[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr16:80,779,331-82,901,701

Best TWAS P=1.97e-08 · Best GWAS P=5.64e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MPHOSPH6 0.30 0.24 lasso 8 0.23 2.1e-27 5.3 -5.1 2.7e-07 -0.97 0.01 0.99 TRUE
2 GTEx Adipose Visceral Omentum MPHOSPH6 0.32 0.14 lasso 4 0.17 3.5e-09 5.4 5.4 6.8e-08 0.98 0.01 0.99 FALSE
3 GTEx Artery Tibial MPHOSPH6 0.36 0.24 enet 9 0.27 1.9e-21 5.1 5.6 2.5e-08 0.96 0.03 0.97 FALSE
4 GTEx Cells Transformed fibroblasts CMIP 0.20 0.05 lasso 6 0.07 1.0e-05 -4.3 -5.6 2.0e-08 -0.25 0.55 0.42 TRUE
5 GTEx Colon Transverse MPHOSPH6 0.21 0.16 lasso 3 0.17 1.4e-08 5.1 5.2 2.0e-07 0.95 0.02 0.98 FALSE
6 GTEx Esophagus Muscularis MPHOSPH6 0.36 0.23 lasso 7 0.20 1.7e-12 5.1 5.1 2.9e-07 0.93 0.03 0.97 FALSE
7 GTEx Heart Left Ventricle MPHOSPH6 0.28 0.24 lasso 3 0.24 8.9e-13 5.1 5.2 2.0e-07 0.93 0.02 0.98 FALSE
8 GTEx Lung MPHOSPH6 0.16 0.10 lasso 4 0.11 8.3e-09 5.2 5.2 2.1e-07 0.95 0.01 0.98 FALSE
9 GTEx Pancreas MPHOSPH6 0.25 0.14 enet 15 0.15 9.2e-07 5.1 5.6 2.0e-08 0.89 0.01 0.99 TRUE
10 GTEx Stomach MPHOSPH6 0.41 0.10 lasso 7 0.09 3.5e-05 4.9 5.1 2.9e-07 0.93 0.03 0.97 TRUE
11 GTEx Testis MPHOSPH6 0.52 0.32 lasso 11 0.35 2.0e-16 5.1 5.4 5.7e-08 0.93 0.02 0.98 TRUE
12 GTEx Thyroid MPHOSPH6 0.31 0.21 lasso 4 0.26 4.7e-20 5.4 5.5 4.7e-08 0.98 0.01 0.99 FALSE
13 METSIM Adipose MPHOSPH6 0.12 0.07 bslmm 741 0.08 2.0e-11 4.9 5.4 5.3e-08 0.86 0.02 0.97 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH6 0.18 0.16 lasso 3 0.16 5.1e-15 5.2 5.3 1.0e-07 0.94 0.02 0.98 FALSE