[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr4:17,104,059-18,507,692

Best TWAS P=3.23e-36 · Best GWAS P=5.71e-31 conditioned to 0.00173

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-10.7	12.6	3.2e-36	-0.76	0.04	0.65	TRUE
3	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-10.8	11.9	7.0e-33	-0.81	0.08	0.65	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	8.0	11.6	5.2e-31	-0.64	0.13	0.68	FALSE
14	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	7.7	11.3	1.8e-29	-0.66	0.04	0.64	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	8.0	11.2	5.2e-29	-0.65	0.21	0.68	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-11.0	-11.0	4.2e-28	0.88	0.03	0.47	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	7.7	10.9	1.1e-27	-0.58	0.26	0.26	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-10.8	10.9	1.5e-27	-0.83	0.03	0.88	FALSE
16	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	7.7	10.6	2.7e-26	-0.54	0.17	0.70	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-10.8	-10.5	7.2e-26	0.84	0.68	0.32	FALSE
5	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	7.7	9.9	5.1e-23	-0.52	0.10	0.76	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-10.9	-9.9	6.0e-23	0.76	0.01	0.76	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-11.0	-9.5	2.0e-21	0.84	0.04	0.94	FALSE
15	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	8.0	9.3	1.3e-20	-0.26	0.19	0.05	FALSE
4	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	8.0	9.1	9.3e-20	-0.36	1.00	0.00	FALSE
10	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	7.7	8.7	5.0e-18	-0.37	0.99	0.00	FALSE
8	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	7.7	8.4	4.1e-17	-0.37	0.14	0.37	FALSE
2	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	7.7	8.2	1.6e-16	-0.35	0.36	0.33	FALSE
18	YFS	Blood	DCAF16	0.02	0.02	lasso	1	0.01	1.1e-04	8.0	8.0	1.3e-15	-0.25	0.84	0.03	FALSE
13	GTEx	Skin Sun Exposed Lower leg	DCAF16	0.14	0.12	enet	14	0.12	5.4e-10	7.7	8.0	1.5e-15	-0.28	1.00	0.00	FALSE
9	GTEx	Esophagus Muscularis	DCAF16	0.16	0.14	lasso	3	0.14	9.3e-09	7.7	7.6	3.0e-14	-0.27	0.99	0.00	FALSE
7	GTEx	Breast Mammary Tissue (Female)	DCAF16	0.16	0.13	lasso	2	0.06	7.8e-03	7.7	7.5	8.6e-14	-0.27	0.06	0.10	FALSE
1	GTEx	Adipose Subcutaneous	DCAF16	0.21	0.15	lasso	3	0.17	5.1e-14	7.7	7.4	1.8e-13	-0.24	1.00	0.00	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	6.1	7.2	4.2e-13	-0.35	0.64	0.05	FALSE
11	GTEx	Pituitary	DCAF16	0.27	0.20	enet	15	0.19	1.3e-05	7.7	7.2	5.0e-13	-0.38	0.08	0.24	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	NCAPG	0.06	0.02	blup	34	0.04	1.0e-05	-11.0	-6.2	4.0e-10	0.68	0.11	0.20	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	NCAPG	0.03	0.04	enet	5	0.04	8.1e-09	-1.2	-5.2	2.1e-07	0.55	0.96	0.04	FALSE