Best TWAS P=5.17e-08 · Best GWAS P=1.86e-07 conditioned to 0.111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | ACO2 | 0.03 | 0.01 | blup | 41 | 0.04 | 0.0039 | 5.2 | -5.1 | 2.8e-07 | -0.71 | 0.01 | 0.56 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PHF5A | 0.03 | 0.00 | blup | 30 | 0.01 | 0.0286 | -4.3 | -5.4 | 5.2e-08 | -0.77 | 0.01 | 0.53 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TOB2 | 0.03 | 0.00 | blup | 28 | 0.02 | 0.0034 | -4.4 | -5.4 | 5.8e-08 | -0.68 | 0.01 | 0.24 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | POLR3H | 0.10 | 0.02 | blup | 23 | 0.06 | 0.0034 | -4.3 | 5.2 | 2.4e-07 | 0.72 | 0.02 | 0.44 | FALSE |