Best TWAS P=1.43e-07 · Best GWAS P=5.57e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | DENND2D | 0.31 | 0.16 | lasso | 6 | 0.19 | 4.9e-14 | 5.4 | 5.1 | 2.6e-07 | 0.86 | 0 | 1 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | DENND2D | 0.13 | 0.06 | lasso | 3 | 0.06 | 3.9e-06 | 5.4 | -5.3 | 1.4e-07 | -0.99 | 0 | 1 | TRUE |