Hub : Genes

SLC44A2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.1260	0.0480	2.2e-03	-0.001	NA	0.015	NA	0.021	3.8e-01	NA	3.1e-02	NA	1.4e-02
2	GTEx	Muscle Skeletal	0.1925	0.0431	1.0e-13	0.182	NA	0.171	NA	0.187	1.6e-17	NA	1.5e-16	NA	5.1e-18
3	GTEx	Skin Sun Exposed Lower leg	0.2010	0.0540	1.5e-08	0.211	NA	0.197	NA	0.214	2.6e-17	NA	3.7e-16	NA	1.5e-17
4	GTEx	Thyroid	0.1380	0.0540	4.6e-03	0.076	NA	0.038	NA	0.054	1.8e-06	NA	6.6e-04	NA	5.9e-05
5	GTEx	Whole Blood	0.1130	0.0370	2.3e-04	0.010	NA	0.020	NA	0.009	3.5e-02	NA	5.2e-03	NA	4.1e-02
6	ROSMAP	Brain Pre-frontal Cortex	0.0841	0.0314	1.1e-03	-0.002	0.010	-0.002	0.010	-0.001	6.1e-01	1.4e-02	7.6e-01	1.6e-02	4.5e-01
7	YFS	Blood	0.1289	0.0263	0.0e+00	0.067	0.087	0.101	0.102	0.101	5.0e-21	4.0e-27	2.9e-31	1.7e-31	3.4e-31
8	TCGA	Liver Hepatocellular Carcinoma	0.0940	0.0520	8.4e-03	-0.005	0.033	0.018	NA	0.011	7.4e-01	1.1e-02	4.6e-02	NA	9.5e-02
9	TCGA	Thyroid Carcinoma	0.3230	0.0760	0.0e+00	0.219	0.225	0.249	NA	0.240	4.7e-21	1.3e-21	3.8e-24	NA	3.4e-23

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	4.2	6.7	22.5	2.0	-3.7	1.2	0.7	1.8	-3.1	1.4	1.7	-4.7
Bipolar Disorder or Schizophrenia	0.9	2.2	5.6	2.4	-2.2	0.6	1.0	-0.5	-0.9	0.9	1.5	-1.9
Depressed Affect (Nagel 2018)	0.5	1.1	2.5	-0.3	1.3	-0.8	0.5	-1.5	-0.2	-0.9	-1.6	1.3
Depression (Nagel 2018)	0.2	0.3	0.8	0.3	0.6	0.4	0.2	-0.7	0.2	0.1	-0.9	0.8
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.6	1.5	0.2	1.5	1.6	0.5	-1.9	0.7	-1.1	0.6
Neuroticism (Nagel 2018)	0.7	1.7	6.6	1.4	0.4	1.2	2.6	0.5	-0.8	0.6	-1.8	0.9
Schizophrenia (2018)	0.6	1.2	4.0	1.5	0.1	-0.3	0.8	-2.0	1.4	-0.0	0.5	1.3
Schizophrenia vs Biploar Disorder	2.6	3.4	14.9	-0.9	2.4	-1.3	0.2	-1.4	1.7	-0.9	-1.2	3.9
Worry (Nagel 2018)	1.2	2.6	8.2	1.6	-0.1	1.8	2.9	1.1	-1.9	1.1	-1.7	0.4
Alzheimer’s Disease (in mother)	2.3	2.6	4.9	1.2	-1.8	2.1	0.5	2.2	-0.5	2.1	1.2	-1.8
Alzheimer’s Disease (in father)	0.8	0.9	2.8	-0.2	-0.2	-0.8	-1.6	0.2	-0.6	-1.2	0.3	-1.7
Alzheimer’s Disease (including proxy)	1.6	2.3	6.5	1.2	-1.5	1.5	-0.0	2.5	-0.6	1.1	1.4	-2.2
Crohns Disease (2017)	0.8	1.7	6.2	1.0	-0.5	1.9	-0.1	0.8	2.5	1.3	1.1	-0.8
Irritable Bowel Disease (IBD)	1.4	3.3	7.4	1.0	-1.1	2.6	-0.0	1.0	2.6	2.7	1.9	-1.5
Ulcerative Colitis (UC)	1.2	2.2	8.2	0.6	-1.1	1.6	0.2	0.9	1.4	2.9	1.6	-1.4
Major Depression (MDD)	1.8	2.2	14.8	0.5	-0.3	0.1	0.0	0.0	-3.9	-0.2	-2.1	-0.8
Reaction Time	3.3	6.2	16.0	1.7	-4.0	2.4	0.8	2.5	-0.7	2.9	2.7	-2.9
Verbal and Numeric Reasoning (VNR)	0.5	1.3	3.3	1.3	0.2	0.3	1.4	0.8	-1.8	-0.1	-1.4	1.2
Breast Cancer	0.6	1.3	3.2	1.3	-1.2	1.7	1.8	1.3	-0.2	0.3	-0.5	-0.9
Ovarian Cancer	1.6	2.2	3.9	0.5	-1.8	1.8	-0.4	2.0	0.6	1.2	1.7	-2.0
Prostate Cancer	0.1	0.2	0.5	0.2	0.2	0.7	0.7	-0.1	-0.6	0.1	-0.5	0.1
Age at First Birth	0.3	0.5	1.3	-0.6	1.1	-0.6	0.2	0.5	-0.4	-0.2	-1.0	0.9
Bipolar Disorder (2011)	0.7	0.7	4.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	-2.1
Body Mass Index (BMI) (2010)	1.5	2.1	7.7	0.9	-0.3	1.2	1.3	0.9	2.8	1.5	0.5	1.9
Coronary Artery Disease (CAD)	2.7	3.2	12.5	1.6	-3.5	0.5	1.1	1.5	-0.7	1.6	1.9	-1.9
Crohns Disease (2012)	0.7	1.1	3.4	1.0	-0.3	1.8	-0.3	0.9	1.5	1.2	0.7	-0.6
Mean Putamen Volume	0.7	0.8	4.0	-0.5	0.9	0.1	-0.3	-0.6	1.1	-0.2	0.1	2.0
Fasting Glucose	0.2	0.3	0.9	-0.2	-0.1	-0.6	-0.2	-0.4	-0.4	-0.9	-0.5	-0.9
HbA1C	0.3	0.3	1.3	0.3	0.1	0.7	-0.5	-0.1	1.1	-0.4	0.5	-0.4
HDL Cholesterol	2.8	4.6	9.5	-1.4	2.5	-3.1	-2.3	-2.8	-0.6	-2.9	-1.2	0.1
LDL Cholesterol	7.3	11.6	45.4	0.0	-6.7	-0.5	-1.6	1.4	-4.5	0.7	4.6	-3.5
Lupus	0.8	1.2	3.4	1.3	-0.6	0.9	1.8	1.3	0.8	1.0	-0.5	1.2
Neuroticism (2016)	0.3	0.5	1.5	1.2	-0.2	1.2	0.9	0.1	0.1	0.6	-0.4	0.1
Primary Biliary Cirrhosis	1.9	2.8	7.7	-1.7	-2.1	0.0	-2.2	1.1	0.7	0.2	2.8	-1.8
