[Hub]/) : Traits : Birth weight :

chr3:52,242,902-53,860,103

Best TWAS P=1.45e-09 · Best GWAS P=4.09e-08 conditioned to 0.639

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RFT1 0.21 0.22 lasso 3 0.22 5.7e-26 5.4 5.6 2.8e-08 0.99 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous RFT1 0.21 0.19 enet 24 0.17 3.7e-14 5.5 5.2 2.0e-07 0.98 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum RFT1 0.16 0.15 enet 12 0.10 1.0e-05 5.4 5.5 3.1e-08 0.97 0.01 0.99 FALSE
4 GTEx Adrenal Gland RFT1 0.15 0.02 enet 11 0.03 4.0e-02 5.4 5.5 4.6e-08 0.94 0.02 0.92 FALSE
5 GTEx Artery Aorta RFT1 0.40 0.32 lasso 13 0.31 8.1e-18 5.5 -5.3 1.3e-07 -1.00 0.01 0.99 FALSE
6 GTEx Artery Coronary RFT1 0.38 0.33 lasso 5 0.34 2.6e-12 5.5 5.5 3.9e-08 1.00 0.01 0.99 FALSE
7 GTEx Artery Tibial RFT1 0.40 0.38 enet 22 0.40 8.2e-33 5.5 5.1 3.0e-07 0.99 0.01 0.99 FALSE
8 GTEx Breast Mammary Tissue (Male) RFT1 0.23 0.12 enet 8 0.13 5.5e-04 5.4 5.4 6.3e-08 0.99 0.01 0.88 FALSE
9 GTEx Cells Transformed fibroblasts RFT1 0.22 0.21 enet 16 0.22 2.8e-16 5.5 5.5 3.0e-08 0.97 0.01 0.99 FALSE
10 GTEx Colon Sigmoid RFT1 0.55 0.45 enet 15 0.43 1.0e-16 5.4 5.4 7.4e-08 0.99 0.01 0.99 FALSE
11 GTEx Colon Transverse RFT1 0.30 0.27 enet 16 0.24 8.0e-12 5.5 5.7 1.6e-08 0.97 0.01 0.99 FALSE
12 GTEx Esophagus Gastroesophageal Junction RFT1 0.43 0.37 enet 18 0.34 7.0e-13 5.4 5.1 2.9e-07 0.97 0.01 0.99 FALSE
13 GTEx Esophagus Mucosa RFT1 0.24 0.24 enet 10 0.22 6.2e-15 5.4 5.8 7.1e-09 0.98 0.01 0.99 FALSE
14 GTEx Lung RFT1 0.24 0.23 enet 12 0.23 2.7e-17 5.4 5.4 6.4e-08 0.98 0.01 0.99 FALSE
15 GTEx Muscle Skeletal RFT1 0.17 0.16 enet 17 0.15 3.0e-14 5.4 5.5 4.9e-08 0.96 0.01 0.99 FALSE
16 GTEx Nerve Tibial RFT1 0.35 0.31 enet 17 0.27 1.9e-19 5.5 5.6 2.4e-08 0.99 0.01 0.99 FALSE
17 GTEx Nerve Tibial SFMBT1 0.21 0.10 enet 11 0.07 1.4e-05 5.5 -5.3 1.3e-07 -1.00 0.01 0.99 FALSE
18 GTEx Prostate RFT1 0.39 0.18 enet 17 0.24 1.1e-06 5.5 5.9 4.6e-09 0.87 0.01 0.99 FALSE
19 GTEx Skin Sun Exposed Lower leg RFT1 0.18 0.16 enet 7 0.13 1.1e-10 5.4 5.5 4.5e-08 1.00 0.01 0.99 FALSE
20 GTEx Small Intestine Terminal Ileum RFT1 0.20 0.20 enet 19 0.11 2.2e-03 5.5 5.5 3.7e-08 0.98 0.01 0.95 FALSE
21 GTEx Spleen RFT1 0.23 0.22 enet 7 0.13 3.6e-04 5.4 5.5 4.5e-08 1.00 0.01 0.97 FALSE
22 GTEx Stomach RFT1 0.23 0.03 enet 19 0.06 6.3e-04 5.5 5.3 1.4e-07 0.76 0.01 0.98 FALSE
23 GTEx Testis RFT1 0.20 0.12 enet 8 0.10 2.9e-05 5.5 5.4 5.5e-08 0.98 0.01 0.99 FALSE
24 GTEx Thyroid RFT1 0.36 0.33 enet 17 0.35 2.4e-27 5.4 5.3 1.4e-07 0.98 0.01 0.99 FALSE
25 METSIM Adipose RFT1 0.13 0.19 lasso 7 0.18 7.8e-27 5.5 5.5 4.1e-08 1.00 0.01 0.99 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma RFT1 0.10 0.08 enet 11 0.15 2.3e-29 3.5 5.3 1.0e-07 0.82 0.01 0.98 FALSE
27 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RFT1 0.14 0.08 enet 12 0.15 5.5e-08 3.6 5.5 4.7e-08 0.83 0.02 0.98 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma RFT1 0.10 0.05 enet 12 0.05 1.0e-03 3.5 5.2 2.5e-07 0.73 0.03 0.72 FALSE
29 The Cancer Genome Atlas Glioblastoma Multiforme RFT1 0.20 0.14 enet 11 0.09 8.8e-04 5.5 6.0 1.4e-09 0.93 0.01 0.96 TRUE
30 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RFT1 0.14 0.10 lasso 4 0.12 8.4e-14 5.5 5.6 2.5e-08 0.93 0.01 0.99 FALSE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RFT1 0.15 0.21 lasso 8 0.22 1.4e-24 5.4 5.7 1.5e-08 0.98 0.01 0.99 FALSE
32 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RFT1 0.24 0.12 lasso 5 0.20 1.3e-11 3.5 5.4 7.9e-08 0.80 0.02 0.98 FALSE
33 The Cancer Genome Atlas Brain Lower Grade Glioma RFT1 0.22 0.28 enet 13 0.31 2.5e-36 5.5 5.7 1.4e-08 0.94 0.01 0.99 FALSE
34 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFT1 0.21 0.10 lasso 6 0.23 1.9e-15 3.5 5.4 5.9e-08 0.81 0.02 0.98 FALSE
35 The Cancer Genome Atlas Pancreatic Adenocarcinoma RFT1 0.41 0.17 enet 12 0.16 2.4e-07 5.5 5.7 9.7e-09 0.93 0.01 0.99 FALSE
36 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RFT1 0.23 0.09 blup 45 0.08 3.8e-04 4.9 5.7 1.1e-08 0.92 0.01 0.96 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma RFT1 0.13 0.05 blup 45 0.10 6.9e-08 3.6 5.3 1.3e-07 0.74 0.02 0.98 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma RFT1 0.25 0.30 lasso 4 0.29 3.8e-28 5.5 5.2 2.0e-07 0.99 0.01 0.99 FALSE