Best TWAS P=2.37e-11 · Best GWAS P=2.25e-13 conditioned to 0.000693
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CTA-85E5.10 | 0.10 | 0.04 | lasso | 9 | 0.03 | 0.0019 | 5.873 | -6.7 | 2.4e-11 | -0.78 | 0.03 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ASCC2 | 0.04 | 0.00 | blup | 48 | 0.01 | 0.0111 | -0.001 | -5.4 | 5.6e-08 | -0.45 | 0.01 | 0.57 | FALSE |