Best TWAS P=1.28e-11 · Best GWAS P=2.74e-10 conditioned to 0.184
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | MICAL3 | 0.23 | 0.06 | lasso | 4 | 0.03 | 2.7e-02 | 6.2 | -6.8 | 1.3e-11 | -0.82 | 0.04 | 0.69 | TRUE |
| 2 | GTEx | Thyroid | MICAL3 | 0.18 | 0.13 | enet | 18 | 0.13 | 6.5e-10 | -5.8 | -6.6 | 4.5e-11 | -0.75 | 0.11 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MICAL3 | 0.10 | 0.06 | enet | 14 | 0.04 | 1.5e-03 | 6.3 | -5.4 | 8.7e-08 | -0.91 | 0.01 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MICAL3 | 0.10 | 0.09 | enet | 14 | 0.10 | 1.4e-09 | -5.8 | -5.9 | 4.3e-09 | -0.71 | 0.15 | 0.85 | FALSE |