[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr2:135,898,023-137,435,625

Best TWAS P=5.27e-11 · Best GWAS P=1.47e-08 conditioned to 0.0097

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Esophagus Mucosa	DARS	0.12	0.05	lasso	4	0.04	9.0e-04	5.3	5.4	5.6e-08	-0.49	0.05	0.89	FALSE
2	GTEx	Esophagus Muscularis	DARS	0.12	0.11	lasso	3	0.09	3.5e-06	5.3	5.4	8.4e-08	-0.48	0.04	0.96	FALSE
3	GTEx	Lung	DARS	0.07	0.05	lasso	4	0.05	5.8e-05	5.3	5.4	8.0e-08	-0.48	0.04	0.95	FALSE
4	GTEx	Nerve Tibial	DARS	0.13	0.06	lasso	5	0.05	3.2e-04	5.4	5.3	9.6e-08	-0.49	0.04	0.94	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	DARS	0.15	0.11	enet	4	0.10	3.0e-06	5.3	5.5	4.2e-08	-0.48	0.04	0.95	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DARS	0.10	0.12	lasso	1	0.11	1.7e-09	5.3	5.3	1.3e-07	-0.46	0.05	0.95	FALSE
7	GTEx	Thyroid	DARS	0.20	0.13	lasso	3	0.15	1.3e-11	5.3	5.5	3.6e-08	-0.50	0.05	0.95	FALSE
8	METSIM	Adipose	DARS	0.09	0.07	blup	311	0.09	4.6e-13	5.3	5.2	2.2e-07	-0.38	0.05	0.95	FALSE
9	NTR	Blood	MCM6	0.02	0.02	lasso	2	0.03	1.2e-08	4.3	5.2	1.7e-07	-0.55	0.09	0.91	FALSE
10	YFS	Blood	DARS	0.17	0.19	enet	36	0.19	8.2e-60	5.3	6.6	5.3e-11	-0.53	0.06	0.94	TRUE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	LCT	0.02	0.02	enet	3	0.03	7.6e-07	4.6	-5.2	2.0e-07	0.55	0.04	0.96	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DARS	0.04	0.05	lasso	2	0.05	3.5e-06	5.0	5.1	2.7e-07	-0.47	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DARS	0.10	0.08	enet	14	0.11	5.5e-12	5.3	5.3	9.3e-08	-0.48	0.02	0.98	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DARS	0.02	0.02	lasso	2	0.02	3.9e-03	5.3	5.3	9.1e-08	-0.48	0.01	0.93	FALSE
15	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DARS	0.08	0.10	lasso	4	0.09	8.8e-05	5.4	5.4	7.2e-08	-0.49	0.02	0.94	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	DARS	0.04	0.02	blup	40	0.01	2.1e-02	5.3	5.9	3.7e-09	-0.52	0.02	0.93	FALSE
17	The Cancer Genome Atlas	Soft Tissue Sarcoma	DARS	0.04	0.04	blup	40	0.04	1.6e-03	5.3	5.6	2.3e-08	-0.53	0.02	0.93	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	DARS	0.22	0.15	enet	13	0.19	4.1e-18	5.2	5.6	2.5e-08	-0.39	0.02	0.97	FALSE