Best TWAS P=9.51e-08 · Best GWAS P=5.39e-06 conditioned to 0.898
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C5orf34 | 0.04 | 0.01 | enet | 4 | 0.03 | 1.5e-03 | -4.5 | -5.3 | 9.5e-08 | 0.84 | 0.01 | 0.55 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C5orf34 | 0.11 | 0.12 | enet | 13 | 0.11 | 2.9e-12 | -4.5 | -5.2 | 1.8e-07 | 0.96 | 0.02 | 0.96 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | NNT | 0.06 | 0.01 | enet | 7 | 0.02 | 9.0e-04 | -4.5 | -5.3 | 1.1e-07 | 0.75 | 0.01 | 0.75 | FALSE |
4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C5orf34 | 0.30 | 0.02 | enet | 14 | 0.06 | 2.2e-07 | -4.5 | -5.2 | 1.9e-07 | 0.77 | 0.02 | 0.80 | FALSE |