TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr5:43,243,774-43,940,059
Best TWAS P=9.51e-08 · Best GWAS P=5.39e-06 conditioned to 0.898
43.3M
43.4M
43.5M
43.6M
43.7M
43.8M
43.9M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
C5orf34
0.04
0.01
enet
4
0.03
1.5e-03
-4.5
-5.3
9.5e-08
0.84
0.01
0.55
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
NNT
0.06
0.01
enet
7
0.02
9.0e-04
-4.5
-5.3
1.1e-07
0.75
0.01
0.75
FALSE
2
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
C5orf34
0.11
0.12
enet
13
0.11
2.9e-12
-4.5
-5.2
1.8e-07
0.96
0.02
0.96
FALSE
4
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
C5orf34
0.30
0.02
enet
14
0.06
2.2e-07
-4.5
-5.2
1.9e-07
0.77
0.02
0.80
FALSE