Best TWAS P=3.83e-09 · Best GWAS P=9.72e-10 conditioned to 0.0649
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | MMAB | 0.07 | 0.06 | enet | 9 | 0.05 | 7.3e-05 | 5.0 | -5.5 | 3.4e-08 | -0.91 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Colon Transverse | KCTD10 | 0.22 | 0.12 | lasso | 11 | 0.13 | 1.1e-06 | -4.7 | -5.2 | 2.0e-07 | -0.72 | 0.38 | 0.61 | FALSE |
| 3 | GTEx | Nerve Tibial | USP30 | 0.07 | 0.01 | lasso | 4 | 0.01 | 1.1e-01 | 4.3 | 5.3 | 1.5e-07 | 0.81 | 0.04 | 0.79 | FALSE |
| 4 | GTEx | Thyroid | KCTD10 | 0.06 | 0.02 | enet | 12 | 0.02 | 9.2e-03 | 6.1 | -5.3 | 1.4e-07 | -0.85 | 0.01 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MMAB | 0.03 | 0.02 | blup | 57 | 0.02 | 2.2e-03 | 5.4 | -5.7 | 1.3e-08 | -0.74 | 0.01 | 0.90 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | KCTD10 | 0.15 | 0.08 | lasso | 6 | 0.08 | 2.1e-08 | 5.6 | -5.9 | 3.8e-09 | -0.90 | 0.04 | 0.96 | TRUE |