TWAS
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Traits
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Traits
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Forced vital capacity (FVC), Best measure
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chr15:78,135,979-79,537,269
Best TWAS P=4.68e-08 · Best GWAS P=5.38e-09 conditioned to 0.0404
78.2M
78.4M
78.6M
78.8M
79M
79.2M
79.4M
79.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Liver
PSMA4
0.18
0.14
lasso
1
0.11
6.5e-04
-5.5
-5.5
4.7e-08
0.94
0.01
0.94
TRUE
2
The Cancer Genome Atlas
Esophageal Carcinoma
CHRNA3
0.24
0.15
enet
5
0.16
6.5e-06
-5.5
5.2
1.6e-07
-0.90
0.00
0.99
FALSE
3
The Cancer Genome Atlas
Esophageal Carcinoma
CHRNA5
0.17
0.15
lasso
4
0.14
3.1e-05
-5.5
5.1
2.7e-07
-0.93
0.00
0.98
FALSE