Best TWAS P=1.92e-09 · Best GWAS P=1.07e-08 conditioned to 0.000209
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TSEN15 | 0.23 | 0.18 | lasso | 9 | 0.18 | 4.7e-21 | 5.7 | 5.6 | 1.7e-08 | 1.00 | 0.00 | 1.0 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | SMG7 | 0.10 | 0.00 | enet | 12 | 0.00 | 1.2e-01 | 5.4 | 5.4 | 8.2e-08 | -0.04 | 0.04 | 0.8 | TRUE |
| 3 | METSIM | Adipose | TSEN15 | 0.06 | 0.02 | enet | 28 | 0.04 | 1.3e-06 | 5.7 | 6.0 | 1.9e-09 | 0.81 | 0.00 | 1.0 | TRUE |