Best TWAS P=2.07e-10 · Best GWAS P=1.05e-17 conditioned to 1.11e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC22A3 | 0.10 | 0.02 | blup | 582 | 0.05 | 4.4e-07 | 4.4 | 6.1 | 8.7e-10 | 0.09 | 0.09 | 0.91 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC22A3 | 0.14 | 0.20 | lasso | 10 | 0.19 | 2.4e-24 | 4.4 | 5.1 | 3.1e-07 | 0.04 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC22A1 | 0.04 | 0.01 | enet | 17 | 0.01 | 5.2e-04 | 4.6 | -6.4 | 2.1e-10 | -0.59 | 0.01 | 0.94 | TRUE |