Rheumatoid Arthritis	2.0	2.8	11.0	-1.1	1.9	-0.9	0.8	0.4	2.4	0.2	-1.6	3.3
Schizophrenia (2014)	0.3	0.8	2.2	1.5	-0.8	0.4	0.2	-1.2	1.1	0.1	1.1	0.3
Triglycerides	0.5	0.9	4.2	-0.0	-0.6	2.0	-0.1	1.2	-0.8	0.4	-0.1	-0.9
Type 2 Diabetes (T2D) (2012)	1.1	1.3	4.0	0.4	0.0	0.6	1.1	-1.0	2.0	1.6	0.4	1.5
Ulcerative Colitis	0.5	0.8	2.9	0.3	-0.5	1.3	-0.0	0.2	0.9	1.7	0.8	-0.8
Blood Eosinophil Count	0.5	3.9	13.6	-0.1	3.7	-1.6	0.3	-1.6	1.1	-1.3	-2.3	2.8
Blood Platelet Count	1.5	17.7	39.3	-4.6	6.3	-4.4	-1.7	-2.2	5.6	-1.7	-1.3	6.0
Blood Red Count	0.4	4.3	17.3	-0.7	0.3	-1.5	-2.1	0.4	4.2	1.5	3.4	0.1
Blood White Count	1.4	10.2	43.6	1.4	-2.4	-0.0	-1.3	-0.1	6.6	3.3	5.3	-0.4
Heel T-Score	0.2	1.2	4.4	-0.9	0.3	-1.2	-1.1	0.7	1.0	-2.1	-1.2	0.1
BMI	0.5	2.7	8.1	-1.6	1.8	-0.2	-0.7	-1.0	2.8	-0.0	1.1	2.8
Height	4.1	78.2	234.1	-10.4	15.3	-5.5	-4.4	-9.1	-3.1	-6.3	-9.8	9.1
Waist Hip Ratio (WHR)	2.1	9.2	17.9	2.4	-3.8	2.7	1.9	3.2	-0.5	3.9	2.9	-4.2
Systolic Blood Pressure	0.5	2.5	11.5	0.0	-1.8	-1.1	-1.8	-0.4	0.3	-0.6	1.8	-3.4
Smoking Status	0.2	0.5	2.3	-0.9	-0.4	-0.9	-0.4	-0.1	-0.6	0.1	-0.0	-1.5
Allergy or Eczema	1.1	3.0	7.8	1.8	-0.2	0.1	2.4	1.6	-2.7	-0.2	-2.8	0.3
Cardiovascular Disease	0.6	2.0	4.4	-1.2	-1.6	-1.2	-2.1	-0.7	-0.7	-0.5	2.1	-1.6
Hypothyroidism (self reported)	0.5	1.1	6.1	-0.0	-1.4	1.2	-0.4	0.2	-0.3	0.2	0.6	-2.5
Respiratory disease	0.8	1.8	4.5	-1.3	2.0	-0.6	-0.2	-0.2	0.7	-1.1	-2.1	2.1
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.5	-0.6	0.1	0.6	-1.6	-0.7	1.9	-0.9	1.6	-1.2
Lung FEV1/FVC ratio	0.5	2.4	4.6	-1.4	0.5	-1.6	-1.6	-1.1	1.8	0.8	2.0	2.1
Lung FVC	0.6	2.9	17.2	0.7	1.7	-0.5	1.6	-0.7	0.8	0.1	-1.3	4.2
Neuroticism	0.4	1.1	3.3	0.5	0.9	1.6	1.5	0.4	-0.4	0.1	-1.8	0.5
Chronotype (morning person)	4.6	10.6	18.2	4.3	-4.2	3.6	2.6	3.1	0.3	3.2	2.6	-3.6
Hair Pigment	0.4	11.2	33.5	2.7	-5.8	1.7	1.3	1.5	-3.6	2.6	2.9	-5.1
Tanning	0.3	3.6	13.8	-0.2	-2.6	1.0	-1.5	-0.3	-2.6	-0.9	1.1	-3.7
Hand grip strength (left)	0.1	0.3	1.2	-0.8	0.0	0.2	-0.7	0.1	-0.0	0.5	0.7	-1.1
Number of treatments/medications taken	0.1	0.2	0.9	0.7	-0.4	0.3	-0.0	0.5	0.1	0.3	0.9	-0.2
Average weekly spirits intake	0.3	0.4	1.2	0.5	0.1	-0.8	0.8	1.1	-0.0	0.3	-0.2	0.6
Sensitivity / hurt feelings	0.3	0.4	1.0	0.3	-0.3	0.7	0.6	1.0	-0.7	0.4	-0.5	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.3	1.2	0.2	1.0	0.9	0.7	0.9	0.8	-0.4	1.1
Hearing difficulty/problems: Yes	1.8	2.8	8.5	-2.5	2.9	-2.1	-1.2	-0.8	-0.2	-0.9	-1.6	0.9
Relative age of first facial hair	0.3	0.6	1.9	0.4	1.0	-0.1	1.4	-0.4	-0.3	0.1	-1.2	0.4
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.9	-0.7	0.1	-0.3	-0.9	-0.3	2.0	0.5	1.0	1.1
Ever used hormone-replacement therapy (HRT)	3.1	3.9	11.9	3.4	-1.7	2.5	2.5	1.2	1.3	1.6	1.4	-0.3
Ever had hysterectomy (womb removed)	1.9	2.2	4.2	1.7	-2.0	1.4	0.3	1.4	0.5	1.5	1.5	-2.1
Systolic blood pressure, automated reading	0.7	2.1	4.9	-1.2	-0.4	-1.0	-2.2	-1.9	1.3	-0.2	2.2	-1.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	3.8	-0.4	0.2	0.0	-0.4	-0.6	2.0	-0.2	0.5	0.6
Angina	1.0	1.3	3.7	0.2	-1.7	0.7	-1.2	0.5	-0.5	0.0	1.6	-1.9
Medication for hormone replacement therapy	0.9	1.0	3.8	0.9	-0.3	0.9	1.1	-0.6	1.1	0.4	-0.2	1.9
Vitamin and mineral supplements	0.4	0.5	1.5	0.3	-1.1	0.9	-0.1	0.4	-0.3	0.6	1.2	-0.6
Supplements: Zinc	1.3	1.5	4.0	0.4	-0.3	0.9	-0.5	1.1	1.8	1.8	2.0	0.0
Medication: Co-codamol	1.0	1.2	3.7	-0.7	0.6	-1.4	-1.5	-1.0	1.1	-0.0	1.9	0.2
Medication: Metformin	0.4	0.5	1.4	0.5	-0.9	1.2	0.2	-0.2	0.6	0.2	1.1	-0.6
Diabetes (father)	0.3	0.4	1.2	-0.9	0.1	-0.7	-0.3	-0.2	1.0	-0.2	-1.1	0.2
Diabetes (mother)	0.5	0.6	1.4	-0.8	-0.3	-0.8	-0.6	0.7	0.8	0.6	1.2	-0.8
Severe depression (siblings)	0.7	0.8	1.9	0.0	-1.3	0.4	-0.3	-0.6	-1.1	0.2	1.1	-1.4
