Best TWAS P=4.77e-17 · Best GWAS P=6.29e-15 conditioned to 0.627
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | BOK | 0.20 | 0.12 | lasso | 4 | 0.12 | 1.4e-06 | -7.8 | -7.3 | 3.9e-13 | 0.97 | 0.00 | 1.00 | FALSE |
2 | METSIM | Adipose | BOK | 0.06 | 0.03 | lasso | 6 | 0.03 | 7.8e-06 | -7.8 | -8.4 | 4.8e-17 | 0.95 | 0.00 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | BOK | 0.19 | -0.01 | lasso | 4 | 0.01 | 1.2e-01 | -7.8 | -5.4 | 6.5e-08 | 0.86 | 0.00 | 0.77 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BOK | 0.07 | 0.04 | lasso | 5 | 0.03 | 1.8e-04 | 6.1 | -6.9 | 6.7e-12 | 0.76 | 0.01 | 0.97 | FALSE |