TWAS
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Models
Genes
Traits
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Traits
:
Forced vital capacity (FVC), Best measure
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chr1:227,222,963-228,614,123
Best TWAS P=2.13e-10 · Best GWAS P=7.51e-09 conditioned to 0.00275
227.2M
227.4M
227.6M
227.8M
228M
228.2M
228.4M
228.6M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells EBV-transformed lymphocytes
JMJD4
0.13
0.06
lasso
4
0.03
0.029
-5.3
-6.3
2.1e-10
0.5
0.04
0.61
TRUE