Pack years adult smoking proportion	1.5	2.3	5.0	1.6	-1.9	2.2	0.9	-0.2	0.0	2.0	1.6	-1.4
Impedance of leg (right)	0.7	3.4	13.6	1.1	-2.2	0.6	0.2	1.5	-2.8	0.6	0.4	-3.7
Leg fat-free mass (left)	3.7	19.7	48.3	-5.4	6.9	-3.6	-2.7	-4.5	1.5	-3.3	-3.4	5.9
Trunk fat percentage	0.4	1.5	3.3	-1.5	1.8	-1.8	-0.9	-0.8	0.4	-0.8	-0.6	1.3
Hand grip strength (right)	0.2	0.7	2.0	-1.4	0.7	-0.1	-1.4	-0.7	0.4	0.0	0.9	-0.4
Townsend deprivation index at recruitment	0.4	0.6	1.8	-1.3	0.1	0.7	-0.7	-0.3	-0.4	0.3	0.3	-1.4
Current tobacco smoking	0.4	0.7	2.2	-0.6	0.6	-0.4	-0.2	-0.7	-1.5	-0.6	-1.3	-0.7
Average weekly fortified wine intake	2.0	2.3	4.1	1.6	-2.0	1.4	1.0	1.9	-1.0	1.3	1.1	-1.9
Maternal smoking around birth	0.6	0.9	2.6	1.0	-1.5	0.7	1.0	-0.0	-0.7	0.3	0.5	-1.6
Fed-up feelings	1.8	3.2	6.9	-0.7	2.6	-1.1	0.4	-1.9	0.3	-1.7	-2.6	2.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.3	0.1	0.7	1.5	-0.2	-0.5	1.3	0.2	-0.3	0.4
Relative age voice broke	0.8	1.3	6.0	1.4	0.0	1.0	2.5	0.2	0.5	1.2	-0.1	0.8
Taking other prescription medications	0.2	0.3	1.5	0.1	0.4	0.2	-0.5	-0.2	0.3	-1.2	-0.3	0.4
Age when periods started (menarche)	0.5	1.1	4.2	0.4	-0.2	2.0	0.2	1.3	1.3	0.9	0.9	-0.8
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	6.8	2.6	-0.8	1.4	2.1	1.1	1.1	1.9	1.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	4.0	1.3	-1.0	-0.3	1.3	2.0	-0.6	0.2	-0.6	-0.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.6	0.8	-0.4	1.2	0.3	1.6	1.9	0.6	0.6	1.0
Qualifications: CSEs or equivalent	1.3	1.8	5.3	-2.3	0.3	-1.6	-2.2	-1.4	0.6	-0.7	-0.1	-0.3
Serious illness, injury or assault to yourself	1.0	1.2	2.8	-1.4	1.4	-1.0	-1.0	-1.2	0.3	-0.6	0.3	1.7
High blood pressure	0.3	0.8	3.0	-0.7	0.3	-0.7	-0.9	-1.7	1.2	-0.2	1.0	0.1
Hayfever, allergic rhinitis or eczema	2.1	4.5	13.9	2.4	0.2	0.8	3.7	2.3	-1.7	1.0	-3.0	1.4
Multivitamins +/- minerals	0.4	0.6	2.0	-0.7	0.8	-0.6	0.3	-0.6	-0.2	-0.3	-1.4	1.0
Stomach or abdominal pain in last month	2.7	3.4	6.5	-2.0	2.3	-1.9	-1.9	-2.4	-0.1	-2.5	-1.2	1.0
Supplements: Glucosamine	1.8	2.3	5.6	0.1	1.6	-1.4	0.8	-1.0	-2.1	-1.2	-2.4	1.9
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	6.2	-1.4	1.9	-1.1	-0.9	-2.5	0.3	-1.5	-1.3	1.3
Medication: Atenolol	1.7	2.1	5.3	1.3	-1.3	0.7	1.5	2.2	0.8	2.3	1.4	-0.4
Medication: Levothyroxine sodium	0.8	1.4	4.9	0.5	-1.5	1.5	-0.2	0.5	0.5	0.6	1.5	-2.2
Sitting height	3.2	22.5	54.2	-5.7	7.4	-3.2	-2.8	-5.4	-1.2	-3.4	-4.5	5.9
Chronic bronchitis/emphysema (father)	0.3	0.3	1.4	0.7	-0.9	-0.2	0.1	0.4	0.0	-0.1	-0.2	-1.2
High blood pressure (mother)	1.4	1.9	7.5	-1.0	1.1	-1.9	-1.6	-2.7	-0.2	-1.3	-0.1	0.2
Body mass index (BMI)	0.7	3.2	9.6	-1.9	1.7	-1.2	-0.8	-1.1	3.1	-0.1	0.5	3.0
Impedance of leg (left)	0.9	4.3	14.3	1.5	-2.3	1.2	0.5	2.1	-3.1	0.9	0.3	-3.8
Leg predicted mass (left)	3.7	19.5	47.9	-5.4	6.9	-3.6	-2.6	-4.5	1.6	-3.2	-3.4	5.9
Trunk fat mass	1.3	5.6	13.4	-3.0	3.7	-2.4	-1.7	-2.1	0.8	-1.7	-1.6	3.0
Waist circumference	1.0	3.6	8.0	-2.8	2.8	-1.4	-1.2	-1.4	1.9	-0.2	-0.1	2.8
Number of incorrect matches in round	1.1	1.8	6.4	1.2	0.5	2.5	2.1	-0.3	-0.6	1.7	-0.6	0.1
Past tobacco smoking	0.1	0.2	0.8	-0.1	0.9	0.1	-0.4	-0.2	-0.4	-0.6	-0.6	0.5
Alcohol usually taken with meals	0.4	0.7	1.8	0.6	0.9	-0.1	1.0	-1.1	-0.4	-0.5	-0.7	1.4
Nervous feelings	0.6	1.2	3.3	1.2	-0.6	1.8	1.6	1.5	-0.5	0.8	0.1	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.6	-0.7	0.5	-0.2	-1.3	-0.7	-0.3	-0.6	-0.3	-0.2
Hearing difficulty/problems with background noise	2.2	3.5	6.0	-2.5	2.1	-1.1	-2.4	-1.4	-2.1	-2.0	-1.4	-1.2
Hair/balding pattern: Pattern 2	2.2	2.8	5.8	1.7	-2.2	1.0	2.0	2.0	-2.4	1.1	-0.2	-1.3
Had menopause	1.0	1.3	4.0	1.7	-0.8	0.4	1.5	0.3	-2.0	0.2	-0.7	-1.0
Had other major operations	0.3	0.4	1.4	0.2	1.2	-0.8	0.1	-0.6	0.9	0.0	-0.0	0.6
