[Hub]/) : Traits : Neuroticism score :

chr9:95,502,571-96,913,764

Best TWAS P=2.35e-09 · Best GWAS P=2.89e-09 conditioned to 1.05e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-165J3.6 0.26 0.13 lasso 6 0.13 4.2e-07 3.8 5.2 2.4e-07 -0.30 0.35 0.64 FALSE
2 GTEx Artery Aorta RP11-165J3.6 0.23 0.22 enet 10 0.22 2.3e-12 5.8 5.8 8.2e-09 -0.26 0.02 0.98 FALSE
3 GTEx Artery Tibial RP11-165J3.6 0.22 0.20 lasso 2 0.19 4.9e-15 5.8 5.8 5.6e-09 -0.26 0.01 0.99 FALSE
4 GTEx Brain Caudate basal ganglia RP11-165J3.6 0.47 0.33 lasso 7 0.31 1.0e-09 5.8 5.2 2.5e-07 -0.14 0.01 0.98 FALSE
5 GTEx Brain Cerebellum RP11-165J3.6 0.44 0.31 lasso 7 0.28 5.0e-09 5.8 5.5 3.5e-08 -0.19 0.01 0.99 FALSE
6 GTEx Brain Frontal Cortex BA9 RP11-165J3.6 0.41 0.14 lasso 6 0.20 6.1e-06 5.8 5.4 6.0e-08 -0.17 0.02 0.98 FALSE
7 GTEx Breast Mammary Tissue (Female) RP11-165J3.6 0.21 0.02 lasso 3 0.00 2.3e-01 5.9 5.8 6.3e-09 -0.27 0.03 0.62 FALSE
8 GTEx Colon Transverse RP11-165J3.6 0.37 0.20 lasso 4 0.18 3.6e-09 5.8 5.6 2.4e-08 -0.19 0.01 0.99 FALSE
9 GTEx Esophagus Gastroesophageal Junction RP11-165J3.6 0.34 0.26 lasso 8 0.27 3.0e-10 5.8 5.9 3.7e-09 -0.27 0.01 0.99 FALSE
10 GTEx Heart Atrial Appendage RP11-165J3.6 0.38 0.21 lasso 7 0.25 8.7e-12 5.6 5.7 1.3e-08 -0.26 0.06 0.93 FALSE
11 GTEx Heart Left Ventricle RP11-165J3.6 0.13 0.06 lasso 5 0.05 1.9e-03 5.8 5.2 2.1e-07 -0.17 0.03 0.92 FALSE
12 GTEx Lung RP11-165J3.6 0.25 0.16 lasso 7 0.17 4.1e-13 5.8 6.0 2.3e-09 -0.29 0.02 0.98 TRUE
13 GTEx Pituitary RP11-165J3.6 0.49 0.22 lasso 8 0.29 6.9e-08 5.9 5.5 4.9e-08 -0.17 0.02 0.96 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic RP11-165J3.6 0.27 0.14 lasso 7 0.19 1.4e-10 5.5 5.4 5.2e-08 -0.20 0.04 0.96 FALSE
15 GTEx Skin Sun Exposed Lower leg RP11-165J3.6 0.32 0.27 lasso 5 0.35 6.8e-30 5.9 5.8 8.0e-09 -0.24 0.02 0.98 FALSE
16 GTEx Thyroid RP11-165J3.6 0.35 0.27 lasso 3 0.29 1.2e-22 5.8 5.9 3.8e-09 -0.30 0.02 0.98 FALSE
17 YFS Blood FAM120AOS 0.03 0.01 bslmm 488 0.02 5.3e-06 5.9 -5.5 4.0e-08 0.61 0.02 0.97 FALSE