[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure :

chr4:144,230,902-146,788,825

Best TWAS P=1.14e-30 · Best GWAS P=5.97e-40 conditioned to 6.12e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GYPA 0.20 0.06 blup 293 0.10 4.0e-12 -3.0 -5.9 2.8e-09 0.34 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex OTUD4 0.06 0.04 bslmm 272 0.04 2.6e-05 -9.3 -8.9 5.4e-19 0.35 0.24 0.73 FALSE
3 GTEx Brain Hypothalamus HHIP-AS1 0.12 0.02 enet 16 0.04 4.6e-02 8.9 11.5 1.1e-30 -0.61 0.06 0.20 TRUE
4 GTEx Pancreas ANAPC10 0.14 0.10 lasso 3 0.10 4.3e-05 -9.7 9.4 5.9e-21 -0.39 0.34 0.05 FALSE
5 ROSMAP Brain Pre-frontal Cortex OTUD4 0.04 0.03 lasso 2 0.03 1.4e-04 8.2 -8.4 4.0e-17 0.26 0.35 0.48 TRUE