Forced vital capacity (FVC)	2.1	8.1	21.5	-2.3	4.6	-2.4	-1.2	-3.1	0.3	-2.2	-2.7	4.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.4	0.8	-0.7	-1.0	0.8	1.2	-0.4	-0.1	-0.2	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.3	-1.0	-0.2	-0.7	-1.1	-0.1	-0.6	-0.8	0.5	-1.1
Qualifications: None of the above	0.6	1.3	8.4	0.6	0.9	0.9	0.3	-0.8	2.9	0.3	0.4	0.9
Financial difficulties in last 2 years	1.8	2.4	4.8	-1.9	2.1	-0.7	-1.3	-2.2	1.3	-1.3	-0.6	1.8
Mouth/teeth dental problems	0.3	0.5	2.1	-0.6	-0.4	-1.0	-0.3	1.5	-0.5	-0.1	0.5	-0.7
Heart attack	0.9	1.2	5.1	0.0	-2.3	0.7	-0.5	0.7	-1.2	0.3	0.8	-1.4
Allergy	1.9	4.5	14.2	-2.6	0.6	-2.3	-3.8	-2.3	0.4	-2.0	1.5	-1.2
Pain all over the body in last month	0.5	0.6	1.7	-0.1	1.1	0.6	0.3	-0.3	0.6	-0.7	-0.8	1.3
Diabetes (self-reported)	0.6	0.9	4.4	-0.4	0.2	0.6	-0.5	-0.9	2.1	-0.1	1.1	0.8
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	10.8	0.7	1.1	-0.5	1.6	0.0	-1.9	-1.4	-3.3	0.6
Medication: Ramipril	1.0	1.3	3.4	0.5	-1.8	0.6	0.7	1.5	-1.1	1.2	0.5	-1.4
Medication: Simvastatin	4.2	6.1	20.0	1.2	-4.5	2.5	0.2	1.5	-1.6	1.6	3.3	-2.9
Fluid intelligence score	0.9	1.8	3.9	1.7	0.1	0.8	1.6	1.7	-2.0	0.1	-1.1	1.4
Illnesses of siblings	1.3	1.9	3.8	-1.7	1.7	-0.8	-1.2	-0.9	-1.3	-1.9	-1.6	-0.3
Neuroticism score	0.4	0.8	3.3	0.4	-0.3	1.8	1.3	0.4	-0.8	0.6	-1.0	-0.6
Weight	3.2	15.8	39.1	-5.0	6.2	-3.2	-2.3	-3.9	1.6	-2.5	-2.8	5.6
Impedance of arm (right)	0.7	3.2	15.6	1.2	-0.8	-0.9	0.5	0.8	-4.0	-0.5	-1.5	-2.6
Arm fat percentage (right)	0.4	1.5	3.4	-1.4	1.2	-1.9	-0.8	-0.9	1.3	-0.7	-0.1	1.6
Trunk fat-free mass	4.2	23.8	58.5	-6.3	7.7	-3.4	-3.1	-5.0	1.6	-3.4	-3.6	6.5
Hip circumference	3.8	16.3	34.7	-5.1	5.9	-3.9	-2.9	-3.8	2.2	-3.1	-2.2	5.4
Time employed in main current job	0.3	0.3	1.5	-0.1	0.1	0.6	0.4	0.5	0.6	0.0	0.2	1.2
Alcohol intake versus 10 years previously	1.0	1.5	4.5	-1.4	1.5	-2.1	-1.8	-0.8	0.3	-1.1	-0.2	0.0
Father’s age at death	1.2	1.6	5.7	-0.6	1.7	-0.4	0.2	-1.2	-0.7	-1.2	-2.4	1.4
Worrier / anxious feelings	1.4	2.6	5.1	1.4	-0.4	2.1	2.2	1.8	-1.8	1.2	-1.3	-1.4
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	2.6	-1.0	0.6	-0.5	-1.6	-1.6	0.4	-1.0	0.3	-0.7
Falls in the last year	0.4	0.5	1.1	-0.8	-0.5	-0.8	-0.9	-1.0	-0.6	-1.0	0.1	-0.6
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	-0.1	0.1	0.1	-0.0	0.5	-0.0	0.0	-0.5	0.7
Number of live births	1.5	2.1	4.2	1.7	-1.4	1.6	-0.5	0.8	1.8	0.2	2.1	-1.8
Forced expiratory volume in 1-second (FEV1)	2.4	8.2	21.3	-2.5	4.3	-2.9	-1.4	-2.7	0.9	-2.0	-2.2	4.6
Pulse rate	0.5	0.9	2.8	-0.0	-0.5	1.1	0.9	0.8	0.6	1.7	1.0	0.9
Happiness	0.1	0.2	0.5	-0.3	-0.4	0.6	0.1	0.1	-0.7	0.3	-0.0	-0.4
Noisy workplace	0.3	0.4	1.0	-0.2	-0.9	0.2	-0.8	-1.0	-0.6	0.2	0.5	-0.3
Qualifications: A levels/AS levels or equivalent	0.8	1.8	10.6	-0.0	0.1	-0.7	0.1	0.9	-3.3	-0.9	-1.3	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.1	-1.2	1.1	-0.7	-1.8	-0.2	0.3	-1.1	-0.4	0.6
Mouth/teeth dental problems: Dentures	0.3	0.6	1.5	1.2	-0.3	1.2	1.0	0.4	-0.0	0.8	0.2	-0.7
Asthma	1.1	2.3	5.9	-1.4	2.2	-0.1	0.1	-0.9	1.6	-0.8	-1.9	2.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.8	-0.1	0.9	-0.8	-0.0	0.0	-0.1	-0.2	0.1	0.3
Medication: Cholesterol lowering	5.7	8.8	30.7	2.2	-5.5	2.0	0.6	3.1	-1.4	1.8	3.5	-3.5
Depression (self-reported)	0.7	0.8	3.0	-0.8	-0.2	0.1	-1.3	-0.2	-0.7	-1.7	-0.2	-1.3
Medication: Lansoprazole	0.8	0.9	3.9	0.9	0.1	-0.1	0.5	-0.3	2.0	0.5	0.3	1.6
Prospective memory result	0.5	0.6	1.5	-0.6	0.4	-1.2	-0.5	-1.1	-0.1	-1.2	-0.7	-0.1
Lung cancer (father)	1.1	1.3	2.9	1.1	-0.6	1.7	1.2	1.3	-0.1	1.3	0.4	-1.4
Illnesses of mother	0.5	0.6	2.0	-0.1	0.3	1.1	0.4	0.3	1.4	0.3	0.1	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	3.1	9.9	29.9	-3.0	4.6	-2.4	-1.3	-3.1	1.5	-1.9	-2.3	5.5
