TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr1:111,034,818-112,443,281
Best TWAS P=1.43e-07 · Best GWAS P=5.57e-08 conditioned to 1
111M
111.2M
111.4M
111.6M
111.8M
112M
112.2M
112.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
DENND2D
0.13
0.06
lasso
3
0.06
3.9e-06
5.4
-5.3
1.4e-07
-0.99
0
1
TRUE
1
GTEx
Cells Transformed fibroblasts
DENND2D
0.31
0.16
lasso
6
0.19
4.9e-14
5.4
5.1
2.6e-07
0.86
0
1
FALSE