TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr11:72,399,607-74,006,925
Best TWAS P=1.46e-10 · Best GWAS P=9.3e-09 conditioned to 0.193
72.4M
72.6M
72.8M
73M
73.2M
73.4M
73.6M
73.8M
74M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
ROSMAP
Brain Pre-frontal Cortex
FAM168A
0.03
0.02
bslmm
358
0.02
2.6e-03
4.3
-6.4
1.5e-10
-0.77
0.07
0.88
TRUE
3
NTR
Blood
RELT
0.04
0.05
lasso
5
0.04
1.8e-13
5.6
5.7
1.6e-08
0.86
0.02
0.98
FALSE
6
The Cancer Genome Atlas
Stomach Adenocarcinoma
ARHGEF17
0.04
0.03
blup
54
0.02
1.2e-02
4.6
5.5
5.1e-08
0.83
0.04
0.42
FALSE
2
GTEx
Whole Blood
RP11-809N8.4
0.08
0.06
lasso
2
0.04
6.5e-05
5.3
5.4
6.0e-08
0.91
0.04
0.96
FALSE
1
CommonMind
Brain Pre-frontal Cortex
RELT
0.06
0.02
blup
318
0.04
4.1e-06
4.2
5.1
2.7e-07
0.59
0.23
0.64
FALSE
5
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
RELT
0.06
0.07
blup
35
0.08
3.5e-09
5.4
5.1
2.9e-07
0.89
0.02
0.98
FALSE