Pulse wave Arterial Stiffness index	0.7	0.9	4.2	-1.2	0.8	0.4	-0.9	-2.1	-0.1	-0.6	0.0	0.5
Impedance of arm (left)	0.7	3.4	16.4	1.3	-0.5	-0.8	0.3	0.9	-4.1	-0.6	-1.3	-2.9
Arm fat mass (right)	1.3	5.5	11.6	-3.0	3.2	-2.3	-1.4	-2.1	1.8	-1.4	-1.1	3.4
Trunk predicted mass	4.2	24.2	59.0	-6.3	7.7	-3.4	-3.1	-5.2	1.5	-3.4	-3.6	6.6
Standing height	4.0	40.1	110.2	-7.0	10.5	-4.7	-3.1	-6.6	-2.6	-5.0	-7.3	6.4
Length of working week for main job	0.2	0.2	0.7	0.0	-0.4	-0.8	0.0	0.8	0.7	0.3	0.4	0.0
Exposure to tobacco smoke at home	0.9	1.0	4.7	0.5	-0.7	2.2	-0.2	-0.1	0.8	0.9	1.4	-0.6
Breastfed as a baby	0.1	0.2	0.8	-0.2	0.1	-0.1	-0.1	0.7	0.0	0.1	0.3	-0.9
Tense / ‘highly strung’	0.9	1.5	3.4	1.4	-1.5	1.3	1.8	1.0	-1.3	0.7	-0.8	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	4.8	-0.4	-0.0	-0.9	-0.4	0.5	-2.2	-0.5	-0.2	-1.5
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-0.9	0.8	-0.5	-0.9	-0.4	1.0	-0.5	0.4	0.6
Birth weight of first child	1.9	3.4	18.1	-0.7	2.7	-0.7	0.5	-1.1	1.4	-0.3	-1.1	4.3
Peak expiratory flow (PEF)	2.6	6.1	18.5	-1.5	3.4	-2.5	-0.6	-2.5	1.9	-1.9	-1.6	4.3
Pulse wave reflection index	1.1	1.3	3.6	-1.6	1.3	-0.8	-1.1	-1.9	-0.2	-1.1	-0.6	0.7
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.4	0.4	-0.6	-0.0	-1.1	-0.4	0.9	-0.9	1.3	-1.6
Loud music exposure frequency	0.5	0.6	2.4	-0.7	-0.3	0.6	-0.4	-0.2	1.6	0.5	0.5	0.9
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.9	-2.2	2.0	-1.2	-1.4	-0.9	-2.1	-2.1	-2.0	-0.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.8	0.7	-0.6	-0.3	1.2	-0.5	0.2	0.8	0.6	1.4
Blood clot in the leg (DVT)	6.7	8.6	20.8	2.2	-4.6	3.3	1.0	2.3	0.9	3.9	3.9	-2.0
Medication: Paracetamol	0.3	0.6	2.3	0.1	-0.0	1.1	-0.0	-0.2	1.5	0.9	0.4	0.8
Headache pain in last month	0.3	0.6	1.5	0.1	0.8	0.9	0.3	0.7	1.1	0.4	-0.5	1.2
Medication for cholesterol, blood pressure or diabetes	1.7	2.9	10.1	-1.6	3.2	-0.8	-0.8	-2.1	1.3	-0.5	-1.1	2.1
Glaucoma (self-reported)	0.1	0.1	0.2	0.2	-0.4	0.2	0.4	0.3	-0.2	0.4	0.4	-0.2
Gout (self-reported)	0.2	0.3	1.4	-0.3	0.4	-0.5	-0.1	-0.2	0.9	-0.2	-0.2	1.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.7	0.3	-0.6	1.0	0.6	0.0	-0.7	0.1	-0.0	-1.3
Medication: Amlodipine	0.1	0.1	0.4	0.0	-0.0	-0.2	0.4	-0.5	0.2	0.2	-0.6	0.2
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.6	-0.8	1.9	-0.3	-0.1	-1.4	0.6	-0.7	-1.8	1.2
Birth weight	0.8	1.6	3.9	-0.9	1.9	0.3	0.7	-2.0	-0.3	0.5	-1.2	2.0
Chronic bronchitis/emphysema (mother)	1.5	1.7	4.9	-1.0	1.5	-1.1	-0.0	-1.8	-0.8	-1.4	-2.2	0.4
High blood pressure (siblings)	0.2	0.3	0.8	0.6	-0.7	-0.9	0.3	-0.0	-0.7	0.2	0.0	0.0
Forced vital capacity (FVC), Best measure	2.9	10.7	25.7	-3.2	5.1	-2.5	-1.6	-3.5	1.0	-2.5	-2.8	4.8
Body fat percentage	0.2	0.8	1.8	-1.3	1.1	-1.4	-0.8	-0.4	0.6	-0.5	-0.1	0.9
Leg fat percentage (right)	0.1	0.5	1.8	-0.7	-0.4	-0.2	-0.4	-0.0	1.3	0.7	1.2	0.5
Arm fat-free mass (right)	3.8	19.5	49.1	-5.8	7.0	-2.7	-2.7	-4.5	1.6	-3.3	-3.4	5.8
Exposure to tobacco smoke outside home	0.6	0.7	3.8	0.0	-0.7	1.2	-0.3	0.1	1.9	0.0	0.7	-0.5
Comparative body size at age 10	0.2	0.5	2.2	-0.6	0.1	-0.0	0.7	-0.1	-1.1	-0.0	-1.5	0.6
Number of full brothers	1.3	1.7	5.2	0.8	-2.3	1.7	0.0	1.0	0.2	1.1	1.6	-1.2
Worry too long after embarrassment	1.0	1.7	4.5	1.3	-0.9	2.1	1.9	0.7	-1.4	0.5	-0.9	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.4	5.6	0.8	-1.6	1.5	-0.4	1.5	-0.6	1.7	2.1	-2.4
Wheeze or whistling in the chest in last year	1.8	3.3	7.8	-2.5	2.8	-1.2	-1.2	-1.6	-0.2	-1.5	-2.4	1.5
Number of children fathered	1.5	1.7	3.4	1.8	-1.4	0.6	1.7	1.5	-1.6	1.4	0.1	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.8	-1.0	-0.4	0.6	-0.7	0.3	0.3	-0.3	1.1	-1.4
