Best TWAS P=4.68e-08 · Best GWAS P=5.38e-09 conditioned to 0.0404
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | PSMA4 | 0.18 | 0.14 | lasso | 1 | 0.11 | 6.5e-04 | -5.5 | -5.5 | 4.7e-08 | 0.94 | 0.01 | 0.94 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | CHRNA3 | 0.24 | 0.15 | enet | 5 | 0.16 | 6.5e-06 | -5.5 | 5.2 | 1.6e-07 | -0.90 | 0.00 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | CHRNA5 | 0.17 | 0.15 | lasso | 4 | 0.14 | 3.1e-05 | -5.5 | 5.1 | 2.7e-07 | -0.93 | 0.00 | 0.98 | FALSE |