TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr2:241,805,851-243,048,760
Best TWAS P=4.77e-17 · Best GWAS P=6.29e-15 conditioned to 0.627
241.8M
242M
242.2M
242.4M
242.6M
242.8M
243M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
BOK
0.06
0.03
lasso
6
0.03
7.8e-06
-7.8
-8.4
4.8e-17
0.95
0.00
1.00
TRUE
1
GTEx
Adipose Visceral Omentum
BOK
0.20
0.12
lasso
4
0.12
1.4e-06
-7.8
-7.3
3.9e-13
0.97
0.00
1.00
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
BOK
0.07
0.04
lasso
5
0.03
1.8e-04
6.1
-6.9
6.7e-12
0.76
0.01
0.97
FALSE
3
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
BOK
0.19
-0.01
lasso
4
0.01
1.2e-01
-7.8
-5.4
6.5e-08
0.86
0.00
0.77
FALSE