[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr1:77,655,651-79,300,939

Best TWAS P=5.84e-09 · Best GWAS P=1.08e-08 conditioned to 0.105

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes NEXN 0.23 0.10 lasso 3 0.08 1.4e-03 -5.4 -5.6 2.4e-08 0.85 0.02 0.88 FALSE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 -5.3 5.8 8.8e-09 -0.85 0.03 0.97 FALSE
3 GTEx Nerve Tibial DNAJB4 0.08 0.07 lasso 3 0.07 1.3e-05 -5.5 -5.4 5.7e-08 0.78 0.02 0.97 FALSE
4 GTEx Pancreas GIPC2 0.41 0.13 enet 29 0.14 1.1e-06 -5.2 5.4 6.0e-08 -0.61 0.02 0.97 FALSE
5 GTEx Skin Sun Exposed Lower leg DNAJB4 0.07 0.05 lasso 5 0.05 6.5e-05 -5.5 -5.7 1.4e-08 0.75 0.02 0.96 FALSE
6 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 -4.5 5.2 2.0e-07 -0.73 0.07 0.92 FALSE
7 ROSMAP Brain Pre-frontal Cortex DNAJB4 0.08 0.09 lasso 2 0.09 1.3e-11 -5.3 -5.3 1.2e-07 0.79 0.04 0.95 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJB4 0.05 0.03 lasso 3 0.02 3.3e-03 -5.2 -5.7 8.9e-09 0.93 0.00 0.99 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DNAJB4 0.08 0.07 lasso 1 0.06 9.3e-08 -5.2 -5.2 1.7e-07 0.79 0.03 0.97 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma GIPC2 0.10 0.11 blup 64 0.13 1.1e-13 -5.7 5.8 5.8e-09 -0.82 0.01 0.99 TRUE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors DNAJB4 0.24 0.14 lasso 1 0.11 1.1e-04 -5.2 -5.2 1.7e-07 0.79 0.01 0.93 FALSE