Best TWAS P=1.11e-07 · Best GWAS P=1.25e-06 conditioned to 0.00462
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Uterus | SNAI3-AS1 | 0.47 | 0.00 | enet | 13 | 0.04 | 5.3e-02 | -2.4 | 5.1 | 2.7e-07 | -0.59 | 0.01 | 0.12 | FALSE |
2 | GTEx | Whole Blood | SNAI3-AS1 | 0.15 | 0.04 | enet | 21 | 0.10 | 6.7e-10 | 2.1 | 5.3 | 1.5e-07 | -0.56 | 0.05 | 0.72 | TRUE |
3 | METSIM | Adipose | CHMP1A | 0.27 | 0.05 | lasso | 9 | 0.07 | 1.3e-10 | 3.4 | 5.3 | 1.1e-07 | 0.08 | 0.11 | 0.22 | TRUE |
4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | DPEP1 | 0.06 | 0.01 | blup | 45 | 0.03 | 1.7e-03 | 3.4 | -5.3 | 1.5e-07 | -0.02 | 0.00 | 0.03 | FALSE |