Best TWAS P=1.67e-10 · Best GWAS P=5.1e-10 conditioned to 0.239
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-967K21.1 | 0.08 | 0.02 | lasso | 8 | 0.01 | 2.1e-02 | -6.0 | -6.4 | 1.7e-10 | 0.89 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Adrenal Gland | RP11-967K21.1 | 0.22 | 0.02 | lasso | 4 | 0.02 | 6.5e-02 | -5.7 | -5.3 | 1.5e-07 | 0.84 | 0.04 | 0.65 | FALSE |
| 3 | GTEx | Artery Coronary | RP11-967K21.1 | 0.18 | 0.12 | lasso | 7 | 0.07 | 1.8e-03 | -5.8 | -6.0 | 1.5e-09 | 0.97 | 0.03 | 0.94 | FALSE |
| 4 | GTEx | Artery Tibial | RP11-967K21.1 | 0.09 | 0.10 | lasso | 11 | 0.07 | 2.4e-06 | -6.2 | -6.2 | 5.2e-10 | 0.97 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Colon Transverse | RP11-967K21.1 | 0.12 | 0.07 | lasso | 8 | 0.05 | 1.6e-03 | -6.2 | -5.8 | 7.6e-09 | 0.93 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Esophagus Muscularis | RP11-967K21.1 | 0.07 | 0.06 | lasso | 5 | 0.04 | 2.2e-03 | -6.2 | -5.8 | 5.6e-09 | 0.96 | 0.01 | 0.96 | FALSE |
| 7 | GTEx | Thyroid | RP11-967K21.1 | 0.05 | 0.00 | enet | 7 | 0.00 | 2.8e-01 | -3.9 | -5.2 | 1.7e-07 | 0.66 | 0.04 | 0.69 | FALSE |