Best TWAS P=8.07e-08 · Best GWAS P=2.93e-07 conditioned to 0.87
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | TRAPPC3 | 0.10 | 0.08 | lasso | 3 | 0.08 | 7.2e-07 | -4.9 | 5.2 | 2.1e-07 | -0.86 | 0.01 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | TRAPPC3 | 0.07 | 0.02 | blup | 38 | 0.03 | 5.7e-03 | -5.1 | -5.4 | 8.1e-08 | 0.94 | 0.01 | 0.88 | TRUE |