Best TWAS P=1.14e-30 · Best GWAS P=5.97e-40 conditioned to 6.12e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GYPA | 0.20 | 0.06 | blup | 293 | 0.10 | 4.0e-12 | -3.0 | -5.9 | 2.8e-09 | 0.34 | 1.00 | 0.00 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -9.3 | -8.9 | 5.4e-19 | 0.35 | 0.24 | 0.73 | FALSE |
| 3 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 8.9 | 11.5 | 1.1e-30 | -0.61 | 0.06 | 0.20 | TRUE |
| 4 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -9.7 | 9.4 | 5.9e-21 | -0.39 | 0.34 | 0.05 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 8.2 | -8.4 | 4.0e-17 | 0.26 | 0.35 | 0.48 | TRUE |