[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr5:139,323,257-141,214,127

Best TWAS P=5.7e-10 · Best GWAS P=6.7e-08 conditioned to 0.445

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Heart Left Ventricle	PCDHB5	0.11	0.05	lasso	3	0.06	5.3e-04	4.8	6.2	5.7e-10	-0.80	0.06	0.80	TRUE
4	CommonMind	Brain Pre-frontal Cortex	ZMAT2	0.06	0.10	blup	360	0.09	1.4e-11	-4.8	-5.7	1.2e-08	0.85	0.19	0.80	FALSE
8	GTEx	Heart Left Ventricle	TMCO6	0.05	0.01	lasso	5	0.00	6.2e-01	-5.2	-5.6	2.5e-08	0.91	0.05	0.78	FALSE
6	GTEx	Cells Transformed fibroblasts	ZMAT2	0.04	0.02	lasso	4	0.02	2.4e-02	-5.4	-5.5	3.6e-08	0.96	0.05	0.88	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCDHA4	0.01	0.02	lasso	1	0.01	4.9e-04	-5.4	-5.4	6.8e-08	0.98	0.00	0.97	FALSE
11	METSIM	Adipose	DND1	0.08	0.11	lasso	5	0.10	7.3e-15	-5.4	5.3	9.7e-08	-0.98	0.06	0.94	FALSE
7	GTEx	Esophagus Mucosa	ZMAT2	0.06	0.02	enet	16	0.02	1.1e-02	4.5	-5.3	1.2e-07	0.78	0.08	0.83	FALSE
5	GTEx	Brain Hypothalamus	HARS	0.14	-0.01	enet	15	-0.01	6.3e-01	4.5	5.2	1.5e-07	-0.70	0.06	0.37	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZMAT2	0.03	0.03	enet	6	0.04	1.3e-04	-4.7	-5.2	1.5e-07	0.90	0.02	0.89	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	PCDHA13	0.02	0.01	enet	11	0.02	5.6e-03	4.8	5.2	1.6e-07	-0.64	0.01	0.83	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZMAT2	0.03	0.03	enet	5	0.03	7.7e-07	5.0	-5.2	1.9e-07	0.84	0.02	0.98	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PCDHA7	0.13	0.14	lasso	8	0.14	5.1e-17	-5.3	-5.2	2.0e-07	0.97	0.04	0.96	FALSE
10	GTEx	Nerve Tibial	HARS	0.07	0.01	enet	16	0.04	1.1e-03	-5.4	5.2	2.0e-07	-0.84	0.07	0.88	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	HARS2	0.03	0.03	lasso	5	0.02	2.9e-03	5.0	-5.2	2.0e-07	0.77	0.02	0.85	FALSE
1	CommonMind	Brain Pre-frontal Cortex	NDUFA2	0.02	0.01	bslmm	343	0.01	7.8e-03	-5.3	5.2	2.3e-07	-0.89	0.08	0.71	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PCDHA2	0.04	0.03	blup	478	0.03	5.0e-05	-4.8	-5.2	2.6e-07	0.83	0.11	0.89	FALSE