TWAS
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Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
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→
chr3:40,537,829-41,986,787
Best TWAS P=2.55e-08 · Best GWAS P=1.31e-07 conditioned to 0.852
40.6M
40.8M
41M
41.2M
41.4M
41.6M
41.8M
42M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
CTNNB1
0.3
0
lasso
4
0.01
0.1
5.2
-5.6
2.6e-08
-0.94
0.02
0.55
TRUE