Best TWAS P=1.18e-08 · Best GWAS P=2.37e-07 conditioned to 0.155
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | NFATC3 | 0.04 | 0.01 | lasso | 4 | 0.01 | 0.0405 | -4.8 | 5.2 | 2.2e-07 | -0.77 | 0.02 | 0.89 | FALSE |
2 | METSIM | Adipose | PLA2G15 | 0.03 | 0.01 | blup | 287 | 0.01 | 0.0048 | -4.6 | -5.7 | 1.2e-08 | 0.74 | 0.01 | 0.93 | TRUE |