Best TWAS P=1.56e-18 · Best GWAS P=3.28e-24 conditioned to 2.51e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP11-797D24.4 | 0.17 | 0.03 | lasso | 3 | 0.06 | 2.6e-04 | -6.0 | 5.8 | 5.8e-09 | 0.28 | 0.25 | 0.03 | FALSE |
| 2 | GTEx | Artery Tibial | ADCY5 | 0.17 | 0.03 | lasso | 6 | 0.04 | 8.9e-04 | -7.6 | 7.6 | 2.8e-14 | 0.36 | 0.91 | 0.07 | FALSE |
| 3 | GTEx | Artery Tibial | RP11-797D24.4 | 0.20 | 0.03 | lasso | 5 | 0.05 | 9.4e-05 | -7.6 | 7.5 | 5.0e-14 | 0.37 | 0.92 | 0.06 | FALSE |
| 4 | GTEx | Lung | RP11-797D24.4 | 0.08 | 0.01 | enet | 10 | 0.03 | 4.1e-03 | -7.6 | 8.8 | 1.6e-18 | 0.50 | 0.06 | 0.86 | TRUE |