Best TWAS P=4.57e-09 · Best GWAS P=2.16e-09 conditioned to 0.0319
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | SOGA2 | 0.14 | 0.09 | lasso | 5 | 0.08 | 1.2e-06 | -5.1 | -5.2 | 1.8e-07 | 0.79 | 0.11 | 0.88 | FALSE |
| 2 | GTEx | Nerve Tibial | SOGA2 | 0.17 | 0.08 | lasso | 7 | 0.05 | 1.5e-04 | -5.9 | 5.7 | 1.3e-08 | -0.84 | 0.02 | 0.97 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SOGA2 | 0.09 | 0.04 | lasso | 6 | 0.04 | 2.1e-06 | -5.9 | 5.9 | 4.6e-09 | -0.80 | 0.01 | 0.99 | TRUE |