Best TWAS P=3.77e-09 · Best GWAS P=3.12e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | NOA1 | 0.17 | 0.06 | lasso | 4 | 0.06 | 3.5e-04 | 5.3 | -5.7 | 9.9e-09 | 0.90 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Colon Transverse | REST | 0.26 | 0.04 | lasso | 9 | 0.10 | 1.9e-05 | -4.1 | -5.3 | 1.3e-07 | 0.64 | 0.12 | 0.71 | FALSE |
| 3 | GTEx | Muscle Skeletal | REST | 0.05 | 0.01 | enet | 9 | 0.02 | 3.9e-03 | -4.0 | -5.6 | 2.5e-08 | 0.85 | 0.02 | 0.96 | FALSE |
| 4 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -4.9 | 5.5 | 5.1e-08 | -0.73 | 0.30 | 0.70 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C4orf14 | 0.03 | 0.04 | lasso | 3 | 0.04 | 1.9e-05 | -5.9 | -5.9 | 3.8e-09 | 0.99 | 0.00 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -5.0 | -5.9 | 4.0e-09 | 0.77 | 0.11 | 0.49 | FALSE |