Best TWAS P=1.13e-09 · Best GWAS P=4.38e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | CAMK1D | 0.28 | 0.24 | enet | 25 | 0.24 | 2.3e-18 | 6.2 | 6.1 | 1.1e-09 | 0.96 | 0.00 | 1.00 | TRUE |
2 | GTEx | Whole Blood | CAMK1D | 0.14 | 0.01 | enet | 26 | 0.04 | 2.5e-04 | 6.2 | 5.5 | 5.1e-08 | 0.81 | 0.00 | 1.00 | FALSE |
3 | NTR | Blood | CAMK1D | 0.10 | 0.09 | bslmm | 900 | 0.08 | 4.4e-25 | 6.2 | 5.9 | 2.8e-09 | 0.97 | 0.00 | 1.00 | FALSE |
4 | YFS | Blood | CAMK1D | 0.27 | 0.23 | bslmm | 875 | 0.26 | 7.7e-86 | 6.2 | 5.7 | 9.3e-09 | 0.93 | 0.00 | 1.00 | FALSE |
5 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | 6.2 | 5.2 | 2.2e-07 | 0.90 | 0.00 | 1.00 | FALSE |
6 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC123 | 0.26 | 0.07 | lasso | 4 | 0.07 | 1.4e-03 | 5.4 | -5.5 | 2.9e-08 | -0.85 | 0.01 | 0.92 | FALSE |