[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr1:217,760,821-220,479,607

Best TWAS P=4.69e-12 · Best GWAS P=1.71e-16 conditioned to 8.62e-11

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RRP15	0.55	0.46	enet	22	0.52	9.0e-74	5.2	5.9	3.1e-09	-0.04	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RRP15	0.24	0.14	lasso	2	0.12	3.2e-10	5.3	5.3	1.2e-07	-0.06	1.00	0.00	FALSE
3	GTEx	Adrenal Gland	RRP15	0.41	0.16	enet	30	0.12	5.6e-05	5.3	5.3	1.3e-07	-0.04	0.85	0.01	FALSE
4	GTEx	Artery Aorta	RRP15	0.23	0.17	lasso	3	0.15	8.3e-09	5.3	5.2	2.0e-07	-0.08	1.00	0.00	FALSE
5	GTEx	Artery Tibial	RRP15	0.19	0.16	lasso	4	0.14	8.7e-11	5.2	5.3	1.4e-07	-0.06	1.00	0.00	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	RRP15	0.34	0.25	lasso	4	0.22	1.9e-06	5.2	5.8	5.3e-09	-0.04	0.47	0.04	FALSE
7	GTEx	Cells Transformed fibroblasts	RRP15	0.38	0.28	lasso	6	0.28	1.9e-21	5.2	5.3	1.3e-07	-0.07	1.00	0.00	FALSE
8	GTEx	Esophagus Mucosa	RRP15	0.38	0.29	lasso	6	0.31	3.3e-21	5.3	6.0	2.3e-09	-0.06	1.00	0.00	FALSE
9	GTEx	Lung	RRP15	0.11	0.13	enet	21	0.13	2.6e-10	5.2	5.6	1.9e-08	-0.03	1.00	0.00	FALSE
10	GTEx	Muscle Skeletal	RRP15	0.17	0.15	lasso	2	0.14	3.9e-14	5.2	5.4	6.6e-08	-0.05	1.00	0.00	FALSE
11	GTEx	Pituitary	RRP15	0.38	0.23	lasso	3	0.23	1.9e-06	5.3	6.1	9.6e-10	-0.03	0.34	0.06	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RRP15	0.17	0.13	lasso	6	0.12	4.5e-10	5.3	5.3	1.1e-07	-0.07	1.00	0.00	FALSE
13	GTEx	Testis	RRP15	0.70	0.65	lasso	4	0.64	6.6e-36	5.2	5.4	8.0e-08	-0.06	1.00	0.00	FALSE
14	GTEx	Testis	ZC3H11B	0.33	0.28	lasso	3	0.27	1.5e-12	-5.5	-5.5	3.3e-08	0.04	0.00	1.00	TRUE
15	GTEx	Thyroid	RRP15	0.28	0.16	lasso	7	0.17	9.8e-13	5.3	5.9	3.4e-09	-0.03	1.00	0.00	FALSE
16	METSIM	Adipose	RRP15	0.28	0.24	bslmm	489	0.23	1.7e-34	5.3	5.7	1.1e-08	0.00	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	RRP15	0.11	0.11	lasso	5	0.10	2.5e-20	5.2	5.2	2.3e-07	-0.05	0.98	0.02	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RRP15	0.13	0.13	lasso	1	0.10	1.4e-05	5.3	5.3	1.3e-07	-0.06	0.74	0.04	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RRP15	0.07	0.07	lasso	2	0.06	2.0e-07	6.9	6.9	4.7e-12	-0.03	0.00	1.00	TRUE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RRP15	0.17	0.11	enet	9	0.12	7.4e-13	5.2	5.2	1.9e-07	-0.03	0.98	0.02	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RRP15	0.14	0.04	enet	11	0.06	4.0e-04	5.2	5.2	1.7e-07	-0.03	0.12	0.38	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	RRP15	0.10	0.10	lasso	1	0.10	4.7e-11	5.2	5.2	1.7e-07	-0.05	0.98	0.02	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	RRP15	0.09	0.09	lasso	3	0.09	3.2e-10	5.2	5.1	2.8e-07	-0.06	0.98	0.02	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RRP15	0.10	0.09	lasso	3	0.08	9.8e-10	5.3	5.3	9.6e-08	-0.06	0.98	0.02	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RRP15	0.15	0.12	lasso	2	0.12	1.9e-05	5.3	5.3	1.3e-07	-0.06	0.16	0.14	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	RRP15	0.29	0.29	lasso	2	0.29	2.7e-30	5.2	5.3	1.4e-07	-0.06	0.98	0.02	FALSE
27	The Cancer Genome Atlas	Soft Tissue Sarcoma	TGFB2	0.05	0.03	blup	73	0.03	4.5e-03	6.9	-6.5	7.6e-11	-0.90	0.01	0.88	TRUE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	RRP15	0.11	0.09	lasso	3	0.07	8.2e-06	5.3	5.2	1.6e-07	-0.06	0.24	0.71	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	RRP15	0.22	0.25	lasso	3	0.24	1.7e-23	5.2	5.2	1.5e-07	-0.06	0.98	0.02	FALSE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TGFB2	0.24	0.11	enet	10	0.14	1.4e-04	5.9	-5.9	4.6e-09	-0.80	0.08	0.63	FALSE