Age at first live birth	0.9	1.7	7.3	-0.8	0.6	-1.5	-0.7	-0.6	-2.7	-1.2	-1.3	-0.4
Pulse wave peak to peak time	0.4	0.5	2.8	0.6	-0.1	-0.7	0.6	1.7	-0.1	0.2	-0.5	-0.1
Health satisfaction	0.1	0.1	0.4	0.1	-0.1	-0.4	0.2	-0.7	-0.0	-0.2	0.4	0.6
Shortness of breath walking on level ground	0.7	0.9	2.3	0.7	-0.3	1.1	0.2	-0.8	1.3	0.9	1.5	0.7
Qualifications: College or University degree	1.2	3.8	7.2	2.2	-2.0	1.8	2.3	2.6	-2.7	1.3	0.1	-1.1
Eye problems/disorders: None of the above	0.3	0.3	0.9	0.7	-0.1	-0.4	0.9	-0.2	-0.3	0.6	-0.3	1.0
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.7	-0.3	1.1	0.3	0.1	-1.6	-0.1	-0.2	-0.4	2.2
Emphysema/chronic bronchitis	2.4	2.7	5.0	2.2	-2.1	2.0	2.0	0.9	-0.8	2.0	0.7	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.6	1.4	0.1	1.0	-1.0	0.7	-0.8	0.1	0.1	-0.6	1.2
Neck or shoulder pain in last month	6.2	8.8	20.1	-2.6	3.8	-3.4	-1.9	-4.5	0.0	-2.6	-2.4	3.2
Medication: Blood pressure	0.6	1.1	3.5	1.3	-1.9	1.1	1.0	1.0	0.2	0.4	0.5	-0.9
Angina (self-reported)	1.1	1.5	4.4	0.1	-1.8	0.8	-1.2	0.5	-0.5	-0.1	1.6	-2.1
Migraine (self-reported)	0.1	0.2	0.6	0.8	0.5	0.4	0.5	0.2	0.0	0.4	-0.5	0.3
Medication: Ibuprofen	0.2	0.2	0.6	0.6	0.5	-0.1	0.7	0.4	-0.1	0.5	0.2	0.4
Medication: Allopurinol	0.7	0.9	4.5	-0.1	-0.3	0.4	0.4	0.3	2.1	0.6	0.5	1.6
Medication: Omeprazole	1.1	1.3	3.1	-1.5	0.6	-1.1	-1.8	-1.2	-0.4	-1.8	0.0	0.3
Medication: Seretide 50 evohaler	0.2	0.3	0.7	0.6	-0.5	-0.2	-0.9	-0.1	0.4	-0.8	0.4	0.1
Mean time to correctly identify matches	3.3	6.4	14.5	2.4	-3.8	2.6	1.4	2.3	-0.4	3.3	2.7	-2.2
Heart disease (mother)	2.7	3.3	12.4	-0.5	-2.8	-0.5	-1.7	-0.2	-2.1	-0.6	1.2	-3.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.3	1.6	7.2	2.7	-0.9	1.0	1.9	0.8	-0.6	0.5	0.1	-0.0
Whole body fat mass	1.1	4.4	10.0	-2.9	3.2	-2.1	-1.5	-1.8	1.1	-1.4	-1.2	2.7
Leg fat mass (right)	0.8	3.1	6.9	-2.5	2.4	-1.3	-1.1	-1.6	1.6	-0.8	-0.5	2.6
Arm predicted mass (right)	3.5	17.9	45.7	-5.7	6.8	-2.5	-2.9	-4.2	1.6	-3.1	-3.0	5.5
Pulse rate, automated reading	1.0	3.4	11.8	-1.8	1.8	-0.2	-0.2	-1.0	3.4	1.0	1.0	3.0
Alcohol intake frequency.	0.6	1.5	4.7	-1.2	1.0	0.2	-2.2	-1.0	1.9	0.1	1.1	0.1
Comparative height size at age 10	3.1	17.3	48.0	-5.4	6.9	-2.9	-2.7	-4.3	-1.6	-3.1	-4.3	3.8
Number of full sisters	2.3	2.8	6.9	0.9	-2.6	1.6	0.1	2.3	0.4	1.3	2.0	-2.0
Suffer from ‘nerves’	0.4	0.6	2.6	-0.6	1.0	0.5	0.7	-0.6	-0.0	0.3	-0.8	1.6
Overall health rating	1.4	3.0	6.7	-1.9	1.7	-2.4	-1.4	-2.6	0.9	-1.3	-0.4	2.0
Chest pain or discomfort	0.9	1.3	3.0	-1.6	0.7	-1.1	-1.7	-1.6	-0.6	-1.2	-0.1	-0.2
Had major operations	2.2	2.6	4.9	-0.6	2.1	-1.7	-0.1	-1.6	0.3	-2.2	-2.1	1.9
Age at last live birth	0.9	1.3	4.8	-0.7	-0.3	-0.9	-1.6	-0.9	-1.0	-1.2	0.3	-2.2
Family relationship satisfaction	1.1	1.3	3.0	-1.0	1.2	-1.7	-0.7	-1.6	-0.2	-1.3	-1.0	0.9
Leg pain on walking	1.5	1.9	8.8	-0.8	0.0	-0.2	-1.2	-1.3	3.0	-0.3	1.9	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	6.9	-0.8	-1.6	0.2	-1.5	-0.2	0.6	1.4	2.6	-1.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.0	-0.2	-0.2	-0.4	-0.2	0.3	-0.4	-0.8	-0.2	-1.0
Illness, injury, bereavement, stress in last 2 years	3.5	4.3	8.1	2.8	-2.4	1.9	2.7	2.7	-0.7	2.1	0.9	-0.9
Medication: Aspirin	1.2	1.5	5.1	-0.2	-2.0	1.5	-0.5	0.8	-0.8	0.0	1.1	-2.3
Supplements: Vitamin C	0.4	0.5	1.9	-0.2	-0.3	-0.4	-0.7	-0.4	1.4	-0.4	0.9	-0.7
Knee pain experienced in last month	6.9	10.7	25.9	-3.6	4.5	-3.2	-1.6	-3.2	1.0	-2.3	-2.7	5.1
Hypertension (Self-reported)	0.3	0.8	3.1	-0.6	0.3	-0.9	-0.7	-1.8	1.2	0.1	1.0	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.7	0.9	-1.7	1.0	-0.0	0.3	-0.5	1.5	1.6	-1.1
Illnesses of father: Heart disease	3.1	4.4	15.4	2.3	-3.9	0.5	0.5	2.0	-0.6	1.5	2.9	-1.8
Illnesses of siblings: Diabetes	1.2	1.5	3.1	1.2	-1.6	1.5	0.8	1.2	0.6	1.7	0.9	-1.0
