	0.10	6.9e-08	3.6	5.3	1.3e-07	0.74	0.02	0.98	FALSE
22	GTEx	Stomach	RFT1	0.23	0.03	enet	19	0.06	6.3e-04	5.5	5.3	1.4e-07	0.76	0.01	0.98	FALSE
24	GTEx	Thyroid	RFT1	0.36	0.33	enet	17	0.35	2.4e-27	5.4	5.3	1.4e-07	0.98	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	RFT1	0.21	0.19	enet	24	0.17	3.7e-14	5.5	5.2	2.0e-07	0.98	0.01	0.99	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	RFT1	0.25	0.30	lasso	4	0.29	3.8e-28	5.5	5.2	2.0e-07	0.99	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	RFT1	0.10	0.05	enet	12	0.05	1.0e-03	3.5	5.2	2.5e-07	0.73	0.03	0.72	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	RFT1	0.43	0.37	enet	18	0.34	7.0e-13	5.4	5.1	2.9e-07	0.97	0.01	0.99	FALSE
7	GTEx	Artery Tibial	RFT1	0.40	0.38	enet	22	0.40	8.2e-33	5.5	5.1	3.0e-07	0.99	0.01	0.99	FALSE