[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr5:147,012,186-148,712,150

Best TWAS P=4.49e-21 · Best GWAS P=2.35e-26 conditioned to 0.000562

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FBXO38	0.05	0.01	blup	489	0.02	1.5e-03	7.8	-8.8	2.1e-18	-0.72	0.02	0.97	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HTR4	0.06	0.03	lasso	4	0.03	4.3e-05	10.0	9.3	8.9e-21	0.79	0.01	0.98	TRUE
3	GTEx	Cells Transformed fibroblasts	FBXO38	0.18	0.05	enet	35	0.10	1.1e-07	7.8	-6.6	4.6e-11	-0.60	0.62	0.35	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	SPINK9	0.08	0.07	enet	21	0.07	1.4e-09	7.2	6.8	7.5e-12	0.48	1.00	0.00	FALSE
5	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FBXO38	0.04	0.04	blup	52	0.04	4.8e-03	7.8	-9.0	2.0e-19	-0.75	0.05	0.14	FALSE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	FBXO38	0.05	0.02	lasso	2	0.02	4.3e-02	7.2	-9.4	4.5e-21	-0.77	0.04	0.31	TRUE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FBXO38	0.02	0.03	enet	2	0.03	1.9e-04	-7.1	-8.3	1.0e-16	-0.76	0.04	0.59	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FBXO38	0.03	0.01	enet	6	0.01	5.0e-02	8.1	-6.8	1.3e-11	-0.53	0.08	0.04	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	FBXO38	0.11	0.02	blup	52	0.04	8.2e-06	7.9	-5.8	4.8e-09	-0.53	0.68	0.08	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	FBXO38	0.03	0.02	blup	51	0.02	7.7e-04	7.2	-8.2	3.7e-16	-0.63	0.54	0.08	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	FBXO38	0.05	0.01	blup	51	0.02	7.9e-03	-2.9	-7.7	1.6e-14	-0.66	0.05	0.17	FALSE
12	The Cancer Genome Atlas	Rectum Adenocarcinoma	FBXO38	0.13	0.17	enet	16	0.15	2.3e-04	7.8	-8.1	4.9e-16	-0.65	0.12	0.31	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	FBXO38	0.06	0.01	enet	7	0.01	3.2e-02	-3.8	-7.4	1.9e-13	-0.59	0.04	0.26	FALSE