Best TWAS P=1.46e-10 · Best GWAS P=9.3e-09 conditioned to 0.193
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RELT | 0.06 | 0.02 | blup | 318 | 0.04 | 4.1e-06 | 4.2 | 5.1 | 2.7e-07 | 0.59 | 0.23 | 0.64 | FALSE |
| 2 | GTEx | Whole Blood | RP11-809N8.4 | 0.08 | 0.06 | lasso | 2 | 0.04 | 6.5e-05 | 5.3 | 5.4 | 6.0e-08 | 0.91 | 0.04 | 0.96 | FALSE |
| 3 | NTR | Blood | RELT | 0.04 | 0.05 | lasso | 5 | 0.04 | 1.8e-13 | 5.6 | 5.7 | 1.6e-08 | 0.86 | 0.02 | 0.98 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | FAM168A | 0.03 | 0.02 | bslmm | 358 | 0.02 | 2.6e-03 | 4.3 | -6.4 | 1.5e-10 | -0.77 | 0.07 | 0.88 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RELT | 0.06 | 0.07 | blup | 35 | 0.08 | 3.5e-09 | 5.4 | 5.1 | 2.9e-07 | 0.89 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | ARHGEF17 | 0.04 | 0.03 | blup | 54 | 0.02 | 1.2e-02 | 4.6 | 5.5 | 5.1e-08 | 0.83 | 0.04 | 0.42 | FALSE |