43 significantly associated models · 27 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 43476957 | 45088053 | 1 | 1 | 1.5e-07 | 5.8e-11 | 2.7e-05 | 59 | ST3GAL3 |
2 | 3 | 84767271 | 86367480 | 1 | 1 | 6.1e-08 | 5.0e-06 | 3.9e-03 | 60 | CADM2 |
3 | 8 | 27099879 | 27720371 | 2 | 2 | 1.0e-09 | 5.1e-10 | 4.6e-02 | 90 | CLU EPHX2 |
4 | 9 | 126927285 | 129422783 | 8 | 2 | 8.5e-10 | 4.5e-08 | 7.8e-01 | 100 | MAPKAP1 PRPS1P2 |
5 | 9 | 135521303 | 136922700 | 1 | 1 | 1.6e-07 | 2.4e-19 | 1.5e-15 | 21 | SURF1 |
6 | 10 | 103550604 | 105647095 | 6 | 2 | 5.2e-09 | 3.6e-08 | 6.0e-02 | 88 | ACTR1A NT5C2 |
7 | 11 | 16709350 | 18106069 | 1 | 1 | 2.2e-07 | 3.8e-07 | 4.9e-02 | 85 | KCNJ11 |
8 | 15 | 46780520 | 48764942 | 1 | 1 | 8.9e-08 | 1.4e-08 | 3.4e-03 | 73 | SEMA6D |
9 | 17 | 78843139 | 79380547 | 1 | 1 | 1.5e-07 | 4.2e-07 | 1.0e+00 | 100 | AATK |
10 | 22 | 41604557 | 42180584 | 4 | 1 | 5.2e-08 | 1.9e-07 | 1.1e-01 | 91 | PHF5A |
11 | 22 | 42255525 | 43674249 | 1 | 1 | 1.3e-07 | 1.3e-05 | 8.0e-01 | 100 | RRP7B |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Adipose Subcutaneous | 1 | 0.029 | 1.7 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.7 |
GTEx | Brain Cortex | 2 | 0.193 | 1.7 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.7 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.7 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.7 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.7 |
GTEx | Esophagus Muscularis | 0 | 0.000 | 1.7 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.7 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.7 |
GTEx | Pancreas | 0 | 0.000 | 1.7 |
GTEx | Prostate | 0 | 0.000 | 1.7 |
GTEx | Stomach | 0 | 0.000 | 1.7 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 0 | 0.000 | 1.7 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.7 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.7 |
GTEx | Adipose Visceral Omentum | 1 | 0.049 | 1.6 |
GTEx | Artery Aorta | 0 | 0.000 | 1.6 |
GTEx | Artery Coronary | 1 | 0.085 | 1.6 |
GTEx | Artery Tibial | 2 | 0.053 | 1.6 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.6 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.6 |
GTEx | Brain Cerebellum | 2 | 0.101 | 1.6 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.6 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.6 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.6 |
GTEx | Cells Transformed fibroblasts | 2 | 0.048 | 1.6 |
GTEx | Colon Transverse | 0 | 0.000 | 1.6 |
GTEx | Esophagus Mucosa | 0 | 0.000 | 1.6 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.6 |
GTEx | Liver | 1 | 0.139 | 1.6 |
GTEx | Lung | 0 | 0.000 | 1.6 |
GTEx | Nerve Tibial | 1 | 0.023 | 1.6 |
GTEx | Pituitary | 0 | 0.000 | 1.6 |
GTEx | Skin Not Sun Exposed Suprapubic | 1 | 0.041 | 1.6 |
GTEx | Skin Sun Exposed Lower leg | 2 | 0.055 | 1.6 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.6 |
GTEx | Spleen | 1 | 0.071 | 1.6 |
GTEx | Testis | 0 | 0.000 | 1.6 |
GTEx | Thyroid | 1 | 0.025 | 1.6 |
GTEx | Uterus | 0 | 0.000 | 1.6 |
GTEx | Whole Blood | 1 | 0.050 | 1.6 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 2 | 0.037 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 1 | 0.060 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.098 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 2 | 0.098 | 1.6 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 2 | 0.046 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.6 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 1 | 0.075 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 2 | 0.156 | 1.6 |
The Cancer Genome Atlas | Thyroid Carcinoma | 2 | 0.039 | 1.6 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.5 |
GTEx | Ovary | 0 | 0.000 | 1.5 |
GTEx | Vagina | 0 | 0.000 | 1.5 |
METSIM | Adipose | 0 | 0.000 | 1.5 |
NTR | Blood | 1 | 0.042 | 1.5 |
YFS | Blood | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 2 | 0.045 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 0 | 0.000 | 1.5 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.4 |