Best TWAS P=1.15e-09 · Best GWAS P=3.27e-11 conditioned to 0.00276
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | ILF3-AS1 | 0.11 | 0.00 | lasso | 4 | 0.00 | 2.5e-01 | 6.2 | -5.2 | 1.5e-07 | -0.42 | 0.04 | 0.70 | FALSE |
| 2 | GTEx | Nerve Tibial | ILF3-AS1 | 0.14 | 0.04 | lasso | 3 | 0.08 | 3.8e-06 | 6.3 | -5.7 | 1.4e-08 | -0.46 | 0.03 | 0.94 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | SMARCA4 | 0.15 | 0.10 | enet | 25 | 0.15 | 1.4e-12 | 3.5 | -5.2 | 2.2e-07 | -0.70 | 0.69 | 0.31 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC147727 | 0.07 | 0.02 | lasso | 2 | 0.02 | 5.4e-03 | 6.2 | -6.1 | 1.1e-09 | -0.79 | 0.01 | 0.84 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC44A2 | 0.32 | 0.22 | enet | 14 | 0.25 | 3.8e-24 | 6.1 | 5.5 | 4.6e-08 | 0.74 | 0.03 | 0.97 | FALSE |