TWAS
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Traits
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Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr2:100,193,898-101,629,737
Best TWAS P=8.74e-09 · Best GWAS P=3.24e-10 conditioned to 0.0105
100.2M
100.4M
100.6M
100.8M
101M
101.2M
101.4M
101.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Lung
LONRF2
0.08
0
lasso
6
0
0.24
-5.9
-5.8
8.7e-09
0.89
0.04
0.95
TRUE