Smoking status: Previous	0.3	0.4	1.3	0.5	-0.7	0.1	0.7	0.2	0.6	1.1	0.7	0.2
Forced expiratory volume in 1-second (FEV1), predicted	5.0	10.3	20.5	-4.5	4.3	-2.4	-3.8	-3.3	-0.2	-3.8	-2.4	1.8
Whole body fat-free mass	4.1	23.2	57.3	-6.2	7.6	-3.5	-3.0	-4.9	1.7	-3.4	-3.6	6.4
Leg fat-free mass (right)	3.7	19.6	51.1	-5.3	7.2	-3.3	-2.6	-4.3	1.6	-3.1	-3.4	6.0
Arm fat percentage (left)	0.3	1.3	3.0	-1.3	1.3	-1.7	-0.7	-0.7	1.3	-0.6	-0.1	1.6
Average weekly red wine intake	0.2	0.2	0.8	-0.6	0.2	-0.4	-0.5	-0.1	0.2	-0.6	-0.1	0.9
Handedness (chirality/laterality): Left-handed	2.2	2.6	6.4	2.5	-1.8	2.2	1.4	1.5	-0.1	1.3	0.6	-1.7
Mood swings	0.8	1.4	4.3	1.1	-1.2	2.1	1.1	0.7	0.5	1.7	0.9	-0.5
Loneliness, isolation	1.1	1.5	4.1	-1.3	1.0	-0.9	-0.5	-2.0	-0.8	-1.8	-1.3	0.2
Long-standing illness, disability or infirmity	0.3	0.5	1.7	-0.0	-0.1	0.0	-0.4	0.4	1.3	0.9	1.1	0.6
Ever had bowel cancer screening	0.7	0.9	1.7	1.0	-0.4	1.3	0.4	-0.8	1.2	1.1	1.1	0.7
Diabetes diagnosed by doctor	0.6	1.1	3.2	-1.1	0.8	-0.0	-1.3	-1.2	1.8	-0.9	0.8	0.2
Ever had stillbirth, spontaneous miscarriage or termination	2.8	2.9	9.7	0.8	-2.6	0.8	-0.3	0.9	-2.7	0.4	0.7	-3.1
Friendships satisfaction	2.1	2.6	5.0	-1.7	0.9	-2.2	-1.4	-2.2	-1.7	-2.0	-1.0	-0.0
Qualifications: nursing, teaching	0.6	0.9	3.8	-0.3	1.0	-0.9	0.2	0.1	-2.0	-0.8	-1.2	-0.4
Commuting to job workplace: Walk	1.9	2.1	4.8	1.4	-1.8	0.8	0.2	2.2	0.1	1.3	1.9	-1.8
Eye problems/disorders: Cataract	0.4	0.5	1.5	0.2	-1.2	0.4	0.1	0.6	-0.5	0.0	0.4	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	1.8	-0.9	0.9	0.8	-1.2	-1.3	-0.0	-0.6	-0.8	0.1
Medication for cholesterol	1.7	2.5	7.4	1.7	-0.7	0.9	1.8	2.7	-1.5	0.1	-1.5	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.5	0.7	0.6	-0.5	0.5	0.7	-1.0	-0.6	-1.2	-0.4
Back pain experienced in last month	0.2	0.2	0.8	0.0	0.2	0.6	-0.2	0.3	0.3	0.9	0.7	0.4
Mineral and other dietary supplements	0.7	1.0	2.6	-0.1	-1.6	1.0	-0.7	0.3	0.7	0.3	1.3	-1.6
Breast cancer (self-reported)	0.5	0.6	2.8	0.4	0.0	-0.1	0.5	-1.4	-1.7	0.3	-0.1	0.7
Asthma (self-reported)	1.1	2.1	5.1	-1.3	2.2	-0.2	0.2	-1.0	1.4	-0.9	-2.0	2.3
Osteoporosis (self-reported)	0.6	0.8	2.4	1.2	0.7	0.2	1.6	-0.4	0.6	-0.2	-1.2	0.9
Osteoarthritis (self-reported)	5.0	6.5	20.5	-2.2	3.8	-1.8	-0.6	-2.2	1.9	-1.9	-1.9	4.5
Medication: Aspirin	1.9	2.4	8.2	0.2	-2.3	1.9	-0.4	1.3	-1.0	0.2	1.3	-2.9
Medication: Gliclazide	1.1	1.2	3.3	-1.8	1.2	-0.3	-1.6	-0.7	1.4	-0.4	0.8	0.5
Illnesses of father: None of the above (group 1)	2.8	3.4	15.2	-1.6	3.9	0.1	-0.1	-2.0	-0.4	-0.8	-2.0	2.1
Smoking status: Current	0.5	0.8	1.6	-1.0	0.8	-0.8	-0.5	-0.9	-1.3	-0.9	-1.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	7.2	0.8	0.6	-0.5	0.2	-0.4	2.1	0.7	0.7	2.7
Whole body water mass	4.0	22.8	56.9	-6.1	7.5	-3.4	-3.0	-4.8	1.6	-3.4	-3.6	6.3
Leg predicted mass (right)	3.7	19.7	51.1	-5.3	7.1	-3.3	-2.6	-4.4	1.6	-3.2	-3.5	6.0
Arm fat mass (left)	1.6	6.4	13.6	-3.2	3.7	-2.4	-1.6	-2.4	1.6	-1.8	-1.3	3.5
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	-0.1	-0.0	0.6	-0.4	0.1	1.1	0.5	0.8	-0.3
Average weekly champagne plus white wine intake	0.7	1.0	2.5	1.6	-1.4	0.6	1.3	1.0	-0.0	0.8	0.9	0.3
Miserableness	0.3	0.4	1.4	-0.8	0.3	0.0	-0.8	-1.2	0.1	-0.9	-0.3	-0.3
Guilty feelings	0.4	0.6	2.8	0.7	-0.3	0.8	1.7	0.2	-0.3	0.1	-1.2	-0.5
Wears glasses or contact lenses	0.9	1.0	3.1	0.7	-1.3	0.9	-0.5	0.7	-1.3	-0.4	0.3	-1.8
Ever taken oral contraceptive pill	2.9	3.3	10.0	0.9	-2.4	0.2	-0.3	1.0	2.5	1.8	3.2	-1.4
Hearing aid user	0.8	1.0	3.2	-0.9	0.3	-1.1	-0.8	0.5	1.8	0.5	1.3	-0.6
Mother’s age at death	1.8	2.2	7.5	-0.5	1.8	-0.7	-0.3	-0.8	-2.7	-1.2	-2.5	0.2
Financial situation satisfaction	0.5	0.6	1.7	-0.5	0.5	-1.3	-0.7	-0.3	1.2	0.4	1.0	0.5
Tinnitus: Yes, now most or all of the time	3.0	3.5	11.5	-1.0	2.7	-1.0	-0.6	-3.4	1.1	-1.3	-1.7	2.2
Commuting to job workplace: Public transport	3.7	4.4	9.7	-0.8	2.9	-1.8	-0.4	-1.6	-2.0	-2.7	-3.1	1.9
Eye problems/disorders: Glaucoma	0.5	0.6	1.5	0.5	-0.5	0.8	0.3	1.0	0.1	0.9	1.2	-1.0
Medication: Blood pressure	1.0	2.0	5.2	-1.6	1.1	-1.0	-1.9	-2.3	1.6	-0.1	1.3	-0.2
Pain type(s) experienced in last month: Hip pain	1.4	1.8	5.2	-1.3	2.0	-1.1	-0.9	-1.2	0.8	-0.4	-0.6	2.3
Supplements: Fish oil (including cod liver oil)	1.5	2.0	4.5	-0.9	2.0	-1.2	0.1	-1.4	-1.2	-1.2	-2.1	1.6
High cholesterol (Self-reported)	5.5	9.7	31.6	1.1	-5.6	1.6	-0.8	2.0	-2.0	2.0	4.8	-4.0
Medication: Bendroflumethiazide	0.3	0.5	1.1	-0.9	0.8	0.2	-0.6	-1.0	1.0	-0.5	-0.5	0.3
Medication: Paracetamol	0.4	0.6	2.6	0.2	0.0	0.6	-0.2	-0.6	1.6	0.6	0.5	1.1
Medication: Lisinopril	0.5	0.6	1.4	-0.9	1.1	-0.4	-0.1	-1.2	0.2	-0.6	-0.6	1.1
Medication: Atorvastatin	4.0	4.9	14.3	1.9	-3.8	1.0	1.0	1.8	-0.3	2.4	3.4	-1.8
Illnesses of father: High blood pressure	0.2	0.2	1.3	-0.3	0.1	-0.1	0.3	0.2	1.1	0.4	0.4	0.5
Alcohol drinker status: Never	4.3	5.1	15.3	-3.2	2.3	-1.9	-3.9	-2.1	-0.1	-2.4	-0.8	-0.5
Ever smoked	0.1	0.1	0.6	-0.3	-0.2	0.1	0.8	0.2	0.3	0.5	-0.4	-0.2
Basal metabolic rate	4.0	22.2	54.6	-6.1	7.4	-3.5	-3.0	-4.8	1.7	-3.3	-3.4	6.2
Leg fat percentage (left)	0.1	0.4	1.3	-0.5	-0.3	0.1	-0.3	0.4	1.1	0.7	1.0	0.4
Arm fat-free mass (left)	4.0	20.5	50.4	-6.0	7.1	-2.9	-3.1	-4.7	1.6	-3.4	-3.2	5.8
Number of operations (self-reported)	0.4	0.6	1.4	1.2	0.8	-0.3	1.0	-0.4	-1.1	0.1	-0.9	0.4
Average weekly beer plus cider intake	0.4	0.6	2.8	0.5	0.2	1.7	0.1	-0.0	-0.3	-0.3	-0.7	-1.1
Irritability	2.4	4.0	8.2	2.5	-1.0	2.4	2.1	2.2	1.8	2.9	1.4	0.6
Risk taking	0.8	1.1	3.6	0.5	-1.2	1.3	0.4	1.1	-1.9	0.7	0.1	-0.9
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.3	1.5	-1.2	1.4	0.8	0.4	1.1	0.9	0.4	0.4
Fractured/broken bones in last 5 years	1.6	2.1	6.0	-0.9	2.0	-1.3	-1.4	-1.3	0.2	-2.4	-0.9	1.4
Age started oral contraceptive pill	1.5	1.8	6.2	-0.4	2.5	-1.1	0.2	-1.4	0.2	-2.0	-1.4	1.1
Diastolic blood pressure, automated reading	0.8	2.5	6.0	-2.4	1.9	-1.3	-1.2	-2.0	1.9	-0.5	0.4	1.4
Ever depressed for a whole week	0.7	0.9	2.5	-0.9	-0.7	-0.3	-1.2	0.2	-1.5	0.0	0.7	-1.6
Unable to work because of sickness or disability	0.4	0.5	2.0	-0.6	0.7	-0.2	0.1	-0.6	0.2	-0.6	-0.7	1.4
Commuting to job workplace: Cycle	0.9	1.1	2.9	-1.7	1.6	0.0	-1.0	-0.7	-0.2	-1.5	-0.9	-0.1
Myopia	0.9	1.3	3.3	1.4	-0.6	1.8	1.1	0.8	0.5	1.8	0.8	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.0	0.4	0.2	0.3	0.5	0.9	-0.8	-0.2	-1.0	0.1
Cholesterol lowering medication	3.0	4.4	17.7	-1.6	-2.6	-0.4	-2.8	-1.2	-0.6	0.1	4.2	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.3	-1.2	0.6	-0.8	-1.6	-1.3	-0.7	-2.1	-0.6	0.5
Pain experienced in last month	2.9	4.9	11.9	1.6	-3.2	1.6	0.4	2.3	-0.3	1.8	2.8	-3.5
Supplements: Calcium	0.5	0.5	1.0	0.8	0.2	0.7	0.7	1.0	0.3	0.8	1.0	0.6
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	0.3	-0.2	1.0	-0.4	0.3	-0.7	0.0	-0.1	-0.6
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.0	-0.0	-2.0	0.5	-0.4	0.3	-1.2	0.1	0.5	-1.2
Deep venous thrombosis (DVT) (self-reported)	5.7	7.4	18.4	1.9	-4.3	3.0	0.8	2.0	1.3	3.5	3.6	-1.9
Heart disease (siblings)	4.4	5.4	12.9	2.1	-3.4	2.2	0.3	1.1	1.6	2.3	3.6	-2.3
Alcohol drinker status: Previous	1.2	1.4	3.0	1.2	-1.5	1.7	0.4	0.7	1.1	1.3	1.5	-0.2
Pack years of smoking	1.0	1.5	4.0	1.3	-1.5	2.0	0.6	-0.7	-0.2	1.4	1.1	-1.4
Impedance of whole body	0.8	4.0	15.4	1.5	-1.5	-0.1	0.4	1.4	-3.9	-0.1	-0.8	-3.7
Leg fat mass (left)	0.7	2.7	6.2	-2.4	2.4	-1.1	-1.0	-1.2	1.4	-0.7	-0.6	2.5
Arm predicted mass (left)	4.2	21.5	51.8	-6.2	7.2	-2.9	-3.2	-4.8	1.6	-3.5	-3